5 Best CBD For Sciatica 2021 – Does It Help Sciatica Pain?

Advertiser Disclosure

All products picked below meet our established standards. Health Canal is an ambassador for  CBD & Supplement brands, like: Gundry MD, Spruce… We will earn a small commission from your purchase. Learn more about how we earn revenue by reading our advertise disclaimer

Updated on - Written by
Medically reviewed by Kimberly Langdon, MD

cbd for sciatica

CBD or cannabidiol derived from cannabis was a turning point in the studies of the medical application of cannabis. CBD, CBN, CBG are all cannabinoids found in cannabis plants, thus called extraneous or external cannabinoids. Cannabinoids located internally in our body are known as endocannabinoids or endogenous cannabinoids.

CBD, a compound found in the leaves, stems, and stems of cannabis, can cause euphoria without intoxication and has powerful anti-analgesic properties with the most clinical benefits. All these cannabinoids interact with a network of receptors managed by the endocannabinoid system (ECS) of our body. This system is similar to any other network of organs responsible for many physical functions.Studies[1] indicate that the CBD interacts indirectly with several ECS receptors and directly with some non-ECS receptors in our body to cause a reaction from the body naturally occurs cannabinoid to suppress pain, discomfort, and inflammation.

best CBD For Sciatica on the market in (July. 2021)

CBD for sciatica – What Research Says

There is a lack of research into the effects of CBD on sciatica in both animals and humans. However, research is increasing, and recent studies have indicated that CBD should provide modest relief for people with nerve-associated pain, including sciatica.

A 2019 study[2] in Neuropsychopharmacology magazine examined the sciatic nerve injury in the mouse. Mice have been manipulated with oral THC or CBD, and CBD becomes slightly effective in reducing pain. The study, conducted by researchers at the University of Washington, used a unique technique to manage CBD in the same way that humans consume it, by voluntarily ingesting CBD-containing gums. However, given that there may be a considerable difference between the sciatic nervous model of mice and humans, detailed research will have to be done in the future for more actual results.

Another study[3] conducted a randomized controlled study on CBD oil’s effects on the lower extremities’ peripheral neuropathy. The paper, published in the current Journal of Pharmaceutical Biotechnology in 2020, noted “transdermal (topical) application of cannabidiol oil can get tremendous improvement in pain and various stressful sensations in patients with peripheral neuropathy. Treatment changed to well-tolerated by all 29 test subjects, recruited by scientists.

Based on these findings, it can be inferred that CBD can play a crucial role in helping patients with sciatica. However, several studies have shown that CBD can be a more effective analgesic and anti-inflammatory agent combined with THC.

In A Hurry? Here’s The Winner

Editor’s Choice

cbdfx tincture

CBD + CBN Oil Calming Tincture 500-4000mg

Why is it better?

  • Contains coenzyme Q10 and curcumin
  • Four different strengths available
  • Certificate of analysis available
  • Third-party tested
  • Rich in cannabinoids and terpenes

15% Off Coupon: “HEALTHCANAL”

Read Review Details

The Lineup At A Glance

Best Capsule

  • THC-free
  • Capsules are easy to swallow
  • Non-GMO, pesticide-free

Check Price

20% Off Coupon: “HEALTHCANAL”

Best Gummies

  • Whole-plant extracts
  • Lab-tested and COA available online
  • Full-spectrum

20% Off Coupon: “HEALTHCANAL”

Best Cream

  • Full-Spectrum CBD extract
  • 100% plant-based formula
  • No synthetic chemicals

10% Off Coupon: “SAVE10”

Most Variety

  • Broad-spectrum CBD or CBD isolate
  • Sourced from organic Colorado hemp grown
  • Extracted with CO2

Top 5 Best CBD Products for Sciatica 2021

CBD + CBN Oil Calming Tincture 500-4000mg

cbdfx tincture

If you are looking for an exceptional broad-spectrum CBD product with a refreshing taste, then this CBDfx oil is ideal for you. Our top choice for people with sciatica is this CBD and CBG oil tincture, which includes the two pain-relieving cannabis molecules in a 2:1 ratio.

  • Contains coenzyme Q10 and curcumin
  • Four different strengths available
  • Certificate of analysis available
  • Third-party tested
  • Rich in cannabinoids and terpenes
  • No variations of bottle size
  • Some people dislike its sweet stevia taste.

15% Off Coupon: “HEALTHCANAL”


We love this CBDfx tincture because it combines CBD with various ingredients that enhance its effects. The main element here is CBG, a cannabinoid that has been found to have beneficial pain-relieving effects. The tincture additionally contains anti-inflammatory curcumin (turmeric extract[4]) and coenzyme Q10, an effective antioxidant that improves overall health. The result is a well-rounded CBD oil that is specifically beneficial for people with pain issues.

