07:55pm Tuesday 23 July 2019

Research in the News: Yale scientists track origins of multiple sclerosis

Yale researchers, however, have uncovered evidence that this damaging response may begin in the lymph nodes. 

The finding, reported in the issue of journal Science Translational Medicine, tracks the origin of the autoimmune response in the lymph nodes and later its arrival in the brain, where it contributes to tissue damage that results in numbness, loss of vision, and debilitating fatigue.

“This helps explain why treatments that work outside the central nervous system can ease MS symptoms and may give us clues how to develop even more effective treatments,” said neuroimmunologist Kevin O’Connor, one of the senior authors of the paper. 

For more information, see the study at http://stm.sciencemag.org/content/6/248/248ra107.

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Bill Hathaway

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