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5 Best CBD Vape Cartridge To Buy 2023: Prefilled & Refillable Brands

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Medically reviewed by Kimberly Langdon, MD

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cbdfx vape catridge


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Vaping has become one of the most popular ways to use CBD. It may also be the best way to consume CBD. It is one of the fastest-acting methods and when you use a CBD vape, more of the CBD enters your system, compared to edibles or topicals. It also shouldn’t cause many of the health problems that are linked to smoking.

Of course, there are some potential disadvantages to vaping as well. When buying any sort of CBD product, you should always be wary of substandard products. It’s also natural to wonder if vaping really is less damaging to your health. Sorting out cartridges, lab testing, and vape juice can be bewildering. However, with just a little information on the best CBD vape cartridge here, you can start making informed decisions about what’s best for you.

Best CBD Vape Cartridges on the Market in 2023

What Are Vape Cartridges?

Vape cartridges, or vape carts as they are sometimes called, are glass container that contains CBD oil. The standard sizes are either 1 gram or half a gram, of CBD oil. 

CBD vape carts have a mouthpiece at one end and the threading for the battery at the other. Inside the vape cart, with the oil, is the atomizer. This heats up the oil, turning it to vapor in the same way that water turns into steam. 

Vape carts can sometimes leak. However, they are simple enough that there isn’t a lot that can go wrong with them.

Types of Vape Cartridges

Though CBD vape carts tend to be broadly the same, there are a couple of different types to consider. 


The standard vape cart you find at your local gas station or vape shop will probably be prefilled. As the name implies, the vape cart comes loaded with CBD vape oil. All you have to do is screw it into the battery and start puffing. 

It is sometimes possible to screw the mouthpiece off and refill the vape juice. It’s not something they’re really made for, however.


As you might guess, these vape carts were made to be refilled. They are largely the same as the pre-filled vape carts, except the mouthpiece screws on and off more easily. 

These can be a great option if you’re looking for ways to vape CBD on a budget. Many brands offer vape juice for use with refills, often with eye droppers to make things easy. Bottles of vape juice tend to be less expensive than buying individual vape carts each time. 


Pods are vape carts that are designed to be used with a single brand of battery. The most well-known is the Juul vaporizer and pod, with a few CBD options available for that battery.

In general, these tend to be more expensive. They usually aren’t refillable and in some ways may be less vulnerable to counterfeiting, though that’s not a guarantee[1]

At the moment, the standard vape carts are more common, though pods start taking the lead as larger companies start selling CBD products.

How To Find A High-quality Vape Cartridge?

Sometimes you’re just looking for some quick advice and a few tips. Here are 3 things to keep in mind when trying to find a high-quality vape cartridge.

  • Lab testing. CBD products can be of dubious quality sometimes, so reputable brands have begun offering lab tests, showing the different amounts of CBD, THC, and other compounds. 
  • Broad Spectrum vs. Isolate. Broad-spectrum CBD contains several cannabinoids[2], in the (unsupported[3]) belief they will be more effective together. Isolate contains only CBD in a more concentrated form. 
  • Choose Unflavored. Artificial flavorings are the compounds most likely to cause health problems.

The Line Up At A Glance

cbdfx vape catridge

Editor’s Choice


  • Designed to be used with CBD
  • Simple and straightforward
  • Reusable for long-term use

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Delta Extrax

Most Potency

Delta Extrax

  • No additives
  • Full-spectrum CBD
  • Free shipping

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Just CBD Vape Cartridge

Most Variety


  • Wide range of popular flavors
  • Options with no additives or flavorings
  • Third-party lab tested

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secret nature vape pen

Most Environmentally Friendly

Secret Nature CBD

  • Natural and organic
  • High-quality and environmentally friendly
  • No additives or flavorings

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Funky Farms

Best Disposable Pen

Funky Farms

  • Highly concentrated lab-grade CBD 
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Top 5 Best CBD Vape Cartridge 2023

CBDfx Vape Kit

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See CBDfx Reviews

A lot of people start with disposable vape pens, but they’re not the only option. This kit makes it easy for beginners to get their own setup they can use with any sort of CBD vape oil.

