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Best CBD Gummies & Hemp Edibles 2022: Top 10 Brand Reviews

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

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cbdfx gummies

CBDfx

  • Made with all organic ingredients
  • Variety of gummies for different needs
  • Third-party tested with COA

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Spruce CBD Gummies

Spruce CBD gummies

  • Full-spectrum CBD derived from unique heirloom hemp
  • Low calorie and low sugar
  • Third party tested and made with some organic ingredients

Free Shipping and 15% Off Coupon: HEALTHCANAL

cbdistillery gummies

CBDistillery

  • Offers gummies with full-spectrum, broad-spectrum, and isolate CBD
  • Products are U.S. Hemp Authority certified and third-party tested
  • 60-day return policy on purchases

15% Off Coupon: HEALTHCANAL

Cannabidiol (CBD) is an increasingly popular substance that people use for myriad reasons, from stress relief to managing pain.

If you want to experience the health benefits of CBD without taking a CBD tincture or vaping, CBD gummies offer an easy and alternative way to benefit from CBD. They are often easy to eat, taste better than tinctures, and you don’t have to worry about harsh smoke irritating[1] your throat or lungs.

With new companies offering gummies popping up in the CBD industry, it is hard to find the best CBD gummy for you.

We’ve rounded up some of the best CBD gummies of 2022.

Best CBD Gummies for Pain, Sleep & Anxiety (September. 2022)

Effects Of CBD Gummies

The available research on the health benefits of CBD is still limited, but CBD has the potential to be effective for a number of benefits.

CBD can be effective for our health because CBD and other cannabinoids can connect to receptors in our endocannabinoid system. The endocannabinoid system in our brain and the central nervous system helps our bodies maintain homeostasis[2] or balance.

Studies find that CBD may be effective in supporting mood[3], reducing symptoms related to some chronic mental health conditions, and reducing anxiety. Other studies find that CBD can reduce inflammation[4] even without THC present. Along with reducing inflammation, CBD may be useful for pain management[5] associated with inflammatory conditions. CBD may even help reduce blood pressure[6] during times of stress and improve the flexibility of blood vessels.

The Line Up At A Glance

cbdfx gummies

Best for Wellness

CBDfx

  • Made with all organic ingredients
  • Variety of gummies for different needs
  • Third-party tested with COA

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Spruce CBD Gummies

Editor’s choice

Spruce CBD gummies

  • Full-spectrum CBD derived from unique heirloom hemp
  • Low calorie and low sugar
  • Third party tested and made with some organic ingredients

Free Shipping and 15% Off Coupon: HEALTHCANAL

cbdistillery gummies

Best Value Brand

CBDistillery

  • Offers gummies with full-spectrum, broad-spectrum, and isolate CBD
  • Products are U.S. Hemp Authority certified and third-party tested
  • 60-day return policy on purchases

15% Off Coupon: HEALTHCANAL

PlusCBD

Best for Sleep

PlusCBD

  • Contains third-party tested full-spectrum CBD
  • Made with organic ingredients
  • Variety of products

20% Off Coupon: HEALTHCANAL

royal CBD Gummies

Best Organic

Royal CBD

  • Made with 100% organic ingredients
  • Highly rated by customers for tasting good
  • Available in broad-spectrum and full-spectrum varieties

20% Off Coupon: HC20

Charlotte’s Web CBD

Best Full-Spectrum

Charlotte’s Web

  • Sourced from unique hemp strain
  • Affordable CBD gummies
  • Neutraceutical blends are made with well-studied botanical ingredients

15% Off Coupon: HEALTHCANAL

Joy-Organics-CBD-Gummies-1

Best Broad-Spectrum

Joy Organics

  • Made with organic ingredients and cruelty-free
  • Made with THC-free, organic broad-spectrum CBD
  • COA has extensive details of testing

Check Price

20% Off Coupon: HEALTHCANAL

five cbd

Best CBD Rosin

Five CBD

  • CBD rosin extraction process
  • Full-spectrum CBD gummy
  • COA available for all products

