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Two studies identify a detectable, pre-cancerous state in the blood

Findings pave way for new lines of cancer research focused on detection and prevention ...

Vaccines may make war on cancer personal

By Michael C. Purdy -In the near future, physicians may treat some cancer patients with personalized vaccines that spur their immune systems ...

Most comprehensive global study to date shows wide gulf in cancer survival between countries

The most comprehensive international comparison of cancer survival to date, covering countries that are home to two-thirds of the world’s population, shows extremely wide differences in survival between countries. ... Full story

Study finds potential predictive biomarker for response to PD-L1 checkpoint blocker

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine. ... Full story

Experiments on mice offer hope for effective leukaemia treatment

Scientists have discovered a weak point in leukaemia stem cells which it appears could be utilised in effective treatment of acute myeloid leukaemia. ... Full story

Survivors of childhood eye cancer experience normal cognitive functioning as adults

St. Jude Children’s Research Hospital study found adults diagnosed with retinoblastoma as infants often performed better on tasks than survivors diagnosed at an older age; suggests brain may compensate for early insult ... Full story

Using intelligence to understand cancer's defence against immunity

A team from the University of Birmingham are looking to receive a boost to their research into a treatment for cancers linked to Epstein-Barr Virus (EBV) through a pioneering crowdfunding scheme. ... Full story

Researchers identify new ways to drain cancer’s ‘fuel tank’

Scientists at the University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment, by targeting the ‘fuel’ part of stem cells which allows tumours to grow. ... Full story


A world-first human trial will test an experimental brain cancer treatment resulting from major discoveries by a team of scientists from the QIMR Berghofer Medical Research Institute, Ludwig Institute for Cancer Research (LICR) and Monash University. ... Full story

An unexpected bonus – blocking STAT3 could help cancer patients in two ways

The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumour cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumour immunity. Anti-STAT3 therapy may thus be highly promising. ... Full story

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