The research, published in the medical journal Arthritis Care & Research, aimed to investigate which patient-reported activities are first associated with knee pain, in order to improve early detection of osteoarthritis and so increase the chances of people seeking effective treatment.
Philip Conaghan, Professor of Musculoskeletal Medicine in the School of Medicine, led the study. He said: “At present we have little concept of ‘early’ osteoarthritis and often only see people when they have significant longstanding pain and loss of function. This research is vital to understanding early symptoms of knee osteoarthritis.
“Knowing this will help us intervene earlier, perhaps leading to more effective ways of treating this very painful condition.”
For this study, the team looked at the cases of 4,673 people who have, or are at high risk of, osteoarthritis. Participants completed annual surveys for up to seven years in order to help the researchers track the emergence of pain during different activities over a long-term period.
The study revealed that using stairs was the first weight-bearing task in which people noticed pain.
This was followed by pain emerging during walking, standing, lying or sitting and then finally when resting in bed.
The study was funded by the National Institute of Health Research, Arthritis Research UK, the Wellcome Trust and the Engineering and Physical Sciences Research Council.
The paper, “Toward a Clinical Definition of Early Osteoarthritis: Onset of Patient-Reported Knee Pain Begins on Stairs. Data from the Osteoarthritis Initiative”, by Hensor et al, is available from the Press Office.
Professor Philip Conaghan is available for interview. Contact the University of Leeds press office on 0113 343 4031, out-of-hours-mobile on 07712 389448 or email firstname.lastname@example.org