20% Off Coupon: HEALTHCANAL

Green Roads

Best CBD Isolate

Green Roads

  • Full-spectrum and CBD isolates Can purchase a sample pack for low price
  • Formulated by pharmacists

15% Off Coupon: HEALTHCANAL

sunday scaries gummies

Best Stress Relief

Sunday Scaries

  • COAs for raw products and finished products
  • Has added vitamins and botanicals Unique in offering multiple flavors

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Top 10 Best CBD Gummies For Sleep & Anxiety 2022

CBDfx

cbdfx gummies

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See CBDfx Reviews

CBDfx has CBD gummies to support all areas of health – from a general multivitamin to antioxidant and detox support, and even sleep support.

  • Made with all organic ingredients
  • Variety of gummies for different needs
  • Each batch of gummies are third-party tested with a COA
  • Gummies are higher in calories compared to others

CBDfx is a CBD company launched by Ali Esmaili and Jameson Rodgers in 2014 in California’s San Fernando Valley.

CBDfx’s products are made with all-organic ingredients, are free of artificial sweeteners, and are free of genetically modified organism (GMO) products. Each batch of CBDfx’s gummies is third-party tested, with lab results easily available on their website.

CBDfx has a wide variety of high-quality CBD products, including a detox gummy with apple cider vinegar, a sleep gummy containing melatonin, a gummy multivitamin, and a superfood gummy featuring turmeric and spirulina. This way, customers can get a little something extra from their CBD gummy.

The original CBD gummy bears (mixed berry flavor) from CBDfx have 25 mg of broad-spectrum CBD per gummy (or 50 mg per full serving), making dosing CBD gummies easy.

Every bottle of CBDfx high-quality CBD gummies costs $54.99 each and contains 60 gummies (or 30 servings).

If you’re not satisfied with your product for any reason, CBDfx offers a 60-day moneyback guarantee.

Spruce CBD

Free Shipping and 15% Off Coupon: HEALTHCANAL

See Spruce CBD Reviews

Spruce CBD uses an heirloom hemp strain to provide a unique terpene profile to their CBD products. Spruce CBD makes potent CBD gummies with the best ingredient quality.

  • Full-spectrum CBD derived from unique heirloom hemp
  • Low calorie and low sugar
  • Third-party tested and made with some organic ingredients
  • It may taste more bitter than other CBD gummies
  • Expensive

Spruce CBD is a family-owned CBD company that was launched in 2018 by Tony Spencer, who wanted to create a CBD company that was consistent in quality, customer service, and efficacy.

Spruce CBD uses an heirloom strain of hemp that came to the U.S. during the War of 1812, which lends it a unique terpene profile. All of Spruce CBD’s products are third-party tested, free of pesticides, and have Certificate of Analysis (COA) lab results easily available on their page.

Spruce CBD gummies contain 25 mg of full-spectrum CBD oil each and do not contain any artificial sweeteners or flavors. While these gummies may taste more bitter than others, they are lower in calories and sugar and have a higher potency than some other CBD gummies on the market.

A container of Spruce CBD gummies contains 30 chews and costs $89 per container. A subscription can save you 15% on your purchase, and you get free shipping.

All products have a 30-day refund policy.

CBDistillery

cbdistillery gummies

15% Off Coupon: HEALTHCANAL

See CBDistillery Reviews

CBDistillery has a range of CBD gummies that are high-quality, contain higher doses of CBD per serving than some other brands, and still manage to be an affordable and reliable choice.

  • Offers gummies with full-spectrum, broad-spectrum, and isolated CBD
  • Products are U.S. Hemp Authority certified and third-party tested
  • 60-day return policy on purchases
  • Customers report delays with product refunds

Founded in 2016, CBDistillery is a premier source for high-quality, fairly priced hemp-derived CBD products and education. Their products are U.S. Hemp Authority certified, third-party tested for potency and purity, and non-GMO, and their hemp is grown using natural farming practices.

CBDistillery CBD gummies are available in full-spectrum, broad-spectrum, and CBD to isolate gummies. This is great to meet the needs of any CBD user who may or may not want certain hemp-derived compounds in their gummy. Their full-spectrum CBD gummies guarantee you get the optimum entourage experience.

