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Research suggests that diabetes could be due to failure of beta cell 'hubs'

The significant role of beta cell ‘hubs’ in the pancreas has been demonstrated for the first time, suggesting that diabetes may due ...

Breastfeeding alters maternal metabolism and protects against diabetes for up to 15 years after delivery

Neuherberg - An interdisciplinary team of scientists at the Helmholtz Zentrum München has studied the metabolism of women with gestational diabetes after ...

Eating more healthy fats in place of either carbs or saturated fats improves risk factors for type 2 diabetes

A large-scale meta-analysis finds consumption of unsaturated fats in place of either saturated fats or carbohydrates could aid in the prevention and management of type 2 diabetes ... Full story

Antibodies may have role in preventing Type 1 diabetes

People with a rare autoimmune disorder produce autoimmune antibodies that appear to be linked to a reduced occurrence of Type 1 diabetes, new research has found. The study, published in Cell, suggests these antibodies could limit immune-related diseases and may have therapeutic potential. ... Full story

New guidelines on diabetes in children admirable - but need adequate resourcing, says College

RCGP Diabetes Lead, Dr Stephen Lawrence, has responded to new NICE guidance on diabetes in children and young people. ... Full story

When genes fail to respond

Neuherberg/Tübingen. It is widely accepted that physical exercise lowers the risk of developing diabetes. Yet in one in five participants in related studies this positive effect fails to materialize. Researchers and clinicians involved in a collaborative translational project launched by the German Center for Diabetic Research between the Helmholtz Zentrum München and the University Hospital Tübingen have now discovered what occurs in the muscle of these so-called “non-responders”. The results of their research were published recently in the Diabetes journal. ... Full story

New Diabetes Screening Recommendation Misses More than Half of High-Risk Patients

Widely accepted screening guidelines don’t identify many patients with diabetes and prediabetes ... Full story

Discovery could lead to treatment to better regulate insulin

AMES, Iowa – Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don’t always work for those who are obese or diabetic, and most need to regulate their glucose and insulin levels. That’s why a recent discovery made by Rudy Valentine and a team of researchers holds so much promise. ... Full story

New Approach for Regenerative Therapy

Neuherberg - The marker Flattop subdivides the insulin-producing beta cells of the pancreas into those that maintain glucose metabolism and into immature cells that divide more frequently and adapt to metabolic changes. This could provide a starting point for regenerative diabetes therapies, as scientists of Helmholtz Zentrum München, in collaboration with colleagues of the Technical University of Munich and the German Center for Diabetes Research (DZD), report in the journal ‘Nature’. ... Full story

U-M, international research team explore genetic architecture of type 2 diabetes

ANN ARBOR—New research from a large international team of scientists offers a more complete picture of the genes responsible for type 2 diabetes, demonstrating that previously identified common alleles shared by many in the world are the biggest culprits—not the less common variants some scientists had hypothesized might play a large role in who gets the disease. ... Full story

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