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Medical Breakthroughs

Somatic stem cells obtained from skin cells for first time ever

Skipping pluripotency 'detour,' Max Planck researcher Prof. Schöler again takes lead in stem cell research
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Understanding the double-edge sword of steroids

by Marketing and Communications - Glucocorticoids are a type of steroid hormone that are used to treat everything from asthma to arthritis, but the impact of these powerful anti-inflammatory drugs – particularly in prolonged, low-doses – remains to be fully understood....
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Study of ribosome evolution challenges RNA world hypothesis

CHAMPAIGN, lll. — In the beginning – of the ribosome, the cell’s protein-building workbench – there were ribonucleic acids, the molecules we call RNA that today perform a host of vital functions in cells. And according to a new analysis, even before the ribosome’s many working parts were recruited for protein synthesis, proteins also were on the scene and interacting with RNA. This finding challenges a long-held hypothesis about the early evolution of life....
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Team discovers how bacteria resist a 'Trojan horse' antibiotic

CHAMPAIGN, lll. — A new study describes how bacteria use a previously unknown means to defeat an antibiotic. The researchers found that the bacteria have modified a common “housekeeping” enzyme in a way that enables the enzyme to recognize and disarm the antibiotic....
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Study Suggests Possible Therapeutic Use for 'Bath Salt' Designer Drugs

Madison, Wisconsin - The non-medical use of "designer drugs" is on the rise worldwide, but little is known about how the psychoactive compounds actually affect the brain....
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Structure of ‘Salvia’ receptor solved

A research team has determined the structure of the kappa-opioid receptor — site of action of the widely abused hallucinogen Salvia divinorum – solving longstanding scientific mysteries and offering new insights for treating drug addiction, chronic pain and depression. ...
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Perelman School of Medicine Experts Identify Inhibitor Causing Male Pattern Baldness and Target for Hair Loss Treatments

PHILADELPHIA — Researchers from the Perelman School of Medicine at the University of Pennsylvania have identified an abnormal amount a protein called Prostaglandin D2 in the bald scalp of men with male pattern baldness, a discovery that may lead directly to new treatments for the most common cause of hair loss in men. ...
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Structure of Disease-Causing Amyloid Protein Solved

Novel Protein Structure at Heart of Toxic Amyloids...
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Powerful new cells cloned

Powerful new cells created by Cardiff scientists from cheek lining tissue could offer the answer to disorders of the immune system....
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