09:11pm Thursday 14 November 2019

Blood vessel protein discovery needs further investigation

Lab scientist

Researchers from Queen Mary, University of London and the University of Surrey showed the protein pregnane X receptor can switch on different protective pathways to deal with a variety of drugs, foreign chemicals and food products in the blood.

The study authors say PXR is known to sort out waste products in the liver but believe it could also protect someone’s blood vessels and possibly prevent heart disease and stroke.


Unexpectedly, a protective protein found in the liver is also present in blood vessels

Our Associate Medical Director, Professor Jeremy Pearson, said: “This research has found, unexpectedly, that a protective protein found in the liver is also present in blood vessels. It may be important in helping to stop the development of cardiovascular disease.

“We now need further studies to test this discovery and determine whether it could one day help prevent heart and circulatory disease – the UK’s biggest killer.”

The research was co-authored by Professor David Bishop-Bailey at Queen Mary, University of London. It was published in the Cardiovascular Research journal.

British Heart Foundation is a registered Charity No. 225971. Registered as a Company limited by guarantee in England & Wales No. 699547.

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