Most patients suffering liver toxicity due to medications or herbal or dietary supplements recover from the acute liver injury without long-term problems, but some do not survive the injury or they require liver transplantation. In a recent study, nearly 10% of patients with definite, highly likely, or probable drug-induced liver injury had a fatal outcome within 2 years of onset.
In the 107 deaths among 1089 patients in the study, drug-induced liver injury was the primary cause of death in 68 patients and was a contributing cause in another 15 (at total of 7.6%). The remaining 22 patients had fatal outcomes unrelated to drug-induced liver injury.
The findings are published in Hepatology.
Link to Study: http://onlinelibrary.wiley.com/doi/10.1002/hep.29283/full
The premier publication in the field of liver disease, HEPATOLOGY publishes original, peer-reviewed articles concerning all aspects of liver structure, function and disease. Each month, the distinguished Editorial Board monitors and selects only the best articles on subjects such as immunology, chronic hepatitis, viral hepatitis, cirrhosis, genetic and metabolic liver diseases and their complications, liver cancer, and drug metabolism.