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Institute of Food Research helps combat serious gut infections

A new treatment programme for Clostridium difficile (C. diff) is being announced this week during International Infection Prevention Awareness Week 17-21 October. ...

Genome study identifies risk genes in African Americans with inflammatory bowel disease

In the first genome-wide association study (GWAS) of genetic risk factors for inflammatory bowel disease in African Americans, a research team has ...

New receptors discovered for stomach germ Helicobacter pylori

Helicobacter pylori is a spiral bacterium that can colonize the human stomach – sometimes with fatal consequences. A research group led by Prof. Markus Gerhard of the Technical University of Munich (TUM) and Assistant Professor Dr. Bernhard B. Singer of the Institute for Anatomy at the Faculty of Medicine of the University of Duisburg-Essen at Essen University Medical Centre has discovered a completely new approach to preventing or treating infections with this bacterium as well as secondary complications. This research was done in collaboration with the group of Prof. Han Remaut (VIB – VUB, Belgium). “Nature Microbiology”, a scientific journal, reports on this in its current edition. ... Full story

EGF receptor found to regulate macrophage inflammation in gut

Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract. ... Full story

Hormone identified that limits liver fibrosis - Potential applications for treating nonalcoholic steatohepatitis, cirrhosis

Nonalcoholic steatohepatitis (NASH) has been emerging worldwide and effective treatment, especially for liver fibrosis, is essential for improving the prognosis. A Japanese research team has identified and clarified the mechanism for a hormone that limits the fibrosis associated with NASH and cirrhosis. This discovery has potential applications for the treatment of these conditions. These findings were published on October 10 in the online version of Scientific Reports. ... Full story

Technique May Identify Patients with Fast-Progressing Fibrosis in Nonalcoholic Fatty Liver Disease

Earlier, more nuanced diagnoses would benefit patients with common condition that can develop into cirrhosis and liver cancer ... Full story

Study explains how an intestinal microbe protects against other, more dangerous bacteria

  Science News   Bad stomach: The researchers performed experiments in C. elegans worms infected with Salmonella bacteria. In this cross section of a worm, the rod-shaped microbes ... Full story

New research delimits the possible causes of celiac disease

The amount of gluten could be a more important clue than breast-feeding or the timing of the introduction of gluten for continued research into the causes of celiac disease (gluten intolerance). This is one of the findings from several extensive studies of children with an increased genetic risk of celiac disease conducted by researchers at Lund University in Sweden. ... Full story

Bile acid uptake inhibitor prevents NASH/fatty liver in mice

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children’s Healthcare of Atlanta have shown. ... Full story

Gut pathogens thrive on body's tissue-repair mechanism

(SACRAMENTO, Calif.) — Why do some foodborne bacteria make us sick? A paper published Sept. 16 in the journal Science has found that pathogens in the ... Full story

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