Uqora Reviews 2023: Does This Supplement Prevent UTIs?
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9.0
Quality
9.0
Brand’s Transparency
8.0
Value
Features
- Three-part proactive regimen to help prevent UTIs.
- Prevention strategies for urinary tract infections.
- Probiotics for women’s reproductive health.
Brand Information
- Created to help prevent urinary issues.
- Backed by physicians and scientists.
- Includes science-backed ingredients.
Medical Benefits
- Prevents UTIs.
- Promotes vaginal microbiome.
About The Brand
Uqora, a company that focuses on urinary health, was started by Jenna Ryan and her partner, Spencer Gordon, as Jenna struggled with recurrent urinary tract infections–UTIs. Not finding an immediate solution to the problem, they built Uqora in collaboration with health professionals.
A company that provides products for urinary health but is also committed to delivering UTI education and innovation in products and has a three-part proactive regimen; these three products together can help improve the health of the urinary system.
Cranberry juice or cranberry extract products are a specific sought-after solution[1] to uncomplicated UTIs. Uqora uses a combination of vitamins, minerals, probiotics, and natural extracts to promote overall urinary tract health.
Besides the three-part proactive regimen, Uqora also sells a UTI emergency kit for immediate relief before a doctor visit can be arranged, wipes, and a ph-balanced vulva cleanser to support vaginal health. Read on for our Uqora reviews of the three-part regimen.
Is Uqora Safe?
Uqora’s active ingredients are safe to consume and naturally found in foods. Although, it’s important to consult with your physician if you are diagnosed with chronic health conditions, especially if prescribed medications.
Some medications may be negatively affected, and you should consult your physician or pharmacist before using Uqora’s products.
Pros
- Controls and promotes a healthy urinary system.
- Includes vitamins and minerals.
- Manages microorganisms in the bladder, like E.coli.
- Natural ingredients.
Cons
- The regimen of three supplements is individually priced.
- The supplement, Promote, is not designed for men.
- No evidence of third-party lab testing.
Best Seller Uqora Products 2023
Flush

Flush one of Uqora’s products with vitamins and minerals to help maintain the urinary tract. It comes with seven main ingredients that each help contribute to the health of the urinary tract.
- Contains vitamins and minerals.
- Antibiotic-free.
- Pink lemonade flavor.
- A diuretic.
- Contains stevia.
Flush a drink mix in powder form with pink lemonade flavor.
The ingredients are D-mannose, a simple carbohydrate commonly found in foods. D-mannose is a simple sugar similar to glucose and helps bind microorganisms and flush them out of the urinary tract.
Potassium citrate and citric acid help with alkalizing urine. Both of these ingredients[2] are generally recognized as safe.
Vitamin B6, an essential vitamin, is added as a natural diuretic.
Magnesium is added to replace the magnesium lost during urination. Lastly, calcium is added to improve hydration.
Stevia, while one of the safer sweeteners, has recently been found to alter the gut microbiome,[3] potentially adversely affecting metabolism.
The recommended drinking target is every three days if not sexually active; if sexually active, every three days and immediately after sexual intercourse. You can take a Flush packet daily and mix one packet in 8 ounces-12 ounces of water for maximum support.
Defend

A cleanse for biofilm that also helps support bladder wall health, a daily defense for improved urinary flow.
- Manage microorganisms in the bladder.
- Natural ingredients.
- Cleans biofilm in the bladder
- Not vegan capsules.
Defend has two main functions, to help cleanse biofilm and to maintain the bladder.
Biofilm is a group of microorganisms bound together that attach to the bladder wall, the natural barrier that helps keep harmful bacteria at bay.
Ingredients in Defend are black pepper powder to improve the absorption of curcumin. With 95% curcuminoids, turmeric root extract can help manage the biofilm. Black pepper powder and turmeric root extract are generally recognized as safe by the FDA.
D-mannose and green tea extract help flush out microorganisms in the bladder.
Vitamin D3 helps increase tight junction proteins found in the bladder. As vitamin D is a fat-soluble vitamin, an excess can cause toxicity.
The tolerable upper intake[4] level of vitamin D for adults is 4000 international units; in Defend, you will find 1500 IU. Vitamin D is the only ingredient not vegan, sourced from sheep’s wool.
The recommended dosage is two capsules daily, with water.
Promote