  • Simple to use
  • Ideal for beginners
  • Designed for CBD vape juice
  • A little expensive
  • Limited options

A higher temperature may seem like it should vape more oil faster. What it actually does is burn the CBD vape oil, make the vapor more irritating, and potentially cause some health problems. 

CBDfx’s vape kit prevents that from happening, with only one heat setting, perfect for use with CBD vape oil. It’s simple to use and great for beginners, enough that it’s probably worth the slightly higher price. 

Delta Extrax Natural Vape Cartridge

Delta Extrax

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See Delta Extrax Reviews

Flavorings and additives can make CBD vaping more attractive for some people, but many are just looking for medicinal value. Savage CBD Natural CBD vape is just CBD and terpenes.

  • No additives
  • Full-spectrum CBD
  • Free shipping
  • Third-party lab tested
  • Higher price

Vaping is an effective and generally safe way to take CBD. Some CBD vape cartridge brands add chemicals for flavor or other reasons, and in doing so increase the health risk.

Savage CBD offers some of the best CBD cartridges because they only contain CBD and other hemp derivatives. Reducing the additives can take a lot of the risk out of vaping, so you can find relief without worry.

Just CBD Vape Cartridge

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Coming in either 1000mg or 200 mg options, these CBD vape cartridges offer the flavor of vaping well-known cannabis strains. With no THC, however, they’re totally legit.

  • Variety of flavors
  • Natural options offered
  • Third-party lab tested
  • Some options include PG and flavorings

JustCBD has a range of CBD vape cartridges that are derived from well-known strains of cannabis. They say they can offer the experience of vaping those strains, but legally and without the THC.

Full-spectrum CBD vape oil contains cannabinoids and other compounds called terpenes. The terpenes are what naturally flavor CBD, so the vape oil could have the same flavoring as the strain it’s derived from.

JustCBD also offers a number of flavored options, like lemon, watermelon, and grape. They are a little less expensive but are made with PG and artificial flavorings.

Secret Nature CBD Vape Oil

secret nature vape pen

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See Secret Nature Reviews

Secret Nature CBD offers an ‘artisan CBD’, small batches made from high-quality ingredients. With larger amounts of vape oil and a wide range of strains, you should get your favorite while you can.

  • Offered in several strains
  • Natural and organic
  • Third-party lab tested
  • Larger amounts than standard
  • More expensive
  • Frequently sold out

Secret Nature CBD vape oil is made in small batches from hemp extract grown by the company. They use a controlled environment and strict methods to make the end product as potent as possible.

Experienced vapers may appreciate the wider range of Secret Nature CBD vape oil strains. Newcomers can appreciate the environmentally friendly and organic approach. The small batch size does mean that supply goes fast.

Funky Farms

Funky Farms

15% Off First Order

Sometimes messing with vape juice, batteries, and cartridges is a pain. Funky Farms offers a ready-to-use pen full of natural CBD vape oil, with no additives or flavorings.

  • No additives
  • Ready to use
  • Third-party lab tested
  • More expensive
  • Disposable pen

The upside with disposable vape pens is that you don’t have to worry about CBD vape oil or cartridges. Everything is in one unit and all you need to do is press a button. Many disposable vape pens are cheap and heavily flavored.

Funky Farms offers a vape pen that’s easy to use, but without additives and flavorings. The vape pen is filled with only hemp products. It doesn’t even have the PG most other vape pens use.

This vape pen is at the pricier end of the market. However, you get what you pay for and Funky Farms natural vape pens might be worth the cost.

Can CBD Cartridges Show Up On A Drug Test?

This question isn’t as simple as it might appear. At the moment, employment drug tests don’t test for CBD. CBD has never been shown to impair judgment, so there’s no liability if a worker uses it.

However, the CBD market is generally somewhat unreliable at the moment. It’s not unusual[4] for CBD products to have more or less CBD than is claimed on the label. 

