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VICC trial putting lung cancer therapy to the test

Vanderbilt-Ingram Cancer Center (VICC) is leading a Phase 3 global trial of a cancer therapy that was initially tested and validated in ...

Pembrolizumab New Option for First Line Treatment of Patients with Advanced Lung Cancer and High PD-L1 Expression

LUGANO-COPENHAGEN – Pembrolizumab is set to become a new option for first line treatment of patients with advanced lung cancer and high ...

Neoadjuvant Immunotherapy Prior to Surgery is Safe and Feasible in Early Lung Cancer

LUGANO-COPENHAGEN – Neoadjuvant immunotherapy with the PD-1 inhibitor nivolumab is safe and feasible prior to surgery for early lung cancer, researchers reported at the ESMO 2016 Congress in Copenhagen. ... Full story

Study identifies new way to suppress lung tumors

By Ziba Kashef Changes in cell distribution for growth promoting proteins (EGFR;red) when addition of sugar chains is decreased by the inhibitor, NGI-1. Proteins without sites ... Full story

IL-34: a new, possible target to tackle drug-resistant cancer cells

A team of researchers has discovered that chemoresistant lung cancer cells suppress immune functions and strengthen resistance to chemotherapy by producing interleukin-34 (IL-34)—a type of cytokine. ... Full story

Scientists find lethal vulnerability in treatment-resistant lung cancer

DALLAS – Researchers working in four labs at UT Southwestern Medical Center have found a chink in a so-called “undruggable” lung cancer’s armor – and located an existing drug that might provide a treatment. ... Full story

Liquid Biopsy: Level of mutated DNA in the blood corresponds to patient outcome

New findings from a scientific collaboration between the German Cancer Research Center (DKFZ), the National Center for Tumor Diseases (NCT) Heidelberg and the Thoraxklinik Heidelberg suggest liquid biopsy as a promising tool to monitor lung cancer patient tumors early. Scientists associated liquid biopsy readouts with clinical data and were able to track tumor responses to cancer drugs in real-time. Their paper has just been published in the latest issue of Scientific Reports. ... Full story

Drug-loaded synthetic nanoparticles can distinguish lung cancer cells from healthy cells

DALLAS – Researchers with the Harold C. Simmons Comprehensive Cancer Center successfully developed a synthetic polymer that can transport a drug into lung cancer cells without going inside of normal lung cells. ... Full story

Case for Liquid Biopsies Builds in Advanced Lung Cancer

Penn Study Addresses Unmet Need for Better, Non-Invasive Tests Called Out in Recent "Moonshot" Blue Ribbon Panel Report ... Full story

Research questions whole brain radiotherapy for older lung cancer patients

Older lung cancer patients whose disease has spread to the brain could be spared potentially harmful radiotherapy, new research indicates. ... Full story

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