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Medical Breakthroughs

Study explains why our organs are bendy

An international team of researchers has discovered how one of the body’s crucial building blocks allows human tissues to be so flexible. ...

Ischemic renal failure and organ damage: a new mouse model holds the key

The activation of NF-kB over time is depicted in a rainbow colour scheme. 2-3 days after ischemia it reaches a maximum, then ...

New method for detecting and preserving human stem cells in the lab

Human stem cells that are capable of becoming any other kind of cell in the body have previously only been acquired and cultivated with difficulty. A team of European scientists including researchers from the University of Bath has now developed a method to detect such pluripotent cells in a cell culture and preserve them in the laboratory. ... Full story

New Stem Cell Model Valuable Tool for Studying Andersen’s Syndrome

New Rochelle, NY —Successful reprogramming of muscle cells derived from biopsies of patients with Andersen's syndrome (AS) led to the formation of induced pluripotent stem (iPS) cells that can serve as a valuable model for understanding the cause of this rare disorder and discovering novel therapies. Details of the methods used to generate the AS-iPS cells and evidence of their capacity for self-renewal and pluripotency are presented in the study published in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. ... Full story

Researchers Shed New Light on Regulation of Repetitive DNA Sequences

A pair of studies by a team of scientists has shed new light on the nature of a particular type of DNA sequences—tandem DNA repeat arrays—that play important roles in transcription control, genome organization, and development. ... Full story

Piecing together the cells “elevator-like” mechanism for sodium

Researchers from Stockholm University have pieced together how sodium is transported into and out of our cells. ... Full story

Protein Critical to Cell Survival Also Promotes Metastasis Independently

A protein that normally exists in the mitochondria of healthy cells appears to travel to the nucleus of cancer cells and promote metastasis, according to new research from Weill Cornell Medicine investigators. ... Full story

Link Between Environmental Toxin and ALS Grows Stronger

“I lose a patient every couple of weeks from the disease, and I see the devastating effects it has on patients and families—it’s very sad,” says Elijah Stommel, MD, PhD, a professor of neurology at Dartmouth’s Geisel School of Medicine and a neurologist at Dartmouth-Hitchcock Medical Center. ... Full story

Faster drug discovery?

Startup develops more cost-effective test for assessing how cells respond to chemicals. ... Full story

TSRI Study Reveals Workings of Mysterious 'Relief Valve' that Protects Cells from Swelling

LA JOLLA, CA —A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job. ... Full story

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