It helps keep the vaginal microbiome in balance, improving the overall health of the vagina and, therefore, a healthy urinary tract.
- Probiotics for vaginal health.
- Antibiotic-free.
- Natural ingredients.
- Not intended for men.
Promote is the third part of the proactive regimen; it’s recommended for women that are going through menopause or are sexually active. These are probiotics for the vagina, and Uqora indicates that research has shown that vaginal health[5] is linked to urinary tract health.
This dietary supplement only contains the probiotic blends; lactobacillus acidophilus, lactobacillus rhamnosus, and lactobacillus reuteri. Promote is not a digestive probiotic and indirectly helps with UTI prevention.
The recommended dosage is to take one capsule per day with water.
Who Should Take Uqora?
Uqora’s products are meant as preventative care for people who struggle with acute urinary tract infections or recurrent urinary tract infections.
The three-part proactive regimen is meant for women, mainly because the third product Promote is probiotics meant for vaginal health.
Uqora products are safe for women that use contraceptives and won’t impact contraceptive effects.
Men can also benefit from Flush and Defend products.
Uqora products Flush, Defend, and Promote have also been demonstrated for safety and efficacy in children under the age of 12. In this case, speak to your child’s pediatrician before starting any dietary supplement.
The Uqora product Flush can be used by children older than four who weigh at least 45 pounds.
The dosage for Defend recommends one capsule for children over four years old due to the vitamin D in the supplement.
Who Should Avoid It?
Uqora products are not recommended for people who use indwelling catheters but can be used by external catheter users.
If you have health conditions like diabetes, you should first consult with your physician. Flush and Defend both contain D-mannose, a carbohydrate that may not spike sugar levels in the blood of a healthy person but may affect a person with diabetes.
Also, Flush contains vitamin C, which may affect blood glucose monitors and may report false sugar spikes in the blood.
Anyone taking antibiotics should avoid using Flush drink mix due to its potassium and potassium citrate content but can take Defend and Promote safely.
What Do We Like About Uqora?
Regimen
The three-part regimen of Uqora’s products is meant to be proactive, to provide the body with high-quality ingredients commonly found in foods. These ingredients can help diminish recurring infections or for people that experience recurrent UTIs.
Healthy Vagina
Uqora doesn’t just address the urinary system’s health; Uqora focuses on the importance of keeping the vagina’s microbiome in balance.
Promote contains a blend of three probiotics that help with the microbiome that keeps the vagina healthy.
On the Uqora website, you can also find a section on UTI education. It has a learning center with articles written based on medical studies on urinary health.
D-mannose
An active ingredient found in Flush and Defend has been heavily studied for its positive effects in managing the bacteria responsible for the development of existing biofilm in the bladder wall, bladder infections, and urinary tract infections.
A recent 2022 study[6] reviewed various clinical trials, and the overall results were that all studies had reported that D-mannose helped urinary tract infection symptoms decrease.
It’s also common for individuals to develop cystitis, a bladder inflammation. The bacteria responsible for the inflamed bladder that could lead to bladder infections is E. coli bacteria.
D-mannose has similar receptors that are exposed by the cells in the bladder, and when D-mannose is present in the urine, E. coli attaches to it and is excreted.
Uqora Offers
Each Uqora product has promising support for a healthy urinary system, but the retail prices can be steep. Fortunately, you can save money by subscribing to get deliveries every four weeks, with no discount code needed.
Alternatives To Uqora

Hum Nutrition
- Probiotics and cranberry supplements in one capsule.
- Third-party tested.
- No artificial colors, sweeteners, or preservatives.
- Formulated by RDNs.
- Probiotics are not for men.

Hello Wisp
- The doctor prescribed UTI antibiotics.
- Over-the-counter options.
- Subscribe and Save.
- D-mannose and probiotics are sold separately.

Love Wellness
- Contains eight probiotics.
- Natural ingredients.
- One billion CFUs per serving.
- Free of artificial dyes, flavors, or sweeteners.
- Not vegan.
What Customers Say
Most customers of Uqora vary in age groups, and many have positive reviews stating the products are an effective treatment to help prevent UTIs. But some other clients searching for preventing UTIs have instead encountered some side effects or have not found the relief they were searching for.
So thankful for this product
I started Uqora about 3 months ago after I was getting monthly UTIs. I noticed an immediate difference and thankfully no UTIs. This product was specifically recommended to my by my Uro-gynecologist. It’s a lifesaver!
Karen S.
What a relief
I was starting to get UTIs about every 2-3 months when I haven’t had one in over 20+ years. This is giving me a piece of mind. I showed my doctor the website and she was very impressed and encouraged me to try it.
Christine W.
UTI free one year..YAY !!!
After frequent UTI’s..and last year had UTI in January.February and March..said enough..Started taking Promote everyday.. and d-mannose powder at night..and shower after every BM..sorry to be so descriptive but as a nurse.it’s my nature..I move my bowels in the A.M. and immediately shower..and use Uquora Wash Balancing Vulva Cleanser..Do I know exactly what has helped..no..but I do know that my last UTI was MARCH 15..2022..I celebrated this year.. one year UTI free !I! ..will not change my routine since must be doing something right.
Jeanne N.
I’m not knocking Uqora but, I was hoping that it would help with infections that I get from incontinence and the fact that I go to the restroom a lot but this did nothing for me. Not saying that it was designed for my type of problem, but I was hoping it would help.
Cheryl B.
Didnt Work For Me
I needed a product for better vaginal health because Ive been struggling with recurring BV. Unfortunately this product didnt make a difference in my symptoms. I wanted to try the other products but since this one didnt work, Im not sure I want to spend my money on more products that dont work.
Kitta
Not so great for me
I had horrible diarrhea the day I started these. It continued and for about five days I was going to the bathroom all the time. Until I finally stopped taking it. I was hoping for less UTIs but this was not a good experience.
Kara K.
Side Effects Of Using Uqora
Trying to control and promote a healthy urinary system can lead to trying out a variety of supplements. But like any product, not all products are for everyone.
The Uqora product brand has good reviews, but there is one report of gastrointestinal issues like severe diarrhea.
Peer-reviewed studies of D-mannose indicate that it can be protective against recurrent UTIs[7] and found that a small group of people can experience diarrhea. Unfortunately, these peer-reviewed studies were of older studies, and the side effect of diarrhea may have changed since those studies were made.
One other mentioned side effect by a reviewer was breakouts.
Due to Defend’s vitamin D3 ingredient, there is a possibility of toxicity if excess vitamin D is consumed through other dietary supplements.