Sun exposure may increase survivors’ risk for a second diagnosis of melanoma
PHILADELPHIA — Survivors of melanoma were more likely to limit exposure to the sun than people who had never had the disease, but some still reported seeking out suntans and getting sunburns, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Incidence of melanoma, the deadliest form of skin cancer, has risen steadily for the past 30 years. Melanoma is now the sixth most common cancer in the United States, with an estimated 76,380 cases diagnosed in 2016, according to the National Cancer Institute’s Surveillance, Epidemiology, and End Results Program. Ultraviolet radiation from the sun has been proven to cause melanoma.
“At a time when rates of many cancer types are declining, the rising incidence of melanoma is worrisome,” said the study’s lead author, Rachel Isaksson Vogel, PhD, an assistant professor in the Department of Obstetrics, Gynecology and Women’s Health at the University of Minnesota. “People who have survived melanoma are at high risk of another diagnosis, so reducing exposure to the sun is really crucial.”
In this study, Vogel and colleagues compared sun exposure and protection behaviors in long-term melanoma survivors with those who had never had the disease, asking participants about the amount of time they had spent outdoors in the summer, and about sun protection methods such as wearing sunscreen, staying in the shade, wearing hats, and intentionally tanning. Participants were also asked to report the number of red or painful sunburns they had experienced in the past year, and whether they had used a tanning bed or booth in the past year.
The study comprised 724 melanoma survivors and 660 controls. All were between the ages of 25 and 59, and the survivors had been diagnosed with invasive cutaneous melanoma between July 2004 and December 2007.
Overall, Vogel said, the survivors were more likely to report optimal sun protection behaviors than those in the control group. Some highlights:
• 34.3 percent of survivors spent more than an hour outside on summer weekdays, compared with 44.4 percent of controls;
• 19.5 percent of survivors said they had gotten a sunburn in the previous year, compared with 36.5 percent of controls;
• 1.7 percent of survivors said they had used a tanning booth or bed in the previous year, compared with 6.8 percent of controls; and
• 61.9 percent of survivors often or always wore sunscreen, compared with 38.4 percent of controls.
However, the study revealed suboptimal behaviors in some melanoma survivors. Nearly 20 percent said they had gotten sunburned in the previous year, and on weekend days, sun exposure was roughly equal between the two groups, with 74.8 percent of the survivors and 79.7 percent of the controls spending more than two hours outside.
Vogel said that in conversations with individuals diagnosed with melanoma, many survivors expressed a desire to “just live their lives,” playing with their children, exercising, and socializing outdoors. She said that in most cases, the participants had been diagnosed with stage 1 disease, when melanoma is often easily treated and has a five-year survival rate of 98 percent.
“Because an early-stage melanoma diagnosis and treatment was likely a fairly minor experience for most survivors, they might not understand how serious an illness this is,” Vogel said. “Survivors of melanoma have a nearly nine-fold risk of developing melanoma again, and they can reduce that risk if they make sun protection a priority.”
Vogel noted that one limitation of the study is that data on second primary melanomas—a new diagnosis at a different site than the initial diagnosis— were not available for all participants. Also, she said, it is possible that some subjects over-reported their sun protection behaviors.
This study was funded by a grant from the Masonic Cancer Center of the University of Minnesota’s Internal Grants Program, as well as a grant from the National Cancer Institute. Vogel declares no conflicts of interest.
American Association for Cancer Research