Study suggests quality of life worsens with Geographic Atrophy of the Macula

Fort Lauderdale, Fla. — A longitudinal study funded by the National Institutes of Health (NIH) suggests the ability to read, recognize faces or find a street sign will deteriorate significantly over time for adults with age-related geographic atrophy of the macula (GA). Results of the research will be presented this week at the 2011 Annual Meeting of the Association for Research in Vision and Ophthalmology.

In this study, a questionnaire was completed at baseline and annually by subjects enrolled in the NIH-funded prospective natural history study of geographic atrophy from AMD from 1992-2000. At each visit, subjects were measured for best-corrected visual acuity, contrast sensitivity, reading rate, low luminance visual acuity and microperimetry. The GA area was measured using color fundus photographs.

The reports showed that subjects ‘difficulty in reading, haziness, face recognition and finding signs worsened with worse visual acuity and with larger GA area at baseline. Longitudinally, reading and face recognition deteriorated significantly.

According to the researchers, “This information will be helpful in designing quality of life questionnaires for future GA clinical trials.

Abstract Title: Quality Of Life Measures In Age-related Geographic Atrophy Of The Macula
Presentation Start/End Time: Sunday May 1, 2011; 8:30 – 10:15am
Location: Hall B/C
Session Number: 105

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