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H-Proof Hangover Pills Reviews 2022: Do Hangover Cures Work?

Cassi Donegan

Updated on - Written by
Medically reviewed by Dr G. Michael DiLeo, MD

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  • Featured in Forbes, Medical Daily, and The Skimm
  • Founded by a board-certified surgeon
  • Promotes liver health
  • Supports alcohol metabolism
  • Zero caffeine
  • Supports the immune system
  • Helps to maintain electrolyte balance
  • Scientifically supported ingredients

Brand Information

  • Founded by Linda Kaplan MD and her daughter
  • Featured in Forbes

Medical Benefits

  • Promotes liver health
  • Restores essential nutrients
  • Helps metabolize alcohol
  • Reduces hangover symptoms

About The Brand

Linda Kaplan, MD, and her daughter Rachel launched their first product from their company, Kaplan Labratory LLC, in 2019. Linda is a board-certified surgeon who combines scientific research with her medical expertise to promote liver health and reduce hangover symptoms with a patented nutraceutical by the name of H-proof.

What Is H-Proof?

H-Proof is a hangover pill that Kaplan claims is backed by science. This company claims their “anytime you drink vitamin” can promote alcohol metabolism by enhancing the body’s ability to create the enzymes the liver needs to turn too much alcohol into something harmless. 

Hangover symptoms in the human body can look like this:

  • Headache 
  • Excessive thirst
  • Dizziness
  • Mental fogginess
  • Nausea, vomiting, stomach pain
  • Fatigue and weakness
  • Muscle aches
  • Light and sound sensitivity 
  • Sleeplessness 
  • Shakiness
  • Mood disturbances

Acetaldehyde[1], a metabolite of alcohol, is inflammatory to the liver, pancreas, brain, intestinal tract, among other organs. This supports H-proof’s claims that it’s not dehydration that causes the hangover, but the liver’s inability[2] to create all the enzymes it needs to flush out the toxins from alcohol use. Taking H-proof is supposed to help you 

  • Maintain your liver health
  • Restore vital nutrients your body needs
  • Wake in the morning feeling refreshed

Let’s look at H-proof reviews and ingredients to see if this product may accomplish all its claims.

Feature Product & Coupon


Best Reputation


  • Featured in Forbes, Medical Daily, and The Skimm
  • Founded by a board-certified surgeon
  • Promotes liver health
  • Supports alcohol metabolism
  • Zero caffeine
  • Supports the immune system
  • Helps to maintain electrolyte balance
  • Scientifically supported ingredients

Does H-Proof Work?

As people age, their metabolism tends to slow down, and when it does, they make fewer liver enzymes to process and break down the alcohol they drink, resulting in hangovers. H-proof claims their ingredients formula promotes these liver enzymes that turn an alcoholic drink from a toxin into a harmless substance, helping you to feel better the morning after.

While this product does not contain stimulants like caffeine, it has many vitamins, minerals, and antioxidants[3] that help to boost the immune system, liver function, and fight off free radicals that cause damage to cells. 

So is H-proof a hangover cure? Some people swear in H-proof reviews that this supplement eliminates their typical hangover, while others say it reduces their symptoms. Then there are the few people who report no change in how they feel after a night of drinking. 


  • 30-day 100% money-back guarantee 
  • Promotes liver health
  • Provides essential nutrients
  • May reduce hangover symptoms
  • May be beneficial when not drinking
  • Three flavors available 
  • Zero caffeine 


  • Contains sucralose
  • Must chew it up
  • Several dollars per serving

H-Proof Ingredients 

H-proof is a patented hangover formula that is vegan and gluten-free. It contains over 12 vitamins and minerals that can benefit overall health, like vitamin C and zinc, which help support the immune system. This multivitamin also contains potassium, magnesium, and sodium to help hydrate and maintain the body’s electrolyte balance. H-proof has zero calories and carbohydrates. 

Some of the vitamin doses in H-Proof’s ingredient formula are a much higher value than the daily recommended intake. For example, the B12 (methylcobalamin) contains 16.8 micrograms of vitamin B12 or 700% of the daily value. The B vitamins in H-Proof are to promote the enzymes that power alcohol metabolism.  

The two tablets in each dose of H-Proof contain a proprietary blend for liver support with four key ingredients to promote alcohol metabolism and promote liver health. Let’s look into these ingredients meant to restore vital nutrients and help with a hangover further.

