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Best CBD Oil For Nausea: Top 4 Fast-Acting Choices In 2024

Kathy Shattler

Updated on - Written by
Medically reviewed by Kimberly Langdon, MD

All articles are produced independently. When you click our links for purchasing products, we earn an affiliate commission. Learn more about how we earn revenue by reading our advertise disclaimer.

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Best CBD For Nausea In (April. 2024)

What Is Nausea?

Nausea is an uneasiness in the stomach that usually occurs before vomiting. It’s an awful, queasy feeling that is annoying and unpleasant and may be referred to as an “upset stomach” or “motion sickness.” It can make you want to curl up in a corner and hide from the world. 

It can lead to uncontrollable bouts of vomiting or leave you feeling dizzy and giddy. Examples of severe nausea include that feeling you get from motion sickness from a car or airplane, taking pills on an empty stomach, eating too much or too little, or overindulging in alcohol.

Nausea is associated with decreased gastric motility and increased tone in the small intestine. Also, there is reverse peristalsis in the small intestine associated with the feeling of nausea. Peristalsis is a series of wave-like motions that move food down the digestive tract. Reverse peristalsis would cause food to move out of the digestive system through vomiting, such as toxin-induced nausea from food or motion sickness.

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This innovative company, which started in 2015, hosts a wide variety of products that it sells nationally and internationally.

  • Wide variety of potencies
  • High-quality Kentucky hemp
  • Organic hemp
  • Important information not readily available
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CBDfx extracts its oils from hemp grown in Europe or Kentucky, where it is then shipped to southern California for further processing. CBDfx uses organic farming techniques and CO2 extraction to guarantee the most refined CBD oils it can produce. CO2 is widely considered the safest option for the extraction of hemp.

CBDfx manufactures full-spectrum oil. Thus, you are guaranteed the entourage effect that enhances the beneficial functions of CBD. Full-spectrum means you have the advantage of the terpenes, flavonoids, and cannabinoids, including CBG and CBN. Also, it has MCT oil in it for added nutrition. THC is at a compliance level of less than 0.3%.

 The product line is widely diverse, from those supplements made for pets’ use to those for the use of the rest of us like tinctures, oils, drinkable shots, sublingual strips in fun flavors, and capsules. CBD treatment can be fun and full of variety.

 A third-party lab analyzes contents and a Certificate of Analysis is available.

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Spruce is a family-run CBD brand that offers high-quality, lab-tested, full-spectrum CBD oil made from one of the finest, oldest hemp strains in the United States.

  • Third-party tested
  • Unique strain of organic hemp
  • Family-run business
  • No pesticides
  • Full-spectrum
  • Limited product range
  • Costs more than average

Established in 2018, Spruce is a CBD brand based in Raleigh, North Carolina. The company prides itself on making American-made CBD products. Spruce stands out from the competition in several ways. For instance, it’s a family-run business, which is unusual in the CBD industry.

Its CBD is sourced from a time-tested strain of hemp that’s been cultivated in the United States for over two hundred years. The CBD oil is harvested from organically grown hemp from farms in Kentucky and North Carolina.

Spruce stands out by employing a moonshine (alcohol) extraction process to isolate CBD-rich extracts from hemp for their hemp-derived CBD products. Although most CBD companies use CO2 extraction, alcohol extraction is just as safe and effective treatment. 

Spruce’s CBD oil is made with a lab-tested hemp extract, and it provides all of the cannabinoids, terpenes, and other beneficial compounds found in this cannabis plant. The THC content is <0.3%.

It has a pleasing peppermint taste and comes in 30 ml bottles with two CBD potencies: 25 mg of CBD per ml (750 mg total) and 80 mg of CBD per ml (2400 mg total).

Like all reputable CBD companies, Spruce provides comprehensive third-party test reports to confirm its CBD oils’ safety and potency. Besides working well on adults, Spruce CBD is also safe for kids, which makes it one of the most popular choices on the market.

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Joy Organics specializes in broad-spectrum CBD products, containing all of the beneficial components of hemp except THC. If you want to maximize CBD’s beneficial impact while avoiding THC, this brand is a great choice.