A CBD oil tincture that contains so many exciting ingredients remains very affordable and does compromise away from quality. The hemp extract in this tincture is organic and GMO-free, CO2 extracted, and the third party tested. The tincture even comes with full certificates of analysis detailing all of the cannabinoids and terpenes it contains.

You can get this tincture in strengths from 500 to 4,000 mg per bottle. We think the low potency options are best for dealing with everyday stress or low back pain. Meanwhile, the high-efficiency option is for severe pain or inflammatory conditions.

Joy Organics Soft gels with Curcumin

Joy Organics Soft Gels With Curcumin

These Joy Organics capsules are available in specific strengths to help people struggling with different types of pain. Each soft gel is made using our water-soluble nanoemulsion technology, increasing bioavailability and, consequently, boosting effectiveness.

  • Broad-spectrum hemp extract
  • THC-free
  • Capsules are easy to swallow.
  • Non-GMO, pesticide-free
  • Soft gels are not vegetarian.
  • A little bit expensive

Check Price

20% Off Coupon: “HEALTHCANAL”


Joy Organics CBD capsules with curcumin are designed to help customers manage chronic pain and similar complaints. With a potent dose of carefully measured CBD, some of the best and fast-acting CBD capsules you can find on the marketplace today are available. Curcumin is said to have numerous health benefits along with reducing pain and inflammation. However, one of the main reasons people use curcumin supplements is to deal with different pain forms. When mixed with CBD, it results in severe pain-combat treatment that uses natural substances and has minimal side effects than opioids or other medicines.

It is available in a 10 mg version, which is very cheap and may be suitable for people with low levels of pain and discomfort. It is also available in a 25 mg version. This is much more powerful and suitable for patients with chronic pain—people who know that they will benefit from high doses of CBD. Like most reputable companies, Joy Organics uses only organic, American hemp, which is extracted using CO2 to formulate capsules, and also presents detailed third-party test reports for your convenience.

Charlotte’s Web CBD Gummies

Charlotte’s Web CBD Gummies

Charlotte Web Recovery Gummies are specially formulated with a botanical mixture of ginger, turmeric, and a unique whole-plant hemp extract known to reduce inflammation and relieve nerve pain, as well as being squeezed and delicious.

  • Whole-plant extracts
  • Lab-tested and COA available online
  • Full-spectrum
  • Different potency and strength available
  • Vegan-friendly
  • Slightly expensive
  • Limited Flavor

20% Off Coupon: “HEALTHCANAL”


These gummies are made from natural ingredients with a flavor made from real fruits and vegetables, along with wild plants like melatonin for sleep, ginger for recovery, and lemon balm, plus 5mg of full-spectrum CBD per gummy, best for those who are just starting or CBD experts trying to get more out of their current routine. When it comes to CBD for sciatic pain, these gummies can be an excellent addition to pain relief.

The recommended serving size for Charlotte’s Web Recovery Gummies is two gummies. This provides 10mg of Full Spectrum CBD, and in a nutshell, Charlotte’s Web uses every part of the plant life on the ground. Including the whole plant profile in your supplement will allow all of the compounds inside the industrial hemp plant, such as cannabinoids and terpenes, to achieve an “entourage effect” that improves the overall effectiveness of the supplement. Find out more at our Charlotte’s Web product reviews.

Elixinol Hemp Balm

elixinol balm

Elixinol offers a range of topical hemp-derived CBD products. They are made from oil hemp seeds, and most with no active CBD in them. People with sciatica will enjoy Elixinol’s Hemp Balm full Spectrum, which is available in 3 different strengths.

  • Available in three potency
  • Full-Spectrum CBD extract
  • 100% plant-based formula
  • No synthetic chemicals
  • Made With organic hemp
  • Low potency
  • Shipping takes too long

10% Off Coupon: “SAVE10”


This CBD cream for sciatica contains a full spectrum CBD extract, which includes all the different cannabinoids found in the cannabis plant. This is excellent news for people with pain conditions, as cannabinoids like THC, CBN, and CBG, can work together with CBD to prevent pain. Studies indicate that they are more potent together.

In addition to helpful cannabinoids, the balm also includes different pain-relieving botanicals, such as rosemary leaf extract, calendula flower extract, essential oils, and a type of marigold flower that has anti-inflammatory properties. Since those natural extracts are rich in terpenes, they also complement CBD results, making them more powerful and extra effective.

The great, creamy texture is made up of ingredients like grapeseed oil, andiroba oil, and sunflower oil that ensure deep hydration without making the skin greasy. The fresh scent is based on natural lemon peel oil and essential oils from Blue Mallee Eucalyptus with some specific ingredients, a soft texture, and a full spectrum of cannabinoids. We recommend this product to people with sciatic pain.

