05:43am Wednesday 18 October 2017

McMaster study finds more gut reaction to arthritis drugs

A team from the Farncombe Family Digestive Health Research Institute has found those stomach acid-reducing drugs, known as proton pump inhibitors, may actually be aggravating damage in the small intestine caused by the nonsteroidal anti-inflammatory drugs, also known as NSAIDs.

In a study published in the medical journal Gastroenterology, principal investigator John Wallace says the extent of the hard-to-detect damage caused to the small intestine has only recently been discovered through use of small video cameras swallowed like pills.

“Suppressing acid secretion is effective for protecting the stomach from damage caused by NSAIDs, but these drugs appear to be shifting the damage from the stomach to the small intestine, where the ulcers may be more dangerous and more difficult to treat,” said Wallace. He is director of the Farncombe institute and professor of medicine of the Michael G. DeGroote School of Medicine at McMaster.

He added that the use of probiotics is being investigated as a potential cure for the small intestine damage.

The study was funded by the Canadian Institutes of Health Research (CIHR) and a CIHR/Canadian Association of Gastroenterology Fellowship.

 

-30-

 

For more information, please contact:

 

Veronica McGuire

Media Relations Coordinator

Faculty of Health Sciences

McMaster University

905-525-9140, ext. 22169

vmcguir@mcmaster.ca


Share on:
or:

MORE FROM Bones and Muscles

Health news