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Breast Cancer

'Junk' DNA plays role in preventing breast cancer

Supposed 'junk' DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and ...

Huge gains made in breast cancer treatment at the MUHC

An ongoing clinical trial using new intraoperative technology is producing significant results for breast cancer patients ...

Where women live influences decisions about breast cancer treatment

New joint research has found that the distance to cancer services may be influencing the treatment intentions of regional Queensland women diagnosed with breast cancer. ... Full story

Penn Study Suggests New Recommendations to Reduce Radiation Risk from Digital Screening Mammography

Higher Risk of Radiation-Induced Breast Cancer Found in Women Screened More Frequently and in Women with Larger Breasts ... Full story

Sugar in Western diets increases risk for breast cancer tumors and metastasis

MD Anderson study in mice points to sugar’s impact on inflammatory pathways as culprit ... Full story

Study Identifies Characteristics that May Increase a Breast Cancer Survivor’s Risk of Developing Leukemia Following Treatment

A new analysis indicates that certain characteristics may increase a breast cancer survivor’s risk of developing leukemia after undergoing chemotherapy and/or radiation. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings are a first step toward finding ways to prevent this serious and potentially life-threatening treatment-related complication. ... Full story

New Breast Cancer Drug May be Effective against Other Types of Cancer, Abramson Cancer Center Experts Find

Palbociclib, in Combination with Other Therapies, Has Potentially Powerful Effect ... Full story

T Cells That Recognize HER2 Receptor May Be Key to Preventing HER2+ Breast Cancer Recurrence, Penn Study Finds

PHILADELPHIA – Recurrence of HER2-positive breast cancer after treatment may be due to a specific and possibly cancer-induced weakness in the patient’s immune system – a weakness that in principle could be corrected with a HER2-targeted vaccine – according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Results of the study show that T cells from patients whose breast cancer had recently recurred showed far weaker response to the HER2 receptor protein, compared to T cells from patients whose breast cancer had not recurred over a long period following treatment. The study, published in JAMA Oncology this week, suggests that patients with HER2-positive breast cancer – which accounts for roughly 20 percent of the 260,000 invasive breast cancers diagnosed in the US each year – might someday undergo immune status monitoring with blood tests before, during and after treatment, to allow physicians to gauge the risk of recurrence, and possibly to reduce that risk with therapies that boost anti-HER2 immunity. ... Full story

Method for better treatment of breast cancer

A new study shows that a novel imaging-based method for defining appropriateness of breast cancer treatment is as accurate as the current standard-of-care and could reduce the need for invasive tissue sampling. The results suggest that the method might lead to more optimal treatment of individual patients. ... Full story

Milk-producing protein ‘goes rogue’ to drive breast cancer spread

A protein that controls milk production in the breast after pregnancy can ‘go rogue’ in breast cancer and drive the spread of cancer cells to the lungs, Australian researchers have shown. Their work shows that the rogue protein, called Elf5, summons immune cells to gather in breast tumours. In a model of breast cancer, this caused inflammation and encouraged new blood vessels to form around the tumour. These blood vessels became ‘leaky’, opening a gateway for cancer cells to escape into the blood and, ultimately, to spread to lung. ... Full story

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