Hemp Bombs CBD Oil

Hemp Bombs CBD Oil

Hemp bombs CBD are your excellent choice if you are looking for isolate-based CBD oils or products that contain a broad spectrum of cannabinoids. Hemp Bombs only sells THC-free products designed for those who need to undergo drug testing at work and don’t have enough money to perform a false positive for THC, a common problem among customers who take high doses CBD oil every day.

  • Broad-spectrum CBD or CBD isolate
  • Sourced from organic Colorado hemp
  • Extracted with CO2
  • Third-party tested
  • Five different potencies to choose from

  • Artificial Flavoring
  • No entourage effect on some products


Just CBD oil is made from pharmaceutical-grade CBD, which means the oil is specially formulated for therapeutic purposes. Hemp Bombs CBD oil potencies range from 50mg per bottle to a maximum of 1500mg per bottle. This means that someone can choose what works for them depending on the intensity of their sciatica pain, body weight, and other dose considerations.

Hemp Bomb CBD oil is divided into three categories depending on the carrier: coconut oil, hemp seed, and liquid honey. Each of these categories has its benefits with MCT coconut oil. The more unique of these categories, however, is the one that uses liquid honey. It isn’t always traditional for CBD oil makers to sweeten it; however, honey makes the oil more palatable to people who can’t handle the natural taste. Honey also has different benefits, including anti-inflammatory properties that can prove helpful in treating sciatica.

Does CBD help with Sciatica?

Cannabinoids, with their wide variety of therapeutic and therapeutic properties, have been determined as a very beneficial remedy for sciatic nerve pain.


The most crucial part of sciatic nerve treatment is pain remedy, and CBD has been studied in depth for its ability to relieve pain. The scientists noticed trigger receptors found inside the endocannabinoid system in the CBD, which allows you to modify pain, providing an alternative to conventional painkillers.

A 2009 study[5] showed that CBD could work in synergy to make opioids more effectively reduce the desire to dose and the risk of side effects or abuse for sciatica patients who do not require pain relief.

Muscle Relaxant

Problems with sciatica often occur due to incorrect postures or long-lasting muscle strain. CBD facilitates the relaxation of muscle tissues that are stretched or strained around the compressed nerves. This can reduce pain caused by a continually squeezing nerve.


The CBD manifests itself as a CB2 receptor[6] inverse agonist, which explains its well-documented anti-inflammatory properties. There is evidence that CB2 inverse activation inhibits immune cell migration and reduces medical signs of inflammation.

In recent studies, the CBD has demonstrated promising early results as a treatment for inflammatory or neuropathic pain and a wide range of chronic pain conditions.

What Is Sciatica?

Sciatica[7] refers to damage or inflammation of the sciatic nerve, which is the largest nerve in the body. The sciatic nerve controls the muscle tissue that runs along the lower back of the knee and the lower leg. It offers sensation to the end of the thigh, sole, and lower leg. It runs from the lower back spine through the hip, knee, and ankle joint. Sciatica can affect one or both legs and usually only affects one side of the body.

Sciatica, however, is not always necessarily a problem with the sciatic nerve in and of itself. Instead, the nerve is pinched by several underlying causes, such as bone spur or herniated disc, stenosis of the spine, or possibly compression of the nerve root (pinched nerve) that can be caused by an injury.  In some sporadic cases, you will find that this condition is caused by things that don’t even affect your spines, such as pregnancy, swelling, or tumors.

Symptoms of Sciatica

These signs and symptoms of sciatica usually appear on one side only and can be one or a combination of the following:

  • Pain that runs from the lower back to the back of the leg or buttock. The pain can range from mild discomfort to sharp, burning, or stabbing pain that can become debilitating.
  • Burning, tingling, or weakness in the affected leg
  • More severe pain when sitting.
  • Sharp pain may make walking difficult.
  • Pain may get worse when sneezing or coughing.

However, in more severe cases, pain can be felt on both sides. Sciatic pain can be mild to very severe. Some people go through severe sciatica signs and symptoms to the point where they may be weakened and unable to get out of bed.

Sciatica’s symptoms can also worsen for overweight people, do not exercise regularly, wear high heels, or sleep on unsupported mattresses. Inactivity can cause sciatica signs and symptoms to get worse as it weakens muscles.

How to use CBD for sciatica?

There different methods of consuming for sciatica, and they include:

CBD oils and tinctures: For practical use, the amount of lubricant should be placed under the tongue with a dropper that comes with a bottle for about 60 seconds to allow CBD to enter your bloodstream you immediate relief. You can also use them in smoothies or contain baked goods.

CBD topicals: These are lotions, ointments, creams, serums, or patches that can be applied directly to the area. Although their effects may not last long, they are recommended for sciatic pain as they target the isolated region directly and provide specific relief.

