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Digestive System

You're Not Alone: Solutions for Managing Pelvic Floor Disorders

Hollywood actress Kate Winslet made headlines when she admitted to having occasional urinary incontinence, confessing that “I can’t jump on trampolines anymore; ...

The world’s largest bacterial study of baby poo

Daily samples of baby poo taken throughout a full year will reveal how the bacterial community changes in the gut of infants. ...

Biotech one step closer to bowel disease treatment

University of Queensland spin-out biotech company Protagonist Therapeutics Inc is a step closer to developing a new drug that would benefit millions of people worldwide. The ... Full story

Better off without it: Broken gene may help protect against ulcerative colitis

By Veronica Meade-Kelly, Broad Communications We often think of the body as a machine, with every part—right down to each single gene—working with optimal efficiency to ... Full story

Genes linked to people’s bowel habits

A new publication in the scientific journal Gut sheds light on the role that certain genes have in determining how people differ in their bowel habits. The study results from the collaboration of research groups at Karolinska Institutet and the University Medical Centre Groningen, Groningen, the Netherlands. ... Full story

Codependence of Cell Nucleus Proteins Key to Understanding Fatty Liver Disease

Penn study sheds light on biology of leading cause of liver failure ... Full story

Fighting life-threatening bacteria without antibiotics

Researchers at the University of Bonn and the Technical University of Munich discover the cause of infections in patients with cirrhosis of the liver. Patients suffering from liver cirrhosis often die of life-threatening bacterial infections. In these patients the immune cells are unable to eliminate the bacterial infections. Scientist at the University of Bonn and TU Munich have now discovered that type I IFN released by immune cells due to increased migration of gut bacteria into the cirrhotic liver incapacitate the immune system. Based on their findings, such life-threatening infections can be contained by strengthening the immune response alone – without antibiotics. The results have now appeared in the journal "Gut". ... Full story

The colon is defended from bacteria by a self-sacrificing sentinel cell

A lone Sentinel cell monitors and coordinates the defense of the entrance to the colon’s most sensitive parts. The Sentinel cell detects nearby bacteria and signals to a line of defensive cells to send out a cascade of mucus to push away the invaders. As a final self-sacrificing action the cell commits suicide and ejects itself into the intestinal lumen. ... Full story

Veggie juice that illuminates the gut

The medical imaging drink, developed to diagnose and treat gastrointestinal illnesses, is made of concentrated chlorophyll, the pigment that makes spinach green ... Full story

Professor’s research demonstrates link between gut bacteria and brain inflammation in chronic liver disease

Jasmohan Bajaj, M.D., associate professor at Virginia Commonwealth University, had findings from his research on gut bacteria in cirrhosis published recently in the journals Hepatology and Scientific Reports. ... Full story

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