A bigger problem is that they sometimes are wrong about the amount of THC as well. Federal law prohibits anything over 0.3% THC, but products with higher amounts sometimes are sold, unknowingly or otherwise.

Finally, even small amounts of THC vape oil can build up over time. This is particularly true if you’re using larger doses to manage pain or for other therapeutic purposes. 
There are reports of people running into problems at work or even losing their jobs[5]. However, if you’re confident the label is accurate and you’re using CBD only occasionally, you may be less likely to run into difficulties.

How To Buy The Best CBD Vape Cartridge?

Unfortunately, impulse buying a CBD vape cartridge or another CBD product is probably not a good idea. The best way to ensure you’re getting a high-quality, accurately labeled, and safe CBD vape cartridge is to do a little research first. There is a range of things that you want to look for which can single out less reputable brands.


Third-party lab testing is a good place to start when trying to find the right CBD cartridge for your needs. 

The CBD market was really created just a few years ago. As a result, while CBD products were generally legalized, there still isn’t a lot of regulation about producing and selling those products.

The result is that you can’t always trust what’s on the label. Depending on the type of product, there might be a 20% or more difference between the amount on the label and the amount actually present. 

CBD oils and vape juice tend to be more accurate, but they still can be a big disparity. This can be a real problem when there is less CBD, or even more so when there is more THC than on the label.

As a solution, many brands have begun to offer the results of an analysis of their product, provided by an impartial lab. The idea is that by doing so, they’ve proven their products are exactly what they claim. It’s not necessarily foolproof, but it does improve your odds.

Hemp Source

CBD is derived from the hemp plant. Growing hemp was strictly controlled in the United States up until 2018. It is still heavily regulated, but more growers were given permission to cultivate it. 

This has fueled the boom in CBD products in the past few years. However, the demand for CBD continues to grow at a high rate, while there are still a limited number of growers.

The quality of the hemp can impact the quality of the vape juice you buy. Pesticides or other chemicals that came into contact with the hemp can also find their way into your vape. 

Unfortunately, to meet the demand some CBD producers are getting the raw material, the hemp plant, from less reliable sources. As a result, the quality of their products might be substandard.

Whenever possible, you want to buy a product that is derived from US-grown hemp. The heavy regulation means that the quality tends to be high 

Extraction Method

CBD can be extracted from hemp in a couple of different ways. All of them involved breaking the hemp down so the CBD can be separated.

The standard method for the CBD industry has become CO2 extraction. This method uses CO2 at a very high pressure, which then is easily removed. 

The end product ends up being concentrated and pure, with little opportunity for contaminants. If you’re trying to decide which vape cartridges to buy, go for the one made using a CO2 extraction.

There are several other methods, but the other common one is solvent extraction. This uses a chemical to break down the hemp, which then has to be separated. The chemicals can often be toxic and if it’s not completely separated, it ends up in your vape juice.


Vape juice contains CBD of course, but there are also a few other ingredients. There is what’s called carrier oil, which is what makes up the majority of vape juice. Usually, it’s one of two things, propylene glycol or vegetable glycerin. There may also be flavorings or other additives, depending on the brand and type.

All of those ingredients are considered safe to eat by the FDA, but we have only a general idea of the effect they have when vaped. Inhaling a type of sweetener that was used in some vapes led to a particularly nasty lung condition, for example.

Additionally, adding a lot of heat can often lead to some changes in the chemical makeup of vape juice. Turning the heat up really high can turn some of the propylene glycols into formaldehyde and some other nasty things. Remember to keep your vape at the recommended temperature, even if the puffs aren’t as big.

In general, however, it might be wise to stick with unflavored CBD with the fewest additives. As with food, the fewer unknown chemicals you put in your body, the better.

There are also two general types of CBD out there. One is full-spectrum, or broad-spectrum, CBD. It includes several other cannabinoids, compounds from hemp, in addition to CBD. 

This is supposed to intensify the effect, making it more potent. The evidence for that is a little thin, though it’s true that the other cannabinoids may have additional helpful effects.