H-Proof Ingredients

Dihydromyricetin (DHM)

DHM is also known as ampelopsin and comes from a Japanese raisin tree fruit. It may be a helpful flavanol in protecting against severe alcohol intoxication. This active ingredient found in H-proof may help power alcohol metabolism by triggering the liver[4] to promote more helpful enzymes so the body can flush the toxins from its system more efficiently. 

This herbal remedy may also help to flush alcohol[5] out of the body faster than normal. While its use as a liver remedy has continued for hundreds of years, studies are still ongoing to understand precisely how it works.  

Milk Thistle

Milk thistle is a natural herbal remedy that is popular to help prevent and cure a hangover. It may help protect your liver and support alcohol metabolism. H-proof uses silymarin, an active compound from the milk thistle seed extract.

Silymarin helps the liver by acting as an antioxidant and helps to reduce inflammation. Some studies[6] suggest that it can help improve liver disease and help the organ detox from harmful substances. 


Taurine is one of the amino acids that naturally occur in the body, and studies show that taurine can significantly increase[7] the rate at which the liver eliminates alcohol from the body. This may be a valuable ingredient to help preserve liver function[8] and prevent liver injury.  

L-Glutathione And N-Acetyl Cysteine

The ingredient L-glutathione is in the liver support proprietary blend in the 20-serving bottle and the smaller, 10-count bottles. L-glutathione is not in the individual serving packets containing two H-proof tablets–that product has N-acetyl cysteine instead. However, it is not currently clear why they have two different formulas for their tablets. 

These two ingredients both support alcohol metabolism and may improve hangover symptoms[9]. Both of these are important ingredients for the body’s ability to eliminate toxins and remain strong. Not having enough glutathione[10] can increase your risk of liver disease and injury.

Alternatives To H-Proof

Liquid IV Hydration Multiplier

Liquid IV Hydration Multiplier

See Liquid IV Review

  • Helps to boost focus and concentration
  • Uses cellular transport technology
  • May enhance hydration
  • May reduce hangover symptoms
  • Expensive
  • 11 grams of sugar

Health Benefits Of H-Proof

Supports Your Immune System

Antioxidants in H-proof like vitamin C and silymarin help to increase the immune system’s ability to fight off cell damage and assist, along with ingredients like taurine[11], to reduce inflammation which can fight disease. 

Zinc[12] is an essential micronutrient that helps to grow healthy cells and restore cells that have been impaired by disease and infection. Glutathione is one of the body’s most important antioxidants for detoxing[13] and proper immune system functioning, and N-acetyl cysteine is necessary for its production. 

Supports Your Liver Function

DHM helps to reduce fat accumulation in the liver that arises from alcohol consumption, and it reduces inflammatory agents[14] that can damage organs from excessive alcohol use. It can also help the body eliminate alcohol faster by boosting enzyme potential.

Taurine and silymarin can also help reduce inflammation and may help reverse and prevent damage[15] done to the liver. Studies also show that folate and B12[16] may be a successful treatment against damage to the liver that drinking alcohol can cause. 

Potential Side Effects

The ingredients of H-proof are mostly natural vitamins and minerals. However, every human body is different, and you may be sensitive to one or more ingredients depending on your genetic makeup.

If you are taking medications or have a medical condition, talking to your healthcare provider before adding any new supplement to your regimen can benefit you. 


The serving size of this hangover pill is two chewable tablets. After your last drink and as soon as you’re able, it’s time to chew up the tablets one at a time and let them dissolve in your mouth.

If you have more than five drinks, the company recommends taking a full dose of H-proof and then, after any additional drinks, having another dose. It also suggests if you wake up and want to take more of these vitamins, to have another dose. 

H-Proof is advertised to be taken any time you drink, but also as a vitamin supplement that you can consume, even when not drinking, to receive its benefits.

H-Proof Reviews: What Do Real Users Say?

I have genuinely tried EVERY ‘hangover’ cure going, and none of them ever worked for me. I decided to try these on a whim, and I’m so glad I did because they absolutely do what they say they do. Do they cure your hangover entirely? No. Do they significantly decrease the negative effects of drinking the next day, meaning you can actually function and get things done? Yes, 100%. For anyone, like me, who has struggled with crippling hangovers all their life, I cannot recommend these tablets enough.


A group of us were at the beach and were all having several drinks throughout the day. We all used H-Proof and woke up the next morning feeling fine. No headache, nausea or general lethargic feeling you normally have after a night out. We were all surprised at how well it worked. I had gotten so sensitive to alcohol that I really couldn’t enjoy having an occasional drink or two with friends anymore. These vitamins are a game changer.


