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Ovarian Cancer

RPCI Researchers Identify Priority Targets for Immunotherapy in Epithelial Ovarian Cancer

Findings suggest that several MAGE proteins may prove to be biomarkers for the disease ...

Children’s poor development linked to risk factors

Routinely collected health data on pregnant women could be used in a better way to identify ‘at risk’ children earlier and more ...

MD Anderson researchers discover new route for ovarian cancer spread

HER3-positive circulating tumor cells home in on omentum; new target to thwart metastasis ... Full story

Finding the Achilles’ Heel of Ovarian Tumor Growth

A team of scientists, led by principal investigator David D. Schlaepfer, PhD, professor in the Department of Reproductive Medicine at the University of California, San Diego School of Medicine report that small molecule inhibitors to a protein called focal adhesion kinase (FAK) selectively prevent the growth of ovarian cancer cells as tumor spheroids. ... Full story

Genetic pathway can slow spread of ovarian cancer

University of Adelaide research into the origins of ovarian cancer has led to the discovery of a genetic pathway that could slow the spread of the cancer. ... Full story

Clinical trial analysis suggests drug combination may be highly effective in recurrent ovarian cancer

Significant improvement with the use of a combination drug therapy for recurrent ovarian cancer was reported at the annual meeting of the American Society of Clinical Oncology (ASCO) meeting in Chicago today. ... Full story

Combination therapy shows promise against forms of breast and ovarian cancer in early clinical trial

A two-drug combination that disrupts critical signaling circuits in cancer cells has produced an observable benefit in patients with recurrent high-grade serous ovarian cancer (HGSC) or triple-negative breast cancer (TNBC). These results, from a phase I clinical trial of the regimen, will be reported by Dana-Farber Cancer Institute investigators at the annual meeting of the American Society of Clinical Oncology (ASCO) on Saturday, May 31, 2014. ... Full story

Life-extending ovarian cancer chemotherapy underused, study finds

Patients with non-metastatic ovarian cancer live an average of 16 months longer when chemotherapy is delivered into the abdomen instead of by standard intravenous infusion, yet only a minority of eligible patients are receiving it, report scientists from Dana-Farber Cancer Institute. ... Full story

Where children get their wellbeing

by Marketing and Communications - A national survey of 8 to 14-year-olds will ask them about their wellbeing. ... Full story

Ovarian Cancer Cells Are More Aggressive On Soft Tissues

When ovarian cancer spreads from the ovaries it almost always does so to a layer of fatty tissue that lines the gut. A new study has found that ovarian cancer cells are more aggressive on these soft tissues due to the mechanical properties of this environment. The finding is contrary to what is seen with other malignant cancer cells that seem to prefer stiffer tissues. ... Full story

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