The full-spectrum and broad-spectrum CBD gummies have 30 mg of CBD per serving, while the Isolate CBD gummies have 25 mg of CBD. CBDistillery also offers some gummies that combine CBD with botanicals and other cannabinoids to meet specific daytime or nighttime needs.

CBDistillery’s CBD gummies cost between $50-60 per 30-count bottle. The Gummies Mix Pack combining the Anytime gummies and Sleep gummies costs only $100.

Save 20% on your order when you subscribe. All products have a 60-day money-back guarantee.

PlusCBD

PlusCBD

20% Off Coupon: HEALTHCANAL

See Plus CBD Reviews

PlusCBD has full-spectrum gummies packed with well-studied botanicals to support a night of restful sleep and a calm mood throughout the day.

  • Contains third-party tested full-spectrum CBD
  • Made with organic ingredients
  • Has a variety of products for individual needs
  • Consumers complain about strong odor and flavor

PlusCBD is a brand from CV Sciences, a health company with a mission to improve the quality of life through nature and science.

PlusCBD CBD gummies are vegan-friendly and made with full-spectrum CBD oil, gluten-free, and free of artificial flavors or artificial sweeteners. All of their products on the CBD market are third-party tested and have COAs available. Sweetening is added with organic cane sugar and organic tapioca syrup.

If you’re new to CBD or need a low dose, PlusCBD’s CBD-infused gummies come in 10 mg of full-spectrum oil in either citrus punch or cherry mango flavor.

For those looking for support with feeling calm or sleeping, PlusCBD has products for that as well.

The Sleep CBD gummies include 10 mg of full-spectrum CBD, melatonin, lemon balm extract, and magnolia bark extract to support sleep. PlusCBD’s Calm gummies have 10 mg full-spectrum CBD, L-theanine, and 5-HTP from Griffonia simplicifolia seed extract. 

You can purchase PlusCBD gummies in a 30-count or 60-count container. The 30-count container costs $27.99, while a 60-count container of PlusCBD CBD gummies costs $44.99.

The Calm and Sleep CBD gummies cost $29.99 and come in 30-count containers.

Subscriptions to PlusCBD products can save you 20% on your purchase. All products have a 30-day refund policy.

 Royal CBD

royal CBD Gummies

20% Off Coupon: HC20

See Royal CBD Reviews

RoyalCBD is a premium CBD brand that has a small selection of high-quality CBD gummies. Their gummies are 100% organic and consistent in their potency and quality.

  • Made with 100% organic ingredients
  • Highly rated by customers for tasting well
  • Available in broad-spectrum and full-spectrum varieties
  • Third-party tested with available COAs
  • Does not offer specialized blends for sleep or other purposes

Royal CBD is a highly-trusted CBD brand that was established by CBD oil advocates in 2018.

Royal CBD’s gummies contain CBD derived from sustainably grown organic hemp plants using a supercritical CO2 extraction. All of their products are made with 100% organic ingredients, non-GMO, vegan-friendly, and third-party tested for quality and potency (with available COAs).

Royal CBD offers two types of organic CBD gummies – a 25 mg broad-spectrum CBD gummy and a 25 mg full-spectrum CBD. These gummies work well for any lifestyle as they are low in sugar and calories. Each bottle of Royal CBD gummies comes in an assortment of flavors (strawberry, orange, and grape), and customers consistently rate them as being delicious. Customers also say in reviews that these gummies are consistent in their potency.

A 30-count container of broad-spectrum or full-spectrum CBD gummies costs $67 per bottle.

Save more when you buy a 2-pack or 4-pack of Royal CBD’s gummies. 

Save an additional 15% when you get your gummies delivered monthly. All products have a 30-day return policy.

Charlotte’s Web

Charlotte’s Web CBD

15% Off Coupon: HEALTHCANAL

See Charlotte’s Web Reviews

Charlotte’s Web has a line of CBD gummies using full-spectrum hemp-derived CBD from a special hemp strain. Its nutraceutical line contains botanicals known to be effective for their health benefits.

