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Research in the News: Sabotage as therapy: aiming lupus antibodies at vulnerable cancer cells

By Vicky Agnew - Yale Cancer Center researchers may have discovered a new way of harnessing lupus antibodies to sabotage cancer cells ...

Caffeine helps cancer survivors reach exercise goals

Caffeine may improve exercise capacity and reduce fatigue in cancer survivors, a University of Queensland study has found. ...

New understanding of a mechanism by which cells try to arrest oncogene action

Cold Spring Harbor, NY -- What happens inside cells when they detect the activation of a cancer-inducing gene? Sometimes, cells are able to signal internally to stop the cell cycle. Such cells are able to enter, at least for a time, a protective non-growth state. ... Full story

Drug Shows Promise for Subset of Stage III Colon Cancer Patients

Bethesda, MD — A subset of patients with stage III colon cancer had improved survival rates when treated with irinotecan-based therapy, according to a new study in Gastroenterology,1 the official journal of the American Gastroenterological Association. ... Full story

Study shows potential method to better control lung cancer using radiotherapy

Manchester scientists are working out how to safely increase the radiotherapy dose given to lung cancer patients – potentially offering improved local control and survival. ... Full story

Promising new cancer therapy uses molecular ‘Trash Man’ to exploit a common cancer defense

While many scientists are trying to prevent the onset of a cancer defense mechanism known as autophagy, researchers at Virginia Commonwealth University Massey Cancer Center are leveraging it in a new therapy that causes the process to culminate in cell death rather than survival. The novel treatment strategy targets the p62 protein, which is often referred to as the “Trash Man” due to its role in disposing unwanted cellular proteins during autophagy. Results from preclinical experiments suggest this experimental treatment approach could be particularly effective against multiple myeloma and potentially other forms of blood cancers. ... Full story

Circulating tumor cell clusters more likely to cause metastasis than single cells

Circulating tumor cell (CTC) clusters – clumps of from 2 to 50 tumor cells that break off a primary tumor and are carried through the bloodstream – appear to be much more likely to cause metastasis than are single CTCs, according to a study from investigators at the Massachusetts General Hospital (MGH) Cancer Center. ... Full story

New approach could transform treatment of depression in cancer patients

Around three-quarters of cancer patients who have major depression do not currently receive treatment for their depression, new research led by Oxford University has found. But the researchers show that a new treatment programme is strikingly more effective at reducing depression and improving quality of life among cancer patients than current care. ... Full story

New hope in cancer double blow

CLINICAL TRIALS TO TEST NEW WAY TO PREVENT TRANSPLANT COMPLICATIONS ... Full story

Cancer Leaves a Common Fingerprint on DNA

Chemical alterations to genes appear key to tumor development ... Full story

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