ROCHESTER, Minn. — The resurgence of exercise has been accompanied by multiple supplements, sports drinks, and energy beverages that promise to enhance performance, muscle growth, and recovery. But the question remains: Are energy beverages safe?

"One can of an energy beverage during one session of exercise is safe for most healthy individuals," says John Higgins, M.D., lead author from The University of Texas Medical School in Houston. However, he states, "excess consumption and consumption with other caffeine-containing beverages or alcohol may lead to adverse effects and possibly death."

The United States is the world's largest consumer of energy beverages by volume, and consumption is primarily among people ages 11 to 35 years. The most common ingredient is caffeine, which ranges from 50 milligrams (mg) to 505 mg per 16-ounce serving.

A peer-reviewed journal, Mayo Clinic Proceedings publishes original articles and reviews dealing with clinical and laboratory medicine, clinical research, basic science research and clinical epidemiology. Mayo Clinic Proceedings is published monthly by Mayo Foundation for Medical Education and Research as part of its commitment to the medical education of physicians. The journal has been published for more than 80 years and has a circulation of 130,000 nationally and internationally. Articles are available online.

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