Top 6 Best CBD Oil For Dogs With Cancer -Effective & Safe 2023

Kate Barrington

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Medically reviewed by Victor Nguyen, PharmD.

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Honest Paws cbd oil

Honest Paws CBD Oil

  • Wide range of high-quality products
  • Made with organic full-spectrum CBD
  • Third-party tested for safety and quality

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Joy organics cbd oil

Joy Organics

  • Organic broad-spectrum CBD oil
  • Completely free from THC
  • Available in treats and oil tincture

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Honest paws dog treat

Honest Paws Dog Treat

  • Choose from soft chews or crunchy treats
  • Made with organic full-spectrum hemp oil
  • Wide range of flavors to choose from

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There is a reason they say dogs are a man’s best friend. Our dogs are more than just pets – they’re members of the family. This is why it’s particularly devastating when they get sick. Keeping up with routine veterinary care and providing a nutritious diet are two of the most important ways to support your dog’s health. However, dogs can get sick even when they have the very best of care. 

In an English study on the prevalence of health disorders in dogs, 75.8% of canine participants[1] were diagnosed with at least one disorder during the study period. The conditions a dog is likely to develop over the course of its lifetime vary according to numerous factors such as breed, diet, and activity level. While some dogs are lucky enough to live long and healthy lives, the American Veterinary Medical Association (AVMA) reports that almost half of the dogs over the age of 10 will develop cancer. 

In this article, we’ll talk about the types of cancer seen in dogs and how CBD oil might be helpful in managing the condition. You’ll also see our top picks for the best dog CBD products.

Best CBD Oils For Dogs With Cancer In (June. 2023)

Hemp Oil For Dogs

Cancer treatment for dogs[2] can be difficult. Surgical removal of tumors is typically the first step, followed by chemotherapy and/or radiation. Even if these treatments are effective, they often come with side effects of their own. Loss of appetite, lethargy, diarrhea, and vomiting are fairly common side effects and some dogs experience lingering pain. 

Recent studies suggest that CBD oil may help improve the quality of life[3] for dogs undergoing cancer treatment. Though the effects of CBD on dogs are less well-studied than the effects on humans, small studies and anecdotal reports offer promising results. 

When it comes to CBD for dogs, there are many products to choose from. Dog CBD products are not all created equal, however, and it’s your job as a pet owner to shop smart. Read on to learn what to look for and to see our top 5 picks for CBD oil products for dogs.

Best CBD Oil For Dogs With Cancer 2023

Honest Paws CBD Oil

Honest paws cbd oil

Free shipping & 20% Off Coupon: HEALTHCANAL

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Choose from a variety of CBD oil products according to your dog’s specific concerns. All products are made with organic, full-spectrum CBD and come in a convenient dropper bottle for easy dosing.

  • Wide range of high-quality products
  • Made with organic full-spectrum CBD
  • Third-party tested for safety and quality
  • Can be tricky to find the right dosage
  • Price varies greatly depending on the concentration

Every dog is unique and it’s important to find a CBD oil that works for you and your dog. Honest Paws offers five different formulas, all available in at least three different concentrations according to your dog’s size. They even offer an “Extra Strength” option in their CBD oil for wellness. All of their products are competitively priced and orders over $49.95 ship free. 

Finding the right CBD product for dogs can be tricky, especially when dealing with a serious disease like cancer or the side effects of treatment[4]. Honest Paws offers formulas for pain relief, anxiety, mobility, and general wellness which makes it easy to find the perfect remedy. Their Wellness formula even comes in a Certified Organic version for maximum quality. 

When you choose Honest Paws, you’re choosing the best for your dog. Their products for pets use the same high-quality CBD as their products for humans, so you don’t have to compromise. Plus, you’ll enjoy a 30-day money-back guarantee with every order just to make sure you’re satisfied. Make a one-time purchase or save 15% with an auto-fill order.

Joy Organics

Joy organics cbd oil

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When administering CBD to dogs, it’s important to choose products that are safe and effective. Joy Organics CBD is not only high quality, but it is completely free from THC.

  • Made with CBD-rich hemp oil
  • Available in treats and oil tincture
  • Completely free from THC
  • Only two product choices for pets

Your dog is already dealing with the side effects of its cancer treatment, so the last thing you want to do is add more on top. Some CBD oils contain trace amounts of THC which can have a negative effect on your dog, depending on its size and sensitivity. If you’re looking for a THC-free solution, consider Joy Organics. 

Joy Organics offers two pet CBD options: CBD dog treats and CBD oil. Their dog treats are made with phytocannabinoid-rich hemp extract powder and contain about 2mg of CBD per treat. These premium-grade treats have an irresistible beef flavor and are easy to dose – just give your dog 1 to 2 treats per 25 pounds of body weight. Joy Organics CBD oil is formulated with organic olive oil and broad-spectrum CBD.