  • THC-free, broad-spectrum
  • Gluten-free
  • High-quality Colorado hemp
  • Low levels of minor cannabinoids

Joy Organics’ products offer a high level of bioavailability with its nanotechnology-generated CBD hemp oil. Nanotechnology allows the cannabinoid molecule to be broken down into smaller sizes easier to absorb. While most CBD oil has between 150 and 500 nanometer particles, Joy Organics CBD oil products contain just 25-60.

The company uses a proprietary hemp extraction method that produces 112 minor cannabinoids but remains THC-free. It is a broad-spectrum oil that contains all the plant’s terpenes, cannabinoids, and flavonoids without THC. 

Using CBD oil extracted from hemp grown in Colorado, Joy Organics produces some of the best CBD products on the market that are also gluten-free.

All products are subjected to in-house and lab-tested analysis producing Certificates of Analysis and a Certificate of Quality Assurance and remain free of harsh chemicals and metals.

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CBDPure hosts a wide range of products made from lab-tested hemp at an affordable price.

  • Organic hemp
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  • Affordable
  • Limited potencies

From soil to oil, this hemp is lab-tested and has a Certificate of Analysis that is downloadable at any location. The third-party lab testing guarantees that the best CBD oils produce quality CBD at a price you can afford. If prices are still too steep, they offer coupons you can use at check-out.

The company offers a 100% money-back guarantee if you return the products within a 90-day time frame if you are not satisfied.

Their line of hemp oil products is grown without pesticides or herbicides guaranteeing you a wholesome source of the best CBD possible. 

CBD products are made from hemp oil that contains a variety of cannabinoids, terpenes, and flavonoids extracted from the whole plant. It has less than 0.3% THC.

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The company provides a wide range of vegetarian CBD products that are gluten-free and contain the minor cannabinoid, CBDA.

  • Gluten-free
  • Non-GMO
  • Vegetarian
  • Contains CBDA
  • Limited potencies to choose from

PlusCBD products are full-spectrum products that also contain the cannabinoid CBDA. CBDA is known for its anti-inflammatory properties. CBDA is the raw, unheated version of CBD. In a study in rats, CBDA was a thousand times more potent than CBD[1] in binding to specific serotonin receptors linked to anti-anxiety and anti-nausea effects when administered alongside low-doses of the traditional anti-nausea drug for chemotherapy treatment patients, ondansetron. CBDA may be more desirable in treating nausea and upset stomachs than using CBD oil.

CBD products include soft gels, CBD gummies, drops, sprays, lotions, creams, balms, and roll-ons. The wide variety of products leaves a lot of the best choices for your CBD therapy. Sprays and drops may work better for an upset stomach, although taking the soft gels with food may help. There are no up-to-date studies on the effects of topical CBD on an upset stomach or nausea caused by vomiting.

All products come from agricultural hemp and industrially grown hemp, thus guaranteeing the best CBD possible. Industrially grown hemp is used to manufacture rope, fuel, and textiles.

 A third-party lab carries out an analysis of the contents of products.

What Causes Nausea? Other Potential Reasons

Dealing with nausea can be annoying. Many things can cause nausea. Some people who have experienced the effects of nausea are particularly sensitive to motion sickness, food poisoning, other medications, or the effects of certain medical conditions or treatments. Other nausea caused-conditions include:

  • Early stages of pregnancy
  • Emotional stress
  • Intense pain
  • Gallbladder disease
  • Infections
  • Reactions to certain smells
  • Ulcers
  • Brain tumors that affect the nervous system
  • Bowel obstruction
  • Appendicitis
  • Ingestion of excessive amounts of alcohol

The side-effect of nausea does not always lead to vomiting. For example, anxiety-induced nausea rarely leads to vomiting but is unpleasant, nevertheless, and will often lead to an upset stomach.

Is It Safe To Use CBD As A Nausea Remedy?

According to the World Health Organization (WHO) any reported side effects of CBD may be due to drug-drug interactions. WHO considers CBD to be a safe alternative treatment for many ailments and states it shows no addictive tendencies.

