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Cost-effectiveness of Herceptin for early stage breast cancer varies by age and tumour type

A new study from the University of Otago, Wellington (UOW) found that the cost-effectiveness of the drug trastuzumab (known more commonly as ...

A key to unlocking the mystery of triple negative breast cancer

RI-MUHC research could lead to new breast cancer treatments linked to prolactin receptor ...

New tool detects malignant breast cancer tissue during surgery

A tool that will enable surgeons to detect malignant breast cancer tissue during surgery using new imaging techniques has been developed by researchers at The University of Western Australia and the Harry Perkins Institute of Medical Research. ... Full story

Innovative drug could revolutionise the treatment of early-stage breast cancer

Vienna - The large-scale international study ABCSG 42/PALLAS is currently investigating whether a drug that is already showing great promise in the treatment of metastasised breast cancer might also increase the success of treatment of the most common type of breast cancer: early-stage hormone-receptor-positive, HER2-negative breast cancer. The study is being conducted in the USA and in other countries including Austria, Australia, Belgium and Spain, for example. The lead investigator for all countries outside the USA is Michael Gnant, Head of the Breast Health Center at MedUni Vienna and Vienna General Hospital, Deputy Head of the Comprehensive Cancer Center (CCC) Vienna and President of the Austrian Breast & Colorectal Cancer Study Group (ABCSG). Over the course of the next two years, up to 500 patients from Austria can be included in the study. ... Full story

Multidisciplinary team develops automated method for detecting breast cancer

An international team comprising engineers, mathematicians and doctors has applied a technique used for detecting damage in underwater marine structures to identify cancerous cells in breast cancer histopathology images. ... Full story

Clinical Trials Test Dietary Therapy for Triple-Negative Breast Cancer

Madison, Wisconsin - A new clinical trial for women with clinically aggressive triple-negative breast cancer (TNBC) will test a novel theory: Will a diet low in an essential nutrient make TNBC cells more vulnerable to cell killing by a new cancer drug? ... Full story

New mammogram hotspots predict future breast cancers

Melbourne researchers have discovered a new way to interpret mammograms that could transform routine breast screening and save lives. Professor John Hopper said the new technique ... Full story

Viral particles support prophylactic vaccination against breast cancer

Artificial structures of tumour antigens, so-called mimotopes, applied in vaccinations of cancer patients can trigger a long-term immune response. For the vaccine, however, a carrier is required that triggers an immune response itself. A team of researchers from the Messerli Research Institute of Vetmeduni Vienna and the Meduni Vienna showed in laboratory tests that virus-like particles of harmless adeno-associated viruses (AAV) are particularly suitable as carriers. The scientists were able to produce mimotopes for the growth factor HER2, a tumour antigen of about 30 percent of breast tumours, without chemical after-treatment at these AAV carrier particles and use them directly as a specific vaccine. In the future, this vaccine could serve as a prophylaxis for high-risk patients or breast cancer patients that have already received a therapy. Due to close similarities of the growth factor in humans and dogs, also a treatment of canine breast tumours seems possible. The results were published in the journals OncoImmunology and Oncology Letters. ... Full story

Roots of resistance to cancer drugs runs deeper than a single gene

By Bill Hathaway   October 10, 2016 (© Searching for more individual genes to predict responses to breast cancer therapy may not work, a new study suggests. Instead, ... Full story

Fulvestrant breast cancer drug shows better survival than current standard, study finds

The advanced breast cancer hormone therapy ‘fulvestrant’ works better than the current standard drug treatment and reduces the risk of progression by 20%, according to a large clinical trial led by The University of Nottingham and Baylor College of Medicine in the US. ... Full story

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