Atherosclerosis in artery. Photo: Science Photo
Atherosclerosis, or hardening of the arteries, is an inflammatory disease affecting the arteries supplying the brain, heart, other organs and extremities with oxygen-rich blood. A well-established atherosclerosis disease, with accumulation of plaque narrowing the arteries, can obstruct the blood supply to the brain and other vital organs. Atherosclerosis in the neck arteries can cause stroke. The serious condition, known as carotid stenosis, is quite common in the elderly as well as in people with risk factors such as hypertension, smoking, diabetes, hypercholesterolemia and obesity.
Atherosclerosis disease progression can be controlled by medical treatment including cholesterol-lowering drugs, and significant narrowing in symptomatic patients can be treated surgically.
“We know that preventive surgical treatment of carotid stenosis is only beneficial for a small subgroup, and that most asymptomatic patients will do better with only medical therapy. By using ultrasound, we can identify the patients who are at a higher risk of stroke and thus would benefit from surgery. But preventing unnecessary surgical intervention in most cases is equally important,” says Fisnik Jashari, doctoral student at the Department of Public Health and Clinical Medicine and author of the dissertation.
To assess the nature of atherosclerosis disease and the extent of plaque build-up, the non-invasive ultrasound method remains favoured over most others because it is radiation free, cheap and patient-friendly.
Fisnik Jashari comes from Prishtina in Kosovo, where he works as resident doctor in Neurology. He is a doctoral student in the Department of Public Health and Clinical Medicine at Umeå University.
For more information, please contact:
Fisnik Jashari, Department of Public Health and Clinical Medicine, Umeå University
Phone: +46 90 785 00 00, +37 744 19 47 92
About the public defence of the dissertation:
On Thursday 26 November, Fisnik Jashari, Department of Public Health and Clinical Medicine, defends his dissertation entitled: Carotid artery disease: plaque features and vulnerability. Opponent: Christine Kremer, Department of Clinical Sciences at Lund University. Main supervisor: Michael Henein, professor at the Department of Public Health and Clinical Medicine.
The public defence of the dissertation will take place at 09:00 at the University Hospital of Umeå (NUS), Unod T9, Room D.
Editor: Anna Lawrence