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Male Reproductive

Discovery of a Protein Capable of Regulating DNA Repair During Sperm Formation

UAB researchers have discovered that the inhibition of a protein, called ATM, could foster the appearance of genetic anomalies during the process ...

Decline in the number of males involved in reproduction during the period of global growth

Wealth and power may have played a stronger role than “survival of the fittest”. ...

Physical labor, hypertension and multiple meds may reduce male fertility

NIH-funded study analyzes data from more than 450 men attempting to conceive ... Full story

Penn Scientists Describe the Function of an Enzyme Critical to Male Fertility

Researchers are one step closer to unraveling the extraordinarily complex series of processes that lead to an event crucial to human reproduction: the creation of sperm. ... Full story

New research may provide insight into reasons behind male infertility

Virginia Commonwealth University School of Medicine researchers have identified a protein complex that is essential for formation of the sperm tail — findings that could lead to novel approaches to male contraception and clarify some of the unknown factors that contribute to male infertility. ... Full story

Mutation may cause early loss of sperm supply

Problems in a gene responsible for producing the protein TAF4b leave mice — and maybe men — unable to sustain sperm production. As embryos, mice lacking the protein failed to develop an adequate number of key cells in the sperm production process and as adults they quickly lost their initial fertility. ... Full story

WSU researchers see effect of BPA and Estradiol on sperm development

PULLMAN, Wash.—Washington State University researchers have found a direct link between the plastics component bisphenol A, or BPA, and disrupted sperm production. Writing in the journal PLOS Genetics, they say the chemical disrupts the delicate DNA interactions needed to create sperm. ... Full story

Egg and sperm race: Scientists create precursors to human egg and sperm

Scientists at the University of Cambridge working with the Weizmann Institute have created primordial germ cells – cells that will go on to become egg and sperm – using human embryonic stem cells. Although this had already been done using rodent stem cells, the study, published today in the journal Cell, is the first time this has been achieved efficiently using human stem cells. ... Full story

Stunning Zinc Fireworks When Egg Meets Sperm

Understanding of zinc’s role in healthy embryos could improve in vitro fertilization ... Full story

Poor semen quality linked to hypertension, other health problems, study finds

A study of men who were evaluated for the cause of their infertility finds previously unknown relationships between deficiencies in their semen and other, seemingly unrelated health problems. ... Full story

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