CBD capsules: Just pop one or and you’re good to go. A pretty straightforward approach to consumption that doesn’t require the difficult task of measuring.

Risk factors & Side effects

While most customers do not experience any problems during their CBD treatment, a small percentage of customers can experience side effects. This place is still unclear, but the assumption used is age, overall health, and consumer personal genetics affect how they respond to treatment.

Some studies and reviews show that CBD is generally considered safe. Still, many people can run-in with a few side effects such as nausea, diarrhea, body weight, and appetite changes. Customers who take large doses every day can also feel irritability and fatigue.

Besides, you should control your intake from the minimum quantities and increase it according to your reaction. If you are on any other medicine, you should talk to your doctor to keep away from counter-interaction that would cause you harm. It is also essential to bear in mind that CBD can help each person differently. Important to note, you should base your use on your personal experience.

How to choose CBD products for sciatica?

There is no perfect CBD product for nerve pain. The FDA doesn’t regulate CBD as it does other medicines and supplements, so it’s essential to do your research. We choose these products based on the indicators of safety, quality, and transparency standard criteria established by our team of health experts. To make a list, CBD products had to:

  • U.S grown hemp
  • COA and third-party testing results
  • Laboratory ISO 17025-compliant
  • CBD products with less than 0.3% THC

Other factors we took into account in making these selections include:

  • Type of CBD product
  • Product potency
  • The manufacturing process and certificates
  • List of overall ingredient, including ingredients that may support pain relief
  •  Brand reputation, including:
  • Customer reviews
  • Any warning letters from the FDA
  • Any unsubstantiated health information

Final Thought

CBD holds a lot of promise if you are suffering from sciatica. It works to help reduce pain, and you have many options available for the type of CBD product you want to use. It may help manage pain every day, and since it has minimal side effects, you may try it out with concerns. Despite limited research, it seems to be beneficial. Be sure to consult your health practitioner first before starting any CBD products.If you are looking for high-quality CBD products that help relieve sciatica pain, continuously make sure you research any company that sells CBD oil out there. The market is unregulated, with a lot of inaccurately labeled products purchased online and locally.

Frequently Asked Questions

How can I get immediate relief from sciatica?

For practical use, the amount of oil should be placed under the tongue with a dropper that comes with a bottle for about 60 seconds to allow CBD to enter your bloodstream and give you immediate relief.

Which oil is best for sciatica?

Our top choice for people with sciatica is this CBD and CBG oil tincture, which includes the two pain-relieving cannabis molecules in a 2: 1 ratio.

Does CBD help with a pinched nerve?

CBD facilitates the relaxation of muscle tissues that are stretched or strained around the compressed and inflamed nerves. This can reduce sciatic pain caused by constantly pinched nerves.

Does walking help sciatica?

Walking for sciatica is a simple alternative to exercise therapy that can help rehabilitate patients who have lost physical functionality due to persistent back pain and leg pain. However, it is not always a solution to permanently cure the Sciatic nerve pain but is a step in the right direction.

+ 7 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Atalay, S., Jarocka-Karpowicz, I. and Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants, 9(1), 21. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/
  2. Abraham, A.D., Leung, E.J.Y., Wong, B.A., Rivera, Z.M.G., Kruse, L.C., Clark, J.J. and Land, B.B. (2019). Orally consumed cannabinoids provide long-lasting relief of allodynia in a mouse model of chronic neuropathic pain. Neuropsychopharmacology, 45(7), 1105–1114. Available from: https://www.nature.com/articles/s41386-019-0585-3 
  3. Xu, D.H., Cullen, B.D., Tang, M. and Fang, Y. (2020). The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities. Current Pharmaceutical Biotechnology, 21(5), 390–402. Available from: https://pubmed.ncbi.nlm.nih.gov/31793418/ 
  4. Sahdeo Prasad and Aggarwal, B.B. (2011). Turmeric, the Golden Spice. Nih.gov. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92752/ 
  5. Elikkottil, J., Gupta, P. and Gupta, K. (2009). The analgesic potential of cannabinoids. Journal of opioid management, 5(6), 341–57. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728280/ 
  6. Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. (2018). International Journal of Molecular Sciences, 19(3), 833. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877694/ 
  7. Davis, D., Kushagra Maini and Arvind Vasudevan (2020). Sciatica. Nih.gov. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507908/

Written by:

Healthcanal Staff

Medically reviewed by:

HealthCanal Editorial team is a team of high standard writers, who qualified the strict entrance test of Health Canal. The team involves in both topic researching and writting, which are under supervision and controlled by medical doctors of medical team.

PubMed Central

Database From National Institute Of Health

U.S National Library of Medicine
Go to source