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Medical Breakthroughs

Introducing the multi-tasking nanoparticle

Versatile particles offer a wide variety of diagnostic and therapeutic applications ...

Revolutionary handheld DNA diagnostic unit allows lab-quality analysis in the field

The Freedom4 development team: (L-R) Ms Christy Rand, Mr Chris Mason, Dr Chris Rawle and Dr Jo-Ann Stanton. Credit: Sharron Bennett ...

Making of Mirror-Image Protein Has Applications for Drug Discovery, Synthetic Biology

(SALT LAKE CITY)–University of Utah biochemists have reported an advance in the production of functional mirror-image proteins. According to a groundbreaking study published in this week’s online edition of PNAS, they have chemically synthesized a record-length mirror-image protein and used this protein to demonstrate that a cellular chaperone, which helps “fold” large or complex proteins into their functional state, has a previously unappreciated talent – the ability to fold mirror-image proteins. ... Full story

Biologists Reprogram Skin Cells to Mimic Rare Disease

Additional tool accelerates personalized medicine research ... Full story

Conclusive Evidence on Role of Circulating Mesenchymal Stem Cells in Organ Injury Presented in Stem Cells and Development

New Rochelle, NY — Mesenchymal stem cells (MSCs) are present in virtually every type of human tissue and may help in organ regeneration after injury. But the theory that MSCs are released from the bone marrow into the blood stream following organ damage, and migrate to the site of injury, has long been debated. M.J. Hoogduijn and colleagues provide conclusive evidence to resolve the controversy over the mobilization and migration of MSCs in humans in a new study published in Stem Cells and Development, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. ... Full story

Tissue regeneration using anti-inflammatory nanomolecules

Anyone who has suffered an injury can probably remember the after-effects, including pain, swelling or redness. ... Full story

Scientists discover thymus stem cells

Scientists at the German Cancer Research Center (DKFZ) have identified a common progenitor of cortical and medullary thymic epithelial cells ... Full story

Encyclopedia of stem cells – Identification of regulatory networks in hematopoietic stem cells and their immediate progeny

In this study, scientists from the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL) present integrated quantitative proteome, transcriptome and DNA-methylome analyses of hematopoietic stem cells (HSCs) and four multipotent progenitor (MPP) populations. ... Full story

First clinical trial for new skin wound-healing compound is a success

ROANOKE, Va – Virginia Tech Carilion Research Institute scientist Robert Gourdie developed a wound-healing peptide while researching how electrical signals trigger heartbeats. He never imagined that the peptide, ACT1, would prove to heal venous leg ulcers twice as quickly as the current standard of care. ... Full story

Stem Cell Therapies Hold Promise, But Obstacles Remain

In an article appearing online today in the journal Science, a group of researchers, including University of Rochester neurologist Steve Goldman, M.D., Ph.D., review the potential and challenges facing the scientific community as therapies involving stem cells move closer to reality. ... Full story

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