Alcohol is responsible for more than one-in-twenty deaths of New Zealanders aged under 80, new University of Otago research suggests. Although most harm to young people’s health from drinking is through injury, alcohol also contributes to chronic diseases, and breast cancer is the leading cause of death from alcohol in both Māori and non-Māori women overall.
Cells from basal cancers are able to switch relatively easily into cancer stem cell (CSC) state, unlike luminal breast cancer cells, which tend to remain in the non-CSC state. The gene ZEB1 is critical for this conversion. The difference in ZEB1’s effects is due to the way the gene is marked in the two types of cancers.