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Male Reproductive

Defective sperm ‘rescued’ in fertility treatment study

Researchers use ‘kick-starter’ protein to trigger fertilization in mouse models ...

NUS team discovers novel way of protecting male reproductive cells and hails new approach to addressing male infertility

Study demonstrated a potential avenue to protect male germ cells against heat stress by applying an external source of hydrogen sulphide ...

Penn Team Identifies Gene Responsible for Some Cases of Male Infertility

In the most severe form of male infertility, men do not make any measurable levels of sperm. This condition, called azoospermia, affects approximately 1 percent of the male population and is responsible for about a sixth of cases of male infertility. ... Full story

Sperm Meets Egg: New Reproductive Research Could Lead to Male Contraceptive

Groundbreaking new reproductive research from the University of Virginia School of Medicine has identified key molecular events that could be playing a critical role as sperm and egg fuse to create new life. The findings might one day lead to the creation of a male contraceptive. ... Full story

Discovery of a Protein Capable of Regulating DNA Repair During Sperm Formation

UAB researchers have discovered that the inhibition of a protein, called ATM, could foster the appearance of genetic anomalies during the process of spermatogenesis. The inhibition of this protein could generate fertility problems. The research was published recently in PLOS Genetics. The research has been published in PLOS Genetics. ... Full story

Decline in the number of males involved in reproduction during the period of global growth

Wealth and power may have played a stronger role than “survival of the fittest”. ... Full story

Physical labor, hypertension and multiple meds may reduce male fertility

NIH-funded study analyzes data from more than 450 men attempting to conceive ... Full story

Penn Scientists Describe the Function of an Enzyme Critical to Male Fertility

Researchers are one step closer to unraveling the extraordinarily complex series of processes that lead to an event crucial to human reproduction: the creation of sperm. ... Full story

New research may provide insight into reasons behind male infertility

Virginia Commonwealth University School of Medicine researchers have identified a protein complex that is essential for formation of the sperm tail — findings that could lead to novel approaches to male contraception and clarify some of the unknown factors that contribute to male infertility. ... Full story

Mutation may cause early loss of sperm supply

Problems in a gene responsible for producing the protein TAF4b leave mice — and maybe men — unable to sustain sperm production. As embryos, mice lacking the protein failed to develop an adequate number of key cells in the sperm production process and as adults they quickly lost their initial fertility. ... Full story

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