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Medical Breakthroughs

Structure from Disorder: Scripps Research Institute Scientists Find New Source of Versatility so ‘Floppy’ Proteins Can Get Things Done

LA JOLLA, CA – Many proteins work like Swiss Army knives, fitting multiple functions into their elaborately folded structures. A ...

3-D printing could lead to tiny medical implants, electronics, robots, more

BOSTON — 3-D printing now can be used to print lithium-ion microbatteries the size of a grain of sand. The printed microbatteries ...

Pioneering breakthrough of chemical nanoengineering to design drugs controlled by light

Researchers at IRB Barcelona and IBEC achieve photo-switchable molecules to control protein-protein interactions in a remote and non-invasive manner. ... Full story

New way to improve antibiotic production

An antibiotic has been found to stimulate its own production, a discovery which could make it easier to scale up antibiotic production for commercialisation. ... Full story

Penn Researchers Design Variant of Main Painkiller Receptor

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor. ... Full story

Penn Research Team Designs Novel Variant of Main Painkiller Receptor

PHILADELPHIA — University of Pennsylvania researchers from a multidisciplinary team from the Department of Anesthesiology and Critical Care, Perelman School of Medicine and the Department of Chemistry, School of Arts and Sciences, have developed a soluble variant of the mu opioid receptor, which is involved in pain and addiction, that may facilitate the development of novel pain medications. Their findings appear in the latest edition of the journal PLOS ONE. ... Full story

New Findings Regarding DNA Damage Checkpoint Mechanism in Oxidative Stress

CHARLOTTE, N.C. - In current health lore, antioxidants are all the rage, as “everybody knows” that reducing the amount of “reactive oxygen species” -- cell-damaging molecules that are byproducts of cellular metabolism -- is critical to staying healthy. What everyone doesn’t know is that our bodies already have a complex set of processes built into our cells that handle these harmful byproducts of living and repair the damage they cause. ... Full story

CSHL geneticists solve mystery of EEC Syndrome's variable severity in children

Proteins called TAp63 act as genetic modifiers in an illness that produces cleft palate and major deformities of limbs, skin ... Full story

Testing method promising for spinal cord injuries, multiple sclerosis

WEST LAFAYETTE, Ind. - A medical test previously developed to measure a toxin found in tobacco smokers has been adapted to measure the same toxin in people suffering from spinal cord injuries and multiple sclerosis, offering a potential tool to reduce symptoms. ... Full story

UC Santa Barbara Researchers Identify the Mechanisms Underlying Salt-Mediated Behaviors in Fruit Flies

(Santa Barbara, Calif.) –– Next time you see a fruit fly in your kitchen, don't swat it. That fly could have a major impact on our progress in deciphering sensory biology and animal behavior, including someday providing a better understanding of the human brain. ... Full story

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