  • CBD is sourced from a unique hemp strain
  • Affordable CBD gummies
  • Nutraceutical blends are made with well-studied botanical ingredients
  • Must take two gummies per serving due to low CBD dosage

Charlotte’s Web is one of the first CBD companies founded back in 2012 by the Stanley Brothers from Colorado. 

Charlotte Web’s gummies are made with full-spectrum hemp extract made from the proprietary Charlotte’s Web hemp strain. They have organic ingredients and have COAs available from their extensive third-party testing. 

The Daily Wellness gummies contain 15 or 25 mg of CBD per serving and are meant for daily use.

The Immunity gummies have 10 mg CBD along with astragalus, vitamin C, and D3 to support a strong immune system.

Charlotte Web’s Calm gummies combine 10 mg of CBD with lemon balm to support relaxation.

The Sleep CBD gummies have 10 mg of CBD and melatonin to support sleep quality.

The Recovery CBD gummies have 10 mg of CBD, ginger, and turmeric to support exercise recovery by helping healthy joints and healing from exercise-induced inflammation.

There is also a THC-free CBD gummy, which differs from CBD isolate by preserving additional cannabinoids and terpenes. These gummies come in 15 mg and 25 mg doses per serving.

Most of Charlotte Web’s CBD gummy bears are available in 30-count, 60-count, and 90-count containers, costing between $23.99-$55.99 per container. All products have a 30-day customer satisfaction guarantee.

Joy Organics

Joy Organics

Check Price

20% Off Coupon: HEALTHCANAL

See Joy Organics Reviews

Joy Organics sells premium CBD gummies made with organic ingredients and developed with high standards. Joy Organics CBD gummies are unique in being extracted only from hemp plant buds and employing only pure CBD.

  • Made with organic ingredients and cruelty-free
  • Made with THC-free, organic broad-spectrum CBD
  • COA has extensive details of testing
  • Only one CBD gummy product is available

Joy Organics is a premium organic CBD brand founded by Joy and Tom Smith. Joy Organics focuses on developing premium CBD products from organic hemp and providing great customer service. This company is a member of the U.S. Hemp Roundtable, a coalition committed to safe hemp and CBD products.

Joy Organics CBD gummies contain just 10 mg of organic broad-spectrum CBD oil per serving and are 0.0% THC-free gummies. Their CBD is extracted only from the buds of the hemp plant.

This is another brand that is great for people new to taking CBD gummies. These vegan gummies are sweetened with organic cane sugar and organic tapioca syrup.

These CBD gummies are also made with organic ingredients, lab-tested, cruelty-free, and are even transported using carbon-neutral shipping.

You can choose to purchase gummies in both green apple and strawberry lemonade flavors. Each gummy is only ten calories and has 3 grams of added sugars.

A 30-count container of Joy Organic’s CBD gummies is $39.95.

When subscribing, save 25% in February and 20% on your purchase in subsequent months. You can choose to renew your subscription every 2, 4, 6, 8, or 12 weeks.

All Joy Organics products have a 90-day money-back guarantee.

Five CBD

five cbd

20% Off Coupon: HEALTHCANAL

See Five CBD Reviews

Five CBD uses a unique CBD extraction process to make truly full-spectrum CBD products. If you’re interested in trying something new in CBD products, Five CBD may be for you.

  • Unique CBD rosin extraction process
  • Full-spectrum CBD gummy
  • COA available for all products
  • Limited transparency about brand
  • Unable to see Supplement Facts label

Five CBD is a company founded by John Larsen in Laguna Beach, CA. It is a relatively new CBD company. Unfortunately, their website does not disclose much information about the brand’s origin story and values.

Five CBD gummies are unique in that their CBD is CBD rosin. CBD rosin is produced differently from butane or CO2 extracted CBD. CBD rosin is produced by careful heat and pressure and does not contain any solvents or solvent byproducts.

CBD rosin is full-spectrum, containing CBD, THC, CBG, CBN, terpenes, and flavonoids.