The other option is CBD isolate, which is basically just CBD without any other cannabinoids.


There is a range of prices when it comes to CBD vapes, usually depending on the concentration of CBD. As you might expect, higher concentrations tend to cost more, though it’s sometimes possible to find a deal.

CBD doesn’t have an intoxicating or narcotic effect, so there may be no real downside to taking a stronger dose. It will have a stronger effect more rapidly.

That can add up quickly, however, and you may opt for a lesser concentration. It depends on your tolerance and use.


Buying online may be the best way to go, but it’s not the only one. It may also not always be possible. Without the chance to read reviews or check reports, it might seem tough to sort out the high-quality CBD cartridges from stuff you should avoid.

In general, if a cartridge looks low quality, you should probably pass. That goes for packaging as well. Packaging that shows animated characters, or anything along those lines, is probably also of lower quality.

You can also look at the vape cartridge and vape juice itself. The juice should be light gold in color and be fairly thick. Darker vape juice, or runnier vape juice, is probably less concentrated and might be unsafe.

Most of the health problems associated with vaping have come from lower-quality cartridges. If you can’t be sure of the quality of the vape cartridge, you might be better off not buying it. Stick with higher-quality CBD vape cartridges.

How To Use A Vape Cartridge?

While they may seem like fancy gadgets, vape cartridges are actually pretty easy to use. You basically only need two things:

  • A vape cartridge
  • A vape battery

The cartridge screws into the battery, which then heats the vape juice until it turns into vapor. There are some battery/vape cartridge combinations that have to be used together, like the Juul pod. 

However, for the most part, vape cartridges and batteries have been standardized at the 510 threading. That means you can use most batteries with most vape cartridges without worrying.

Once the two halves are together, it’s easy to take a few puffs. Make sure the battery is on, then press the activation button and breath in gently. It’s best to start with smaller puffs and to stick with just two or three at a time, at least when you start. 

Many batteries will come in various settings, letting you change the colors or lights, the temperature of the vape, or other things. One thing to be wary of is overheating a vape cartridge.

Heating a vape cartridge up too much can start adding some toxic chemicals to the vapor. People do this most frequently to get the last few puffs out of an almost empty cartridge.

Restrain the temptation to do so. That residue may not be good for you to vape. Instead, when the vape juice gets darker and the vapor begins to taste more like burning, it’s time to stop. Even if there is a little juice still in there.

Benefits Of CBD Vape Cartridges

Just looking at a  few search results may lead you to believe CBD is a wonder drug, able to soothe pain and cure cancer. While the benefits of CBD may not quite live up to the hype, there is solid evidence that it does have some benefits.

Vaping may have the opposite problem. It wasn’t so long ago that federal agencies were issuing warnings about toxic vaping experiences. However, there is some evidence that it may actually be a great path for taking medications.

The arguments for both of those issues could fill books on their own. The broad outlines, however, can help you make some informed decisions.

What Is CBD?

Cannabidiol, better known as CBD, has become the focus of a lot of attention, as studies have linked it to a number of health benefits. A study of CBD and other cannabinoids revealed the endocannabinoid system in the human body. This system uses compounds similar to cannabinoids but created as used in the body.

The endocannabinoid system is involved in a bunch of different functions, from immune response to regulating mood. CBD should be able to take the place of some of the endocannabinoids.

Studies seem to confirm that it can, as preliminary studies have shown that CBD can have several benefits, including:

CBD may also have some neuroprotective effects, reducing the chances of conditions like Alzheimer’s. With most of these benefits, additional study needs to be done before we can say we understand what benefits the benefits of CBD are. It’s plain that it can help in many ways, however. 


While there has been some news in the last few years discussing the dangers of vaping, there are a few advantages to it as well. In fact, some researchers have concluded vaping could be an effective, new way to take medication.

One study[6] found that the best way to consume CBD for therapeutic purposes was by vaping. The only exception is when the vape is at too high a temperature. At that point, toxic chemicals can start forming.