As a woman of a certain age, my beloved glass of red wine turned on me. A very common situation brought on by hormonal changes resulted in just a single glass leaving me with a headache. So saddened that even a glass or two in the evening didn’t seem possible anymore. Skeptical but longing for my wine, I tried h-proof. Queue up the harp music and angels singing. Thank you, H-proof, and honestly, I think the “H” should stand for hormone.


Whether it’s a bottle of wine with my husband or cocktails with friends, H-Proof allows me to get up early the next day and crush it. Seriously, I have workouts at 6:30 am and haven’t missed one, even if I drank the night before. Plus, it’s actually supporting my system in a lot of other great ways. Love it.


I find the H-Proof tablets do work pretty well, it seems. However, they are very sweet, like kids’ candy, which makes them hard to eat, especially at night. I wouldn’t recommend that the H-Proof chemists simply switch to another sweetener, rather, I would hope they would offer a less sweet version. I think then I would be rating the product at 4 or even 5 stars.

Mark W

I am so happy to be able to enjoy red wine and can finally sleep through the night with h-proof! I wake up well rested and don’t experience the sleep interruptions that I have always had.

Lara A.

I drank heavily, followed the recommendations on the bottle, and felt better than usual the next day. I still had some nausea and mental fogginess, but not nearly as much as without H-Proof.


Final Thought

H-Proof is a multivitamin that promotes a healthy liver and immune system, particularly for those with drinking habits or who have too much alcohol. This anytime-you-drink vitamin supplement claims to help your body metabolize alcohol, so you wake up the following day feeling refreshed from the restoration of vital nutrients you need for optimal health. 

Whether hangover cures personally work for you or not will require you to put them to the test. Make sure to read the ingredients, the instructions, and to drink responsibly. Making sure you eat a full, healthy meal, hydrate with healthy liquids, and drink your alcohol slowly will help you stick to your limits and give your body the best opportunity to wake up without a hangover. 

Frequently Asked Questions

When should I take the anytime-you-drink vitamin?

As soon as possible after your last drink.

How do I take H-Proof?

There are two tablets per serving. Chew each tablet up slowly and let it dissolve in your mouth before swallowing.

Can I use H-Proof when I’m not drinking?

The company suggests that yes, this is a safe product to use even when you’re not drinking. 

Can I dissolve it in water first?

No, this is a chewable. Absorption through the lining of the mouth and under the tongue is the mechanism recommended for getting H-Proof into your systems.

What does the anytime-you-drink vitamin taste like?

Lemonade is a sweet, but not too sweet, lemon flavor. Tangerine is said to be like eating Pez candy. The Black cherry taste compares to the flavor of Sweet Tarts candy.

Does H-proof help with hangovers?

H-proof ingredients can support the immune system, and electrolyte balance, and promote healthy liver function that may help with hangovers. The liver functions to clear alcohol from the system, so anything that enhances its function will help with hangovers.

What is the refund policy?

Within 30 days of your first purchase of 20 servings, you can get a full refund.

Does H-proof contain sugar?

H-proof claims it is a sugar-free product, but it uses sucralose for its ultra-sweet taste, which is a synthetic sweetener made from sugar. 

+ 16 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

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  4. USC News. (2020). Noted hangover remedy has added benefit of protecting the liver. [online] Available at: https://news.usc.edu/166789/hangover-remedy-dhm-liver-protection-usc-study/
  5. Shen, Y., Lindemeyer, A.K., Gonzalez, C., Shao, X.M., Spigelman, I., Olsen, R.W. and Liang, J. (2012). Dihydromyricetin As a Novel Anti-Alcohol Intoxication Medication. Journal of Neuroscience, [online] 32(1), pp.390–401. doi:10.1523/jneurosci.4639-11.2012.
  6. Vargas-Mendoza, N. (2014). Hepatoprotective effect of silymarin. World Journal of Hepatology, [online] 6(3), p.144. doi:10.4254/wjh.v6.i3.144.
  7. Ward, R.J. (2001). Taurine modulates catalase, aldehyde dehydrogenase, and ethanol elimination rates in rat brain. Alcohol and Alcoholism, [online] 36(1), pp.39–43. doi:10.1093/alcalc/36.1.39.
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Cassi Donegan

Medically reviewed by:

Michael DiLeo

Cassi Donegan, Licensed Practical Nurse, is a freelance health writer and editor. She has over 17 years of nursing experience in various specialties including Neurology, Orthopedics, Spine, and Pediatrics. Patient care has convinced her to be passionate about educating others on nutrition, natural childbirth, home birthing, and natural remedies for the holistic and alternative healthcare field.

Medically reviewed by:

Michael DiLeo

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