Five CBD rosin gummies have 15 mg of CBD rosin per gummy. The Daytime gummies come in a candied lemon flavor, and the Nighttime gummies are a citrus flavor.

The website has some issues, and while you can see the COA of the gummies, the Supplement Facts label does not load. This severely limits the transparency that customers should have before purchasing.

A 20-count container of Five CBD’s CBD rosin gummies costs $39.99. You can also purchase a 40-count for $54.59 or a 60-count container for $99.99.

Subscribe to Five CBD products to save 30% on your delivery. All products have a 30-day money-back guarantee.

Green Roads

Green Roads

15% Off Coupon: HEALTHCANAL

See Green Roads Reviews

Green Roads is a trusted brand because it is pharmacist-formulated and focused on consumer advocacy. Their Relax Bears made with CBD isolate are a great option for people wanting a high-quality pure CBD isolate.

  • The brand has full-spectrum and CBD isolate gummies
  • Can purchase a sample pack for a low price
  • Formulated by pharmacists
  • CBD isolate is not vegan-friendly
  • 30-day return policy only for unopened products

Green Roads is a pharmacist-formulated brand co-founded by Laura Fuentes, who was a licensed compounding pharmacist for over two decades. As a result, Green Roads is driven by consumer advocacy, pushing for greater transparency and stricter CBD requirements.

All of Green Roads’ products are third-party tested and have COAs available for every product batch.

Green Roads’ CBD Relax Bears are available in 10 mg, and 25 mg CBD isolate gummies. Each jar comes in an assortment of flavors, including blue raspberry, lemon, cherry, green apple, and orange.

The Rise N’ Shines Immune Support gummies contain 25 mg of full-spectrum CBD per gummy and has vitamin B12, vitamin C, and elderberry to start your day.

The Sleepy Zs CBD gummies have 25 mg broad-spectrum CBD per gummy and melatonin to help you sleep.

A 30-count container of the 10 mg Relax Bears is $37.99, while a 30-count container of all 25 mg gummies is $49.99. You can also purchase small sample packets containing 50 mg CBD worth of CBD gummies for only $6.49.

Save 20% on your purchase when you subscribe. Only new and unopened products come with a 30-day money-back guarantee.

Sunday Scaries

sunday scaries gummies

20% Off Coupon: HEALTHCANAL

See Sunday Scaries Reviews

Sunday Scaries makes products for people who dread Mondays or just want to manage their daily stress. Their CBD gummies have added nutrients to help balance your mood.

  • COAs for raw products and finished products
  • Has added vitamins and botanicals to promote calmness
  • Unique in offering multiple flavors including holiday flavors
  • Only comes in 20-count containers

Sunday Scaries makes CBD products to help you better deal with managing stress and negative thoughts for a “scare-free” life.

All Sunday Scaries products go through a 3-step quality assurance system – CBD derived from USDA-certified hemp grown in the U.S., raw-product COAs, and finished-product COAs.

The original Sunday Scaries formula contains 10 mg of broad-spectrum CBD per gummy and vitamin B12 and D3 to help balance your mood.

The Vegan AF sour gummies are vegan CBD gummies containing 10 mg of broad-spectrum CBD per gummy with added vitamins B12 and D3. They have been rated the best vegan gummies in VegNews, The Spa Insider, and more.

Sunday Scaries’ Bra Bearies contains 10 mg of broad-spectrum CBD and vitamin C to support your immune system. $2 of each bottle sold is donated to the breast cancer charity The Pink Agenda.

Sunday Scaries even has Holiday Scaries – limited-time holiday-themed cinnamon and spearmint 10 mg CBD drops containing L-theanine and B12.

Each bottle of Sunday Scaries CBD gummies has 20 gummies. The standard CBD gummies cost $29 per bottle, but the limited-edition gummies are $34 per bottle.

A subscription to Sunday Scaries products will save you 20% on your purchase.

Sunday Scaries offers a 100% money-back guarantee on their products, no questions asked.

How To Choose The Best CBD Gummies?

We’ve shared some of the best CBD gummies to choose from, but in the event that these aren’t your cup of tea, you should be armed with the knowledge of what to look for when buying CBD gummies. 

