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Bones and Muscles

Stem cells faulty in Duchenne muscular dystrophy, researchers find

In a mouse model of Duchenne muscular dystrophy, muscle stem cells express connective-tissue genes associated with fibrosis and muscle weakness, according to ...

Healthy bones for life

Healthy bones are key for healthy ageing. The foundations of a healthy skeleton are laid down early in life, but our dietary ...

Long-term endurance training impacts muscle epigenetics

A new study from Karolinska Institutet in Sweden shows that long-term endurance training in a stable way alters the epigenetic pattern in the human skeletal muscle. The research team behind the study, which is being published in the journal Epigenetics , also found strong links between these altered epigenetic patterns and the activity in genes controlling improved metabolism and inflammation. The results may have future implications for prevention and treatment of heart disease, diabetes and obesity. ... Full story

Human trials show drug success for treatment of genetic bone disease

AKU was the first human disorder that was recognised as a genetic disease 100 years ago, but is often mistaken for severe arthritis ... Full story

Is a brace necessary for spinal fracture healing?

Patients with spinal compression fractures who wore no brace fared as well as patients instructed to wear a brace for treatment ... Full story

Structure and mechanism of ryanodine receptor revealed - step forward in understanding muscle diseases

Every single moment our life depends on the reliable functioning of muscles. Even slight malfunction of muscles results in diseases. To be able to treat and prevent muscle associated disease we need to understand their structure and function in molecular details. ... Full story

Prompt, appropriate medical care for dislocated shoulder injuries prevents repeat dislocations

ROSEMONT, Ill.—Prompt and appropriate treatment of a dislocated shoulder—when the head of the upper arm bone (humerus) is completely knocked out of the shoulder socket (glenoid)—can minimize risk for future dislocations as well as the effects of related bone, muscle and nerve injuries, according to a literature review appearing in the December issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS). ... Full story

Men have twice the death rate from hip fractures

Researchers at the University of Adelaide say they're concerned about the findings of new research confirming that older men have a much higher risk of dying in the first 12 months after a hip fracture. ... Full story

Study by UCLA scientists reveals new findings about cause of lesions around jaw bone

IMPACT - Osteonecrosis of the jaw is a debilitating and painful condition in which oral lesions develop in individuals taking drugs such as bisphosphonate or denosumab, which are commonly used in treatments for osteoporosis and for cancers that have spread to the bones. ... Full story

Study highlights under 5s at risk from broken bones

Public health researchers have discovered new clues about which children under five years old are the most at risk from broken bones in childhood accidents. ... Full story

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