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Lung Cancer

Immunotherapy drug shows success in treating advanced lung cancer

UCLA researchers say study also will help identify which people could respond best to treatment ...

“Liquid Biopsy” May Help Earlier Detection of Lung Cancer Treatment Resistance

PHILADELPHIA — A blood test to regularly monitor for the presence of rearrangement of the EML4-ALK gene fusion in patients with non-small ...

Pembrolizumab Promising for Lung Cancer, Clinical Outcomes Correlate With Biomarker

​ PHILADELPHIA — The immunotherapy pembrolizumab was found to be safe and yielded durable responses in patients with advanced, non-small cell lung cancer (NSCLC), and those with high levels of the protein PD-L1 in their tumors had better clinical outcomes, according to phase I KEYNOTE-001 clinical trial data presented here at the AACR Annual Meeting 2015, April 18-22. ... Full story

Ovarian cancer: Genetic testing should be accessible to all women with the disease

It is estimated that this year in Canada, 2,600 women will be newly diagnosed with this disease. ... Full story

Dual Therapy’s One-Two Punch Knocks Out Drug-Resistant Lung Cancer

Unusual Chance to Study Patient’s Residual Tumor Leads to New Finding ... Full story

Moffitt Cancer Center Clinical Trials Help Lead to FDA Approval of New Lung Cancer Immunotherapy

TAMPA, Fla. – Clinical trials held at Moffitt Cancer Center have helped lead to the Food and Drug Administration approval of Opidivo (nivolumab), the first and only immunotherapy for patients with advanced non-small cell lung cancer. ... Full story

Indicators related to lung cancer recurrence, metastases and survival can inform treatment of patients

A new study describes prognostic factors for lung cancer spread and recurrence, as well as subsequent risk of death from the disease. NCI investigators evaluated these indicators in nearly 2,100 people in the Lombardy region of Italy who were diagnosed with lung cancer between 2002 and 2005 and who had participated in the Environment and Genetics in Lung cancer Etiology (EAGLE) study. ... Full story

FDA expands approved use of Opdivo to treat lung cancer

The U.S. Food and Drug Administration today expanded the approved use of Opdivo (nivolumab) to treat patients with advanced (metastatic) squamous non-small cell lung cancer (NSCLC) with progression on or after platinum-based chemotherapy. ... Full story

Researchers Identify Genes Responsible for Lung Tumors

(Boston)–The lung transcription factor Nkx2-1 is an important gene regulating lung formation and normal respiratory functions after birth. Alterations in the expression of this transcription factor can lead to diseases such as lung interstitial disease, post-natal respiratory distress and lung cancer. ... Full story

Research in the News: Liquid biopsy: A real-time blood test for solid lung cancer tumors

By Vicky Agnew - In the rapidly changing world of molecular profiling for genetic diseases, cancer researchers are increasingly optimistic about the reality of a simple blood test to monitor and treat solid tumor cancers. ... Full story

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