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Immune System

Study finds 'double-crossing' protein could hinder disease therapies

A protein known for guarding against viral infections leads a double life, and can interfere with cell growth and the defence against ...

New gene defect for SCID identified

Severe combined immunodeficiency or SCID is one of the most devastating immunological conditions. Babies are born without functional immune systems, especially low ...

EBV-derived microRNAs silence immune alarm signals of the host cell

Epstein-Barr virus (EBV) prevents infected cells from being attacked by the immune system. The virus drives production of small molecules, so-called microRNAs, that suppress alarm signals sent out by the infected cell. Scientists at Helmholtz Zentrum München have elucidated this previously unknown mechanism. ... Full story

Gut dysfunction impacts our wellbeing

A major study at Victoria University is uncovering why gut dysfunction impairs the immune system and how it can affect mood and cognition. ... Full story

Scientists discover how insect-borne viruses ‘suppress’ the immune system to cause disease

Arboviruses – viruses transmitted by insects such as mosquitoes – pose a considerable threat to both human and animal health. Despite that, not enough is known about the complex interactions between the virus and the host, particularly in the early stages of infection. ... Full story

Scientists make major breakthrough in understanding inflammation

• The action of cells that spark inflammation causes a ‘re-wiring’ of their mitochondria, which amplifies the inflammation response • Targeting the cells responsible for the initial spark may keep the process under control and offer new treatment options for a host or inflammatory diseases ... Full story

Tattoo therapy could ease chronic disease

Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases ... Full story

Molecular Switch Controlling Immune Suppression May Help Turn Up Immunotherapies

Discovery could broaden effectiveness of emerging therapies for cancer and other diseases that are based on boosting the natural immune system response ... Full story

Immune system plays major role in regulation of body weight

Trinity academic part of new research which reveals that the immune system could be responsible for as much as 40% of our body’s ability to regulate weight. ... Full story

One more reason to swear off tobacco: The inflammatory trap induced by nicotine

An Umeå-based team in collaboration with US researchers reveals a new link between nicotine and inflammation. They report that nicotine strongly activates immune cells to release DNA fibres decorated with pro-inflammatory molecules, so called neutrophil extracellular traps (NETs). The continuous exposure to these NETs can harm the tissue and could explain the hazardous consequences of tobacco consumption for human health. ... Full story

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