12:17am Thursday 19 October 2017

Poorer patients with lung cancer less likely to receive treatment than wealtheir patients

This inequality in treatment may contribute to the higher death rates for lung cancer in poorer patients.

In a paper published today in the journal PLoS Medicine the authors found that this disparity could not be explained by differences in national healthcare systems or the stage at which cancer is diagnosed.

The team from Newcastle University and Fuse, the Centre for Translational Research in Public Health, analysed data from 46 previous studies from the UK and the US and also from Canada, Sweden, Australia, Italy, France, and New Zealand.

In their analysis, the authors found that patients with lung cancer who were from the lowest socioeconomic groups were 21 % less likely to receive any treatment than patients from the highest socioeconomic groups. Lower socioeconomic position was also linked with a lower chance of receiving surgery (32% less likely) and chemotherapy (18% less likely), but not radiotherapy.

These findings are important as, in the UK and USA, lung cancer is the most common cause of cancer death and treatment with surgery, chemotherapy or radiotherapy improves survival rates in patients with lung cancer. A previous study in England and Wales has found that 1,300 lung cancer deaths could be avoided if survival rates were the same as the highest socio-economic groups.

The authors also found that this link between socioeconomic position and receiving treatment was similar in studies from countries where healthcare is free for everyone (for example, in the UK) and in countries that have private insurance healthcare systems (for example, in the US). It is unclear at the moment what is driving these inequalities in receipt of treatment.

Lynne Forrest, lead author on the paper, said: “We were surprised that these inequalities remained even after we took account of the differences in healthcare system and in how advanced the cancer was at diagnosis.

“We do not know why this is happening, but we think it could be due to three possible factors. 

“Firstly co morbidity; poorer people may have other things wrong with them, making them unable to undergo aggressive cancer treatment.

“Secondly patient choice; poorer people may weigh up the benefits of treatment differently and therefore turn down the opportunity for treatment that could extend their life for a short while. There may be socioeconomic barriers to treatment uptake, such as access to transport, family circumstances, work flexibility and social support, that influence whether patients choose to undergo treatment.

“Thirdly, it may be that doctors are not communicating effectively with poorer or less well-educated patients. All of these factors will need to be looked at, as well as any others that we may uncover in future research.”

Professor Martin White, Director of Fuse and study co-author added: “This is a serious public health concern that needs to be addressed. We are discovering that a range of health conditions are subject to inequalities in the way that healthcare is accessed and delivered. These can lead to unequal outcomes which may compound the already unequal distribution of diseases in the population.”

Reference: http://www.plosmedicine.org/article/info:doi%2F10.1371%2Fjournal.pmed.1001376

Key Facts:

  • Newcastle University is a Russell Group University
  • We rank in the top 20 of UK universities in The Sunday Times 2013 University Guide
  • Amongst our peers Newcastle is:
    • 10th in the UK for student satisfaction
    • In the UK’s top 12 for research power in Science and Engineering
  • 93% of our students are in a job or further training within six months of graduating (HEFCE 2012)
  • We have a world-class reputation for research excellence and are spearheading three major societal challenges that have a significant impact on global society. These themes are: Ageing and Health, Sustainability, and Social Renewal
  • Newcastle University is the first UK university to establish a fully owned international branch campus for medicine at its NUMed Campus in Malaysia which opened in 2011
  • Our International students put Newcastle University in world’s top 12 (ISB 2011)

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