CBD Dosing

Beginners to CBD edibles may want to start with a low-dose gummy that contains around 10 mg of CBD per serving, then adjust the potency to suit your body’s needs. If you prefer choosing a CBD gummy with a higher concentration, it is possible to take only half of a gummy and work your way up.

Certificate of Analysis/Third-Party Testing of Hemp 

Reputable CBD companies should be transparent about their testing and have Certificate of Analysis (COA) easily available for all of their products, and even for individual batches.

Choose CBD gummies that have been third-party tested by ISO/IEC 17025 accredited laboratories tend to be of high quality.

A detailed COA allows you to confirm the purity and potency of the CBD used in your CBD gummy. The best reports will have extensive testing for adulterants like heavy metals, pesticides, and mycotoxins. 

Type of CBD Extract

Depending on your needs; you may want to choose a CBD gummy made with CBD isolate, broad-spectrum, or full-spectrum CBD.

CBD isolate is an extract with over 99% CBD, is free of THC, and does not contain significant amounts of other cannabinoids.

Broad-spectrum and full-spectrum CBD products contain other cannabinoids, terpenes, and flavonoids. Broad-spectrum CBD is free of THC, while full-spectrum CBD extracts have a concentration of 0.3% or less of THC. 

Some people prefer broad-spectrum or full-spectrum CBD products because of the “entourage effect[7].” The entourage effect means that the CBD, terpenes, flavonoids, cannabinoids, and THC (if present) have a synergistic effect and increase the benefits of the CBD.

Athletes should take caution with broad-spectrum and full-spectrum CBD oil gummies because the World Anti-doping Agency(WADA) considers other cannabinoids and THC as banned substances[8] although CBD is in the clear.

Botanical Ingredients 

It is easy to find CBD gummies that only contain CBD, but many CBD companies create products with added botanicals and ingredients for specific needs.

Pay attention to including botanicals to avoid any allergies or negative drug interactions. Speak with a healthcare professional before taking a CBD gummy containing botanicals to confirm whether there are any potential medical or safety risks.

Price

Consider your budget for a CBD gummy. Depending on your use, you may want to have a cost-effective CBD brand or a premium CBD gummy if you’re treating yourself. 

Potential Side Effects

There are a few potential side effects that can occur when you consume CBD gummies.

Common side effects[9] from taking CBD edibles are mild and generally include diarrhea, changes in appetite, changes in weight, and tiredness.

To reduce the likelihood of experiencing side effects, start with lower doses of CBD to find your tolerance.

CBD interacts with CYP450 enzymes[10]. These enzymes are necessary for the metabolism of medications, including antipsychotics, sedatives, and proton-pump inhibitors. Because the body of research on CBD is still limited, researchers do not know the full range of potential CBD-medication interactions. 

Final Thought

If you want to experience the benefits of CBD in an easy-to-manage way, then trying a CBD gummy may be for you. 

Current studies show that CBD can be effective for a number of conditions or can just be used to help you feel calmer during the day. Choosing CBD gummies with additional botanical ingredients can further support the effects of CBD.

Our list covers brands that offer some of the best CBD gummies on the market, but of course, this is not an exhaustive list. Using our recommendations above, you can also know how to choose high-quality CBD gummies.

Before you rush to try a new CBD gummy, always speak with your doctor before starting a new supplement to be sure that there aren’t any safety risks or potential medication interactions.

Frequently Asked Questions

How many CBD gummies should I take to feel the effects?

Everyone reacts to CBD differently and may have different CBD needs. Start with a low-dose gummy containing 10 mg of CBD or the recommended dosing on the gummy package. Gradually increase your dosage to find the concentration of CBD gummies that work best for you.

Are CBD gummies legal?

Because of the 2018 Farm Bill, industrial hemp containing less than 0.3% THC became legal to cultivate and made industrial hemp-derived CBD easier to obtain. The legality of CBD products for medicinal and recreational use differs between states, so check with your state’s laws before making a CBD gummy purchase.

Are there any side effects from taking CBD gummies?

