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Immune System

Researchers find more uses for immune system's 'Swiss army knife'

Oxford University research has found that a little-studied and relatively unknown part of the human immune system could be twice as important ...

An unexpected origin for calming immune cells in the gut

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit ...

E-cigarette use can alter hundreds of genes involved in airway immune defense

The long-term health effects of e-cigarettes remain unknown, but toxicologists at UNC are now uncovering how use of e-cigarettes affect genes involved in upper airway immune defense. ... Full story

Microbiota affect the rate of transplant acceptance and rejection

Mouse study shows the composition of microbes on the body influences the immune response against transplanted tissue ... Full story

The impact of night work on our immune system

Study reveals the impact of night work ... Full story

Cancer drugs could target autoimmune diseases

Drugs currently being trialled in cancer patients have been used to successfully target an autoimmune condition in mice at UCL and King’s College London. ... Full story

Natural killer cells have a memory

Researchers at the University of Bonn and the Ludwig-Maximilians-Universität of Munich have decoded a new mechanism of how the immune system can specifically attack pigmented cells of the skin. It was previously believed that so-called natural killer cells did not have an immunological memory for the body's own tissues. However, the scientists have now been able to show that these special immune cells can indeed “remember” pigmented cells when they come into more frequent contact with a specific contact allergen. These results may provide new insights into the development of the skin-depigmenting disease vitiligo but may also offer new options for the treatment of malignant melanoma. These results have now been published in the renowned scientific journal “Immunity”. ... Full story

New clues found to immune system’s misfiring in autoimmune diseases

Gene variants mapped to DNA regions that regulate immune cells ... Full story

Regulation of semiochemicals in inflammation

Team from Kiel's Cluster of Excellence "Inflammation at Interfaces" discovers fundamental new mechanism ... Full story

A New Look at Caspase 12 Research

Inflammasomes are assemblies that are central to inflammatory responses. Dr. Lieselotte Vande Walle, Daniel Jiménez Fernández and colleagues from Prof. Mo Lamkanfi’s group (VIB/UGent) shed new light on the function of caspase 12. In doing so, they have rid the field of a stubborn dogma, which held that caspase 12 was a negative regulator of inflammasomes. These novel insights pave the way for researchers to break from the route of existing research and identify the real physiological functions of caspase 12. ... Full story

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