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Alzheimer’s

New target identified in fight against Alzheimer’s, multiple sclerosis

By Michael C. Purdy - Normally, brain cells known as microglia (green) surround Alzheimer’s plaques (blue) to help clear such ...

Alzheimer's disease linked to heart's effect on the brain

The prevailing medical wisdom that Alzheimer's Disease has its origins in the brain has a radical and disputed rival with shocking implications ...

Experts criticise ‘inaccurate’ view that B Vitamins have no role in Alzheimer’s disease prevention

Patients in the very early stages of dementia could miss out on a potentially effective treatment after misleading research was published last year, say medical experts. ... Full story

Skin Test May Shed New Light on Alzheimer’s and Parkinson’s Diseases

WASHINGTON, DC – Scientists have discovered a skin test that may shed new light on Alzheimer’s and Parkinson’s diseases, according to a study released today will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, D.C., April 18 to 25, 2015. The study showed that skin biopsies can be used to detect elevated levels of abnormal proteins found in the two diseases. ... Full story

Project maps human epigenome, discovers immune system role in Alzheimer’s

The epigenome controls gene expression across diverse cell types, and integrates genetic and environmental signals. A new reference map will help interpret the genetic basis for disease. ... Full story

Epigenomics of Alzheimer’s disease progression

Study of epigenomic modifications reveals immune basis of Alzheimer's disease. ... Full story

Tau-Associated MAPT Gene Increases Risk for Alzheimer’s Disease

Finding could improve dementia diagnosis and treatment ... Full story

Promising results for new Alzheimer therapy

Scientists at Karolinska Institutet have evaluated a new Alzheimer’s therapy in which the patients receive an implant that stimulates the growth of a certain type of nerve cell. The results, which are published in the journal Alzheimer's & Dementia , suggest that the introduction of a nerve growth factor can prevent neuronal degradation in Alzheimer’s patients. ... Full story

USC neurogeneticists harness immune cells to clear Alzheimer’s-associated plaques from rodent brains

Image: A 3D reconstruction of an immune cell (red) containing β-amyloid (blue) within an intracellular degradation compartment (yellow). Deletion of the anti-inflammatory cytokine, Il10, activates innate immune cells to clear the brain of toxic β-amyloid plaques. Image by Marie-Victoire Guillot-Sestier, Ph.D. ... Full story

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