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Mutation in Well-studied p53 Tumor Suppressor Protein Uses Epigenetic Pathways to Drive Aggressive Cancer Growth

PHILADELPHIA – Aggressive cancer growth and alterations in gene activity without changes in DNA sequence (epigenetics) are associated with mutant p53 proteins, ...

Research on Women's Cancers Lacking in Poor and Middle-Income Countries

Low- and middle-income countries (LMICs) see millions of cases of breast and cervical cancer each year, but much of the research on these diseases is based in wealthier countries that have far greater resources and treatment options available, according to a review of existing research published Sept. 1 by the CDC’s Global and Territorial Health Research Network. ... Full story

Brazilian wasp venom kills cancer cells by opening them up

The venom of a wasp native to Brazil could be used in the fight against cancer, according to new University of Leeds research. ... Full story

New devils research finds facial tumours are evolving to benefit themselves

New devils research finds facial tumours are evolving to benefit themselves ... Full story

NCCN Publishes a Resource-Stratified Framework of Clinical Practice Guidelines for Cervical Cancer

NCCN has published the NCCN Framework for Resource Stratification of NCCN Guidelines (NCCN Framework™) for Cervical Cancer; the NCCN Framework™ guides evidence-based adaptation to available clinical treatment resources. ... Full story

Patient Overcomes Colorectal Cancer, Urges Importance of Screening

Paula Hoevel, 60, a Madisonville resident, says that five years ago, stomach pains led her to an appointment with her general practitioner. ... Full story

"Eat me" signal whets appetites for tumor-devouring dendritic cells, in the right cancer-control model

By changing the mouse model they use to study how the immune system responds to cancer, a team of researchers hopes to shift the focus for one form of cancer immunotherapy back to the standard approach -- relying on antigen-presenting dendritic cells -- and away from the current upstart, macrophages. ... Full story

Promising class of new cancer drugs causes memory loss in mice

Cancer researchers are constantly in search of more-effective and less-toxic approaches to stopping the disease, and have recently launched clinical trials testing a new class of drugs called BET inhibitors. These therapies act on a group of proteins that help regulate the expression of many genes, some of which play a role in cancer. ... Full story

Researchers develop framework for value based pricing of cancer drugs

At a time when cancer drug prices are rising rapidly, an innovative new study provides the framework for establishing value based pricing for all new oncology drugs entering the marketplace. Using a highly sophisticated economic model, researchers from Winship Cancer Institute of Emory University and Georgia Institute of Technology used an example of a new lung cancer drug. ... Full story

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