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Digestive System

Unlocking secrets of the immune system could help combat colitis

Researchers have unlocked secrets of our ancient immune system, a major scientific advance which could help scientists and clinicians in the global ...

Disruption of Intestinal Fungi Leads to Increased Severity of Inflammatory Disease

Fungi that live in a healthy gut may be as important for good health as beneficial intestinal bacteria, according to new research ...

UNC researchers help create key diagnostic measures for gastrointestinal disorders

UNC School of Medicine faculty members took on critical roles in amending diagnostic criteria questionnaires for functional GI disorders, which affect millions of people worldwide. ... Full story

Childhood antibiotic treatments reduce diversity and stability of intestinal microbiota

Repeated antibiotic treatments administered during early childhood promote the multiplication of antibiotic resistant bacteria. ... Full story

UC Davis study finds antibiotics increase availability of nutrients in the gut, enabling growth of pathogens

SACRAMENTO, Calif.) — Researchled by Andreas Bäumler, professor of medical immunology and microbiology at UC Davis Health System, has identified a new mechanism explaining how antibiotics change the gut microbiota, increasing nutrients that benefit the growth of pathogens, like Salmonella. ... Full story

Unraveling the food web in your gut

Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under investigated. Using a manually curated metabolic module framework for (meta-)genomic data analysis, Sara Vieira-Silva, Gwen Falony and colleagues from the Jeroen Raes lab (VIB/KU Leuven) studied species-function relationships in gut microbial genomes and microbiomes. The team of the Flemish Gut Flora Project observed that half of the bacteria in the human gut were metabolic generalists, while others were specializing and feeding on specific substrates, such as carbohydrates, proteins, or lipids. ... Full story

Researchers Convert Cirrhosis-Causing Cells to Healthy Liver Cells in Mice

New Approach That Repairs Liver from Within May Be More Efficient Than Cell Transplants ... Full story

Specialty care improves liver disease survival

Access to health care for veterans with liver disease is highlighted as study links specialists to better outcomes ... Full story

Gut Flora may lead to better diagnosis tool for liver disease and this opens new avenues for treatment

Primary sclerosing cholangitis, also known as PSC, is a liver disease with no effective medical treatment. Liver transplantation is the only proven long-term treatment of PSC, although only a fraction of individuals with PSC will ultimately require it. The vast majority of patients with PSC also have inflammatory bowel disease (Crohn’s disease or ulcerative colitis), possibly implying that the intestine plays a role in the origin of this PSC. Researchers from VIB, UZ Leuven and KU Leuven now describe for the first time how changes in the intestinal microbiota are specifically associated with this disease. ... Full story

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