Otherwise, vaping may be the way to get the highest dose of CBD, as quickly as possible. When it is inhaled, it can enter your bloodstream directly from your lungs. That’s true for smoking too, though, of course, that has a number of health hazards. 

Potential Side Effects

In the same way that more science needs to be done before we know all the benefits of CBD, we also don’t really know what all the side effects may be. A few studies have indicated that CBD may impact you negatively in some ways.

A study done on mice showed that CBD could be linked to liver damage, for example. Most side effects are far less serious, including dry mouth, reduced appetite, fatigue, or drowsiness. CBD may also interact with blood thinners like coumadin in a dangerous way.

Vaping can also potentially have some negative side effects. Most of these have been associated with ‘counterfeit’ CBD vape cartridges, not made by a reputable company.


Many people are already using CBD for things like pain relief, reducing anxiety, insomnia, and a range of other things. They’re finding it helpful, so there is little doubt that CBD does have some benefits.

While there is still more science to do, it seems as if it is a safe and effective treatment for many ailments. Vaping, done within certain guidelines, may be the most effective way to take a dose of CBD.

Frequently Asked Questions

Can CBD really help?

Preliminary studies seem to indicate CBD has many potential benefits. There is also overwhelming anecdotal evidence that it can help in many ways.

Does vaping CBD have any side effects?

CBD seems to have few serious side effects. Side effects usually include things like drowsiness, dry mouth, or loss of appetite. It can interact negatively with blood thinners, which can be serious. Vaping may also have some potentially negative side effects.

What kind of battery do I need for CBD vape cartridges?

Most vape cartridges use the 510 thread standard, so in most cases, any vape cart can be used with any battery. The exception is proprietary ‘pods’, like Juul pods, which can only be used with that brand’s battery.

Can CBD show up on a drug test?

Employment drug tests are looking specifically for THC, as it’s illegal and is considered to impair judgment. CBD is not tested for/ However, some CBD products can have amounts of THC in them. Small amounts of THC can also build up over time, which can lead to a positive result for THC.

Is vaping bad for you?

In general, vaping should be largely safe. There are several things that can make it riskier, however. First, be sure you’re buying from a reputable brand and seller. Second, sticking to unflavored vape juice may be best. Third, don’t turn up the heat too high or try to get the last bit of juice out.

+ 6 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Manskar, N. (2020). Counterfeit Juul e-cigarette manufacturer busted in China. [online] New York Post. Available at: https://nypost.com/2020/10/30/counterfeit-juul-e-cigarette-manufacturer-busted-in-china/.
  2. Adf.org.au. (2022). Cannabinoids – Alcohol and Drug Foundation. [online] Available at: https://adf.org.au/drug-facts/cannabinoids/.
  3. Expert Review of Clinical Pharmacology. (2018). The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy. [online] Available at: https://www.tandfonline.com/doi/full/10.1080/17512433.2020.1721281?scroll=top&needAccess=true.
  4. Barcott, B. (2019). Are you getting the CBD you paid for? We put 47 products to the test. [online] Leafly. Available at: https://www.leafly.com/news/strains-products/cbd-oil-test-results.
  5. Gill, L.L. (2019). Can You Take CBD and Pass a Drug Test? [online] Consumer Reports. Available at: https://www.consumerreports.org/cbd/can-you-take-cbd-and-pass-a-drug-test/.
  6. Varlet, V., Concha-Lozano, N., Berthet, A., Plateel, G., Favrat, B., De Cesare, M., Lauer, E., Augsburger, M., Thomas, A. and Giroud, C. (2016). Drug vaping applied to cannabis: Is ‘Cannavaping’ a therapeutic alternative to marijuana?. Scientific Reports, [online] 6(1). doi:10.1038/srep25599.‌

Medically reviewed by:

Kimberly Langdon

Sean Newton has nearly ten years of experience as a health and fitness writer, focusing on diet and its effects on your health. He also is an avid athlete and martial artist, specializing in bodyweight exercises and movement training. Together with an evidence-based approach to good health, his goal is to lay out the facts for readers, so they can make informed choices.

Medically reviewed by:

Kimberly Langdon

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