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Immune System

Does Freeze-Thawing and IV Delivery Affect the Therapeutic Potential of Mesenchymal Stromal Cells?

New Rochelle, NY — Before the therapeutic potential of using human tissue-derived mesenchymal stromal cells (MSC) to treat immune and degenerative diseases ...

Cytokine Triggers Immune Response at Expense of Blood Renewal

Research Highlights Promise of Anti-IL-1 Drugs to Treat Chronic Inflammatory Disease ...

Scientists solve immune system mystery for Type 1 diabetes

Scientists have solved a decades-old medical mystery by finally identifying a previously unknown molecule which is attacked by the immune system in people with Type 1 diabetes. ... Full story

Yale study suggests that immune response to flu causes death in older people, not the virus

By Ziba Kashef - A new Yale-led study suggests that death from influenza virus in older people may be primarily caused by a damaging immune response to flu and not by the virus itself. The insight could lead to novel strategies for combating flu in the most vulnerable patients, said the researchers. ... Full story

Brain’s Immune System Triggers Frontotemporal Dementia

Research Suggests Disease Mechanism, Therapeutic Approach for Early-Onset Dementia ... Full story

World Immunization Week 2016: Immunization game-changers should be the norm worldwide

Geneva - During World Immunization Week 2016, held 24-30 April, WHO highlights recent gains in immunization coverage, and outlines further steps countries can take to “Close the Immunization Gap” and meet global vaccination targets by 2020. ... Full story

Cpf1: CRISPR-enzyme scissors cutting both RNA and DNA

Scientists delineate molecular details of a new bacterial CRISPR-Cpf1 system and open possible avenue for alternative gene editing uses like targeting several genes in parallel ... Full story

Inflammatory Protein Involved in Autoimmune Diseases Has Healing Potential

Production of immune surveillance cells (M cells) plays key therapeutic role in diseases like inflammatory bowel disease, multiple sclerosis and type 1 diabetes ... Full story

Research paves the way for monocyte based cell therapy

​ Researchers from VIB-UGent reveal that adult circulating monocytes that get access to the macrophage niche in the liver or the lung can acquire identical tissue-specific macrophage functions and self-maintenance capacities as macrophages of embryonic origin. This paves the way towards monocyte-based cellular therapy in diseases associated with macrophage dysfunction, such as the disease known as pulmonary alveolar proteinosis. Using a mouse model for pulmonary alveolar proteinosis, the authors demonstrate that this rare disease can be cured by a single transfer of monocytes. ... Full story

Study ties recently discovered immune cell to disease

Deficits in a recently discovered immune cell’s function may trigger a rare age-related auto-inflammatory disease — and perhaps far more common ones, too. ... Full story

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