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Blood, Heart and Circulation

Clinical trial in trauma patients to evaluate drug that stops excessive bleeding​

By Kristina Sauerwein - Researchers at Washington University School of Medicine in St. Louis will evaluate a drug that stops excessive bleeding ...

Ultrasound can measure effects of atherosclerosis drugs

Newly introduced advanced ultrasound technology can be used to carefully study carotid arteries, the main blood vessels that supply the brain, and ...

Blood test results vary from drop to drop in finger prick tests

Rice study: Six to nine drops of blood may be needed for consistent measurements ... Full story

Study: Blood vessels store, secrete key blood-clotting protein

Rice University researchers solve long-standing mystery about hemophilia protein ... Full story

New insights in sprouting angiogenesis

Sprouting angiogenesis drives blood vessel growth in healthy and diseased tissues. Holger Gerhardt (VIB Vesalius Research Center, KU Leuven) together with international colleagues now show that, in contrast to current concepts, the stalk-cell phenotype needs to be actively repressed to allow tip-cell formation. ... Full story

A step forward in obtaining blood stem cells in laboratory

This study is of great relevance to regenerative medicine as, in the future, it will make it possible to produce cells that can be used for haematological transplants in patients with no compatible donors ... Full story

Can a “Sense” DNA Drug Reverse the Actions of an Antisense Drug to Treat Blood Clots and Prevent Bleeding?

New Rochelle, NY —Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study. The sense oligonucleotide antidote reversed the actions of the antisense antithrombotic drug in the mouse model and prevented the bleeding that commonly occurs with anti-coagulation therapy, as described in an article in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. The article is available free on the Nucleic Acid Therapeutics website until November 12, 2015. ... Full story

Young women less likely to be prescribed or take post-heart attack meds

American Heart Association Rapid Access Journal Report ... Full story

New Approach to Treating Heparin-induced Blood Disorder Revealed in Structure of Protein-Antibody Complex, Penn Study Finds

PHILADELPHIA – A potential treatment for a serious clotting condition that can strike patients who receive heparin to treat or prevent blood clots may lie within reach by elucidating the structure of the protein complex at its root, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The team’s work, published in Nature Communications, established that an antibody that disrupts the complex may have therapeutic potential. Almost 12 million patients are given heparin annually either as treatment for clots or to prevent clot formation, for example, during cardiopulmonary bypass surgery. ... Full story

New technology enables people to take own blood samples at home

New technology enables people to take own blood samples at home ... Full story

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