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Blood, Heart and Circulation

Bioengineered blood vessel is safe for dialysis patients, study finds

By Ziba Kashef - Bioengineered blood vessels may prove to be safer and last longer than synthetic vessels for patients on dialysis. ...

New Rule Gives FDA Tighter Grip on Tobacco, Says American Heart Association

Washington, D.C – American Heart Association CEO Nancy Brown issued the following comments today on the Food and Drug Administration’s (FDA) ...

Weight loss surgery boosts good cholesterol in obese teen boys

American Heart Association Meeting Report Abstract 195 ... Full story

Why Are Women less likely to be Prescribed Statins than Men?

Statins are equally effective at decreasing risk of coronary events in men and women, and yet women are less likely to be prescribed these cholesterol-lowering drugs than men. ... Full story

National Hospital System Uses Enterprise Approach for Assessing Bleeding Risks

Orlando, Fla. – The largest risk-directed study by a national hospital system demonstrates a 40 percent decline in bleeding events for percutaneous coronary intervention (PCI) patients and a significant reduction in pharmacy costs. This quality improvement project (QIP) study was presented today as a late-breaking clinical trial at the Society for Cardiovascular Angiography and Interventions (SCAI) 2016 Scientific Sessions in Orlando, Fla. ... Full story

Human heart cells show stress response to tobacco smoke, but not to e-cig vapour

New research has showed substantial differences in the way human heart cells respond to e-cigarette smoke and conventional cigarette smoke. ... Full story

Oscillations determine whether blood vessels grow thicker or branch

Microscopic images of a mouse retina. On the left the new blood vessels are in branching mode; on the right they are increasing in diameter under the influence of the VEGFA hormone. The cell membrane is colored green, the cell nuclei blue, and the oscillating signal molecules red. ... Full story

New insights in how blood vessels increase their size

A new study from the group of Holger Gerhardt (VIB/KU Leuven/Cancer Research UK/ MDC/BIH Berlin) in collaboration with Katie Bentley’s Lab (Cancer Research UK/BIDMC-Harvard Medical School) addresses a long standing question in the wider field of developmental biology and tissue patterning in general, and in the vascular biology field in particular: ‘What are the fundamental mechanisms controlling size and shape of tubular organ systems’. Whereas the most obvious way to grow a tube in size would be to add more building blocks (by proliferating cells) to enlarge its circumference, or to increase the size of the building blocks (the cells, hypertrophy), an alternative way would be to rearrange existing building blocks. Benedetta Ubezio, Raquel Blanco and colleagues under the direction of Holger Gerhardt and Katie Bentley now show that cell rearrangement is the way blood vessels switch from making new branches to increasing the size of a branch. The researchers also found that this switch is triggered by synchronization of cells under the influence of increasing levels of the growth factor VEGFA. ... Full story

Shorter Times to Blood Transfusion Reduce Death Risk in Trauma Patients

CINCINNATI—Patients who get blood quickly after severe injuries are less likely to die, according to researchers from the University of Cincinnati (UC) Department of Emergency Medicine. ... Full story

Use of clot-blocking device should be rare, UC Davis study finds

Vena cava filters benefit a small portion of patients with leg or lung blood clots, but can also increase blood-clot risks ... Full story

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