CBD products that undergo third-party lab testing and can produce a Certificate of Analysis demonstrate that their CBD products are safe for use by the consumer don’t contain any harmful pesticides or metals and are the best CBD products from seed to soil.

A look at the table of contents will tell you what is in your CBD product and if there is anything in the product that will make you nauseous, such as gluten. Labels should be scrutinized to make sure your product is safe.

Side Effects Of CBD For Nausea

Some of the best CBD oil products may give you an upset stomach if your dose is too high. A high CBD intake may not agree with you, the dose may be too high for your body, and your body seeks to eliminate it through an upset stomach, nausea, vomiting, and diarrhea. These symptoms are not uncommon with oils and supplements, especially if you ramped up your dose too quickly, not giving your body enough time to adjust. Or, there could be something in the product that is aggravating your digestive system, such as the carrier oil used or gluten.

Tiredness and changes in appetite[2] and weight may occur. There may be some drowsiness and light-headedness. Drug interactions may occur since CBD interacts with competing enzyme systems used in drug detoxification and metabolism. Other studies[2] have shown that treatment with doses of CBD oil up to 600 mg did not affect heart rate or blood pressure.

How To Use CBD Oil For Nausea

The fastest way to get CBD into your bloodstream is through inhalation. If you are struggling with nausea, you probably don’t want to take something orally, and you want it to be fast-acting. Using a vaporizer to breathe the oil as steam will allow you to feel the effects within 30 seconds or less. If you intend to vape your oil, make sure you buy from reputable sources from a supplier with lab-tested cartridges of CBD oil to help you get rid of your nausea. 

Adding a little THC to the therapy may help the nausea CBD is treating by binding to the endocannabinoid system’s CB1 receptors and nausea relief by this mechanism. CB1 receptors are present in the brain and central nervous system. Thus, whether full-spectrum, broad-spectrum, or isolated, CBD’s form may make a difference in therapy outcomes

Frequently Asked Questions

Is CBD oil good for nausea?

A study in the British Journal of Pharmacology suggested that CBD[3] may be beneficial in alleviating chemotherapy-induced nausea and vomiting. If it is useful for causes of nausea induced by medical treatments, chances are it will help nausea caused by other factors. CBD may help get rid of an upset stomach.

Where do you put CBD for nausea?

The best place to put CBD for nausea is in your lungs by steam inhalation or vaping to bypass your upset stomach. The next best site would be to use a spray or tincture that you put under your tongue for absorption into the bloodstream bypassing the digestive system.

What is a good dosage for CBD for nausea?

Always start low and go slow. Try reading the label for directions or asking a healthcare provider what the best starting dose would be for your condition.


+ 3 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Rock, E.M. and Lucy Anne Parker (2013). Effect of low doses of cannabidiolic acid and ondansetron on LiCl-induced conditioned gaping (a model of nausea-induced behaviour) in rats. British Journal of Pharmacology, [online] 169(3), pp.685–692. doi:https://doi.org/10.1111/bph.12162.
  2. Iffland, K. and Franjo Grotenhermen (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, [online] 2(1), pp.139–154. doi:https://doi.org/10.1089/can.2016.0034.
  3. Parker, L.A., Rock, E.M. and Limebeer, C.L. (2011). Regulation of nausea and vomiting by cannabinoids. British Journal of Pharmacology, [online] 163(7), pp.1411–1422. doi:https://doi.org/10.1111/j.1476-5381.2010.01176.x.
Kathy Shattler

Medically reviewed by:

Kimberly Langdon

Kathy Shattler has been a Registered Dietitian for over 25 years and currently runs her own Telehealth Clinic while freelance writing in her spare time. She graduated with a Master of Science degree in Human Nutrition from Michigan State University and has a plethora of experience in both clinical nutrition as well as public health. She has been deemed a trailblazer in her profession and continues to strive for excellence in public health education in integrative medicine and in her professional writing career.

Medically reviewed by:

Kimberly Langdon

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