Honest Paws Dog Treats

Honest paws dog treat

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For dog owners concerned about dosing liquid CBD, these dog treats may be the perfect alternative. Choose from soft chews or crunchy treats in a variety of formulas.

  • Choose from soft chews or crunchy treats
  • Made with organic full-spectrum hemp oil
  • Wide range of flavors to choose from
  • Some flavors are more appealing than others
  • More expensive than some options

Finding the right dosage can be tricky when using CBD, especially if you’re using a liquid product. When it comes to CBD for support during cancer treatment, some dogs need a higher dose than others but it’s always a good idea to start low and work your way up. If you’re looking for a convenient way to introduce your dog to CBD, Honest Paws dog treats are a great choice. 

Honest Paws offers a variety of soft chews and crunchy treats in several tasty flavors including peanut butter, poultry, and coconut. These chews are made with organic full-spectrum hemp oil with naturally occurring CBD and other organic ingredients like organic oats, organic barley, and organic coconut shavings. Place a one-time order or save an additional 15% with an auto-refill and enjoy free shipping on orders over $49.95.

Spruce CBD

Spurce CBD

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Known for the quality of their human CBD oil products, Spruce CBD now offers a product specifically for dogs. This highly concentrated oil may be perfect for dogs with cancer to help address symptoms like pain, inflammation, and depression.

  • Highly concentrated formula (750mg)
  • Human lab-grade full-spectrum CBD
  • Made with coconut oil, no flavoring
  • Fairly expensive
  • Liquid CBD can be tricky to dose

When it comes to dealing with the side effects of cancer and cancer treatment, some dogs require a fairly high dosage – especially larger dogs. Spruce CBD is one of the most concentrated CBD oils on the market, containing 750mg of CBD per bottle. To administer the oil, simply follow the instructions on the label according to your dog’s body weight. 

Spruce CBD uses only 100% natural, lab-grade full-spectrum CBD. Their products are lab-tested for safety and quality, and they are made in the USA. This brand is free from pesticides and low in THC, tested under 0.3% THC. 
Another benefit unique to Spruce CBD is that the product is made specifically with dogs in mind. They’ve swapped out the hemp carrier oil for coconut oil[5] which has a milder taste and may be gentler on your dog’s digestive system. There are no other added flavors either, which makes it easy to administer on top of your dog’s food.

CBD Pure

Pure CBD dog oil

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If you’ve never tried CBD for your furry friend, you may be hesitant to spend a lot of money on it. CBD Pure makes a single tincture for dogs and it is affordably priced.

  • Made with organically grown CBD oil
  • Affordable pricing, discounts on multiple
  • Backed by a 90-day money-back guarantee
  • Dosing instructions could be more detailed
  • No free shipping offers are available

When it comes to managing your dog’s cancer, your biggest concern may be preserving your dog’s quality of life. When paired with cancer treatments, the anti-inflammatory benefits of CBD may help reduce pain while relieving other symptoms such as nausea and depression. CBD Pure is a beginner-friendly option that comes in a low concentration so your dog can get used to the product. You can easily increase the dose over time as needed. 

One of the benefits of CBD Pure is its affordable pricing. A single bottle costs just $24.99, but you can save by purchasing in multiples of three. You’ll save $2.50 a bottle by ordering three or nearly $5 a bottle by ordering six. Your first order is backed by a 90-day money-back guarantee.

Holistapet CBD Oil For Dogs

Holistapet CBD Oil For Dogs

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CBDfx is one of the few companies that has high-quality broad-spectrum CBD oil tinctures available for your pet. It’s easy to find the best dosage for your pet in a flavor they’ll love.

  • A large range of organic CBD concentrations is available
  • The brand has an advisory board made up of veterinary professionals
  • 30-day money-back guarantee
  • Conflicting information about CBD type on Holistapet’s website
  • Expensive CBD product

Holistapet is a pet wellness company that is dedicated to providing natural remedies to resolve pet discomforts. 

All of their products are third-party lab-tested, vegan, non-GMO, gluten-free, dairy-free, and made with 100% natural ingredients. Holistapet even has a board of Veterinary Advisors to help guide the development of their products.

Holistapet stands out by having five different potencies of their CBD Oil for Dogs & Cats available:

  • 150 mg CBD for small pets under 20 lbs, 5 mg CBD per serving
  • 300 mg CBD for medium-sized pets 20-60 lbs, 10 mg CBD per serving
  • 600 mg CBD for large pets 60-100 lbs, 10 mg CBD per serving
  • 1200 mg CBD for extra large pets 100-160 lbs, 40 mg CBD per serving
  • 3000 mg CBD for pets over 160 lbs, 50 mg CBD per serving

There is some conflicting information on the product page concerning whether their products contain full-spectrum or broad-spectrum CBD oil. After calling Holistapet’s customer service line, it was confirmed that Holistapet uses full-spectrum CBD oil.

Cannabis Oil For Dogs With Cancer 

Cancer accounts for roughly half the deaths[6] of dogs over 10 years of age. Though the cause of cancer is still being studied, new treatment methods are constantly under development and knowledge about the disease continues to grow. Different types of cancer manifest in unique ways, but many of the early signs tend to overlap.

Here are some of the most common signs of cancer in dogs:

  • Sores that fail to heal properly
  • Abnormally swelling
  • Loss of interest in food
  • Unexplained weight loss
  • Difficulty eating or swallowing
  • Hesitation to exercise
  • Difficulty breathing or urinating

Confirming a cancer diagnosis requires more than an observation of symptoms. Your veterinarian will need to perform additional tests to rule out other potential conditions and may perform blood work, urinalysis, and biopsies to confirm a cancer diagnosis. Once the diagnosis is confirmed, you can begin discussing treatment options. While talking to your vet about the options for treatment, you may want to ask about CBD for dogs.

What Is CBD Oil? 

Though you may be familiar with cannabis in the form of marijuana, this isn’t something you should offer your dog. Marijuana contains high concentrations of tetrahydrocannabinol (THC), a psychoactive compound that can be very dangerous for pets[7]. One of the other active ingredients in cannabis, cannabidiol (CBD), however, can actually be very beneficial.

Cannabidiol or CBD is not a psychoactive compound, so it doesn’t produce a “high” like THC. CBD has been used as a therapy for a variety of conditions[8] including pain management, anxiety relief, arthritis pain, and even seizures. Though the use of CBD for treating these conditions is still under-researched, there are small studies and anecdotal evidence to support each. 

How Does CBD Oil Work? 

The mechanisms through which CBD helps reduce inflammation and relieve pain are not fully understood. Scientific research regarding the use of pet CBD is limited, but certain hypotheses can be made from its effects in humans and other animals. Given existing research about the effects of CBD on people, veterinarians believe the benefits of CBD for dogs may be linked to its effects on the endocannabinoid system or ECS. 

The endocannabinoid system is present in all members of Animalia, including both humans and dogs. It is a complex cell-signaling system that helps maintain homeostasis[9] in the body by regulating important bodily functions including appetite, mood, memory, and sleep. 

The ECS contains two types of cannabinoid receptors: CB1 and CB2. Though these receptors are designed to interact with endocannabinoids (natural cannabinoids produced in the brain), they have been shown to interact with plant-derived endocannabinoids like CBD as well. The effects of CBD on the endocannabinoid system are vast and varied, but many are beneficial.  

What Benefits Does It Provide For Dogs With Cancer? 

Before giving your dog CBD oil, it’s important to understand that CBD alone has not been shown to be an effective treatment for cancer. Pet CBD is primarily used as a supportive therapy to promote general wellness and relief from symptoms. That being said, it could be a beneficial addition to your dog’s cancer treatment plan.

Here are some of the potential benefits of CBD oil[10]:

  • Reducing inflammation
  • Appetite stimulation 
  • Relieving or reducing pain
  • Anxiety and depression relief
  • Relief from nausea 
  • Slowed tumor growth

Cancer is a difficult disease to treat because it is not fully understood and because it can change and spread rapidly. One of the biggest potential benefits of CBD for dogs is related to its ability to slow the proliferation of cancer[11] cells. Though canine studies are limited, mouse studies[12] revealed that CBD combined with chemotherapy tripled survival rates in mice with pancreatic cancer. At the very least, many dog owners report improved quality of life in aspects of pain management, appetite stimulation, and relief from cancer treatment side effects. 

How Safe Is Hemp Oil For Dogs With Cancer? 

Before giving your dog anything – whether food, medication, or supplement, it’s important to understand what it is and how it works. Never give your dog anything new without your veterinarian’s approval. Even natural supplements can interact poorly with certain medications, and you want to make sure anything you give your dog is safe. 

When used properly, CBD is generally regarded as safe by respected organizations including the World Health Organization (WHO). Keep in mind that the majority of studies regarding CBD use are human trials, however, so it’s important to follow your veterinarian’s advice and to use your best judgment when choosing CBD products. 

When shopping for CBD oil, look for products made with high-quality, full-spectrum CBD[13]. Avoid products that contain chemical additives and make sure the product has been tested by a third party for safety and quality. Pet owners should keep in mind that different CBD products come in various concentrations, so you’ll need to follow the dosing instructions for the specific product.

How Much CBD Oil Should I Give My Dog For Cancer? 

Because using CBD for pets is still fairly unstudied, there is no standard dosage recommendation. When using CBD, pet owners should follow the dosing information on the product according to their dog’s body weight. 

Keep in mind that smaller doses are usually effective for general wellness and anxiety relief, but higher doses may be required for the treatment of more serious health problems such as cancer. Start with the lowest recommended dosage to see how your dog reacts and increase the dosage if needed. Talk to your veterinarian to make sure your dog’s current medications won’t be affected. 

Though CBD oil may not be a miracle cure for cancer, it could very well help relieve some of your dog’s pain and improve its quality of life. Just be sure to read the information on the label carefully and monitor your furry friend for side effects.

Frequently Asked Questions

Is CBD oil safe for dogs? 

Yes, it has been shown to provide a wide variety of health benefits ranging from general wellness support and anxiety relief to reducing seizure activity and slowing the spread of cancer.

Is CBD oil good for dogs with anxiety? 

Yes. CBD oil acts on the body’s endocannabinoid system to naturally soothe anxiety, stimulating the creation of serotonin which helps stabilize your dog’s mood.

What are the side effects that dogs can experience from taking CBD?

Some potential side effects dogs can experience from taking CBD include diarrhea, vomiting, increased liver enzymes, sleepiness, and increased appetite.

Is it possible to give a dog too much CBD?

No, not in a medical sense. There is no such thing as too much CBD for your dog. Cannabidiol (CBD) does not interact with receptors in the brainstem or areas regulating respiration except to reduce inflammation. Giving dogs too much CBD may result in side effects.

+ 13 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. O′Neill, D.G., Church, D.B., McGreevy, P.D., Thomson, P.C. and Brodbelt, D.C. (2014). Prevalence of Disorders Recorded in Dogs Attending Primary-Care Veterinary Practices in England. PLoS ONE, [online] 9(3), p.e90501. doi:10.1371/journal.pone.0090501.
  2. MU Veterinary Health Center. (2015). Cancer Treatment. [online] Available at:
  3. (2015). A pilot study to determine the safety and efficacy of CBD oil use during chemotherapy in dogs with lymphoma» Veterinary Research» College of Veterinary Medicine» University of Florida. [online] Available at:
  4. Cornell University College of Veterinary Medicine. (2017). Managing Common Side-Effects of Chemotherapy In Companion Animals. [online] Available at:
  5. Heinze, R. and Heinze, R. (2018). The Skinny on Fat: Part 2 – Essential fatty acids and inflammation. [online] Clinical Nutrition Service at Cummings School. Available at:
  6. Cancer, C. (2013). Canine Cancer. [online] Carlson College of Veterinary Medicine. Available at:
  7. Veterinary Medicine at Illinois. (2021). Marijuana and Pets Should Not Mix – Veterinary Medicine at Illinois. [online] Available at:
  8. Everett, M. (2017). CBD for Dogs: Everything You Need to Know. [online] Available at:
  9. Silver, R.J. (2019). The Endocannabinoid System of Animals. Animals, [online] 9(9), p.686. doi:10.3390/ani9090686.
  10. Kogan, L., Schoenfeld-Tacher, R., Hellyer, P. and Rishniw, M. (2019). US Veterinarians’ Knowledge, Experience, and Perception Regarding the Use of Cannabidiol for Canine Medical Conditions. Frontiers in Veterinary Science, [online] 5. doi:10.3389/fvets.2018.00338.
  11. Cornell University College of Veterinary Medicine. (2019). Examination of the Effects of Cannabidiol on Canine Neoplastic Cell Apoptosis/Autophagy and Potential for Chemotherapy Resistance or Sensitivity. [online] Available at:
  12. Ferro, R., Adamska, A., Lattanzio, R., Mavrommati, I., Edling, C.E., Arifin, S.A., Fyffe, C.A., Sala, G., Sacchetto, L., Chiorino, G., De Laurenzi, V., Piantelli, M., Sansom, O.J., Maffucci, T. and Falasca, M. (2018). GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine. Oncogene, [online] 37(49), pp.6368–6382. doi:10.1038/s41388-018-0390-
  13. Thomas Jefferson. 2018. What is Full Spectrum CBD? Available from:
Kate Barrington

Medically reviewed by:

Victor Nguyen

Kate Barrington holds a Bachelor’s degree in English and is the published author of several self-help books and nutrition guides. Also an avid dog lover and adoring owner of three cats, Kate’s love for animals has led her to a successful career as a freelance writer specializing in pet care and nutrition. Kate holds a certificate in fitness nutrition and enjoys writing about health and wellness trends — she also enjoys crafting original recipes. In addition to her work as a ghostwriter and author, Kate is also a blogger for a number of organic and natural food companies as well as a columnist for several pet magazines.

Medically reviewed by:

Victor Nguyen

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