By Gwen Ericson — When bees sting, they pump poison into their victims. Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at Washington University School of Medicine in St. Louis. The researchers attached the major component of bee venom to nano-sized spheres that they call nanobees.
PHILADELPHIA – “A biologist, a physicist, and a nanotechnologist walk into a …” sounds like the start of a joke. Instead, it was the start of a collaboration that has helped to decipher a critical, but so far largely unstudied, phase of how cells divide. Errors in cell division can cause mutations that lead to cancer, and this study could shed light on the role of chromosome abnormalities in uncontrolled cell replication.
By Gwen Ericson — Tumor growth can start from stem cells in the gut, say researchers studying fruit flies at Washington University School of Medicine in St. Louis. They found that tumors can grow from adult stem cells that have lost a specific tumor-suppressor gene. The gene, Apc, has previously been implicated in human gastrointestinal cancers, including colon cancer.
By Gwen Ericson — When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have uncovered new information on the notion that sugar "feeds" tumors. The findings may also have implications for other diseases such as diabetes. The research is published in the journal Proceedings of the National Academy of Sciences (PNAS).
Patients who receive additional information about lymphedema report significantly fewer symptoms and practiced more risk-reducing behaviors, according to a recent study co-authored by Deborah Axelrod, MD, associate professor in the department of surgery at NYU Langone Medical Center and a member of the NYU Cancer Institute. Risk-reducing behaviors include elevating the affected limb to promote fluid drainage, avoiding blood draws and injections to the affected limb and avoiding tight-fitting clothing, which can aggravate symptoms.
Tiny, solitary spikes that stick out of nearly every cell in the body play a central role in a type of skin cancer, new research has found. The discovery in mice shows that the microscopic structures known as primary cilia can either suppress or promote this skin cancer, depending on the mutation triggering the disease.