Common side effects[11] from taking CBD edibles are mild and generally include diarrhea, changes in appetite, changes in weight, and tiredness. CBD may interact with medications, including antipsychotics, sedatives, and proton-pump inhibitors. 


+ 11 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Abuse, N.I. on D. (n.d.). What are marijuana’s effects on lung health? [online] National Institute on Drug Abuse. Available at: https://nida.nih.gov/publications/research-reports/marijuana/what-are-marijuanas-effects-lung-health.
  2. Lu, H.-C. and Mackie, K. (2016). An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry, [online] 79(7), pp.516–525. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4789136/ [Accessed 22 Feb. 2022].
  3. Bonaccorso, S., Ricciardi, A., Zangani, C., Chiappini, S. and Schifano, F. (2019). Cannabidiol (CBD) use in psychiatric disorders: A systematic review. NeuroToxicology, [online] 74, pp.282–298. Available at: https://pubmed.ncbi.nlm.nih.gov/31412258/ [Accessed 22 Feb. 2022].
  4. Burstein, S. (2015). Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. Bioorganic & Medicinal Chemistry, [online] 23(7), pp.1377–1385. Available at: https://pubmed.ncbi.nlm.nih.gov/25703248/ [Accessed 22 Feb. 2022].
  5. Boyaji, S., Merkow, J., Elman, R.N.M., Kaye, A.D., Yong, R.J. and Urman, R.D. (2020). The Role of Cannabidiol (CBD) in Chronic Pain Management: An Assessment of Current Evidence. Current Pain and Headache Reports, [online] 24(2). Available at: https://pubmed.ncbi.nlm.nih.gov/31980957/ [Accessed 22 Feb. 2022].
  6. Sultan, S.R., O’Sullivan, S.E. and England, T.J. (2020). The effects of acute and sustained cannabidiol dosing for seven days on the haemodynamics in healthy men: A randomised controlled trial. British Journal of Clinical Pharmacology, [online] 86(6), pp.1125–1138. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7256118/ [Accessed 22 Feb. 2022].
  7. Ferber, S.G., Namdar, D., Hen-Shoval, D., Eger, G., Koltai, H., Shoval, G., Shbiro, L. and Weller, A. (2020). The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders. Current Neuropharmacology, [online] 18(2), pp.87–96. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7324885/ [Accessed 22 Feb. 2022].
  8. Lachenmeier, D.W. and Diel, P. (2019). A Warning against the Negligent Use of Cannabidiol in Professional and Amateur Athletes. Sports, [online] 7(12), p.251. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6956040/ [Accessed 22 Feb. 2022].
  9. Iffland, K. and Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and Cannabinoid Research, [online] 2(1), pp.139–154. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5569602/ [Accessed 22 Feb. 2022].
  10. Zendulka, O., Dovrtělová, G., Nosková, K., Turjap, M., Šulcová, A., Hanuš, L. and Juřica, J. (2016). Cannabinoids and Cytochrome P450 Interactions. Current Drug Metabolism, [online] 17(3), pp.206–226. Available at: https://pubmed.ncbi.nlm.nih.gov/26651971/ [Accessed 22 Feb. 2022].
  11. Iffland, K. and Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and Cannabinoid Research, [online] 2(1), pp.139–154. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5569602/ [Accessed 22 Feb. 2022].‌

Written by:

Markita Lewis, MS, RD

Medically reviewed by:

Markita Lewis, MS, RD is a registered dietitian and a freelance health and wellness writer practicing in the Los Angeles area. As a clinician, Markita has several years of experience working with adult and pediatric patients in inpatient and outpatient settings. Markita has also conducted research in areas including diverticulosis, age-related macular degeneration, and cultural eating patterns.

Medically reviewed by:

Harvard Health Publishing

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Database From Cleveland Clinic Foundation

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WHO

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United Nations Global Compact
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Database from U.S. National Library of Medicine

U.S. Federal Government
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Trusted Source

Database From Department of Health and Human Services

Governmental Authority
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PubMed Central

Database From National Institute Of Health

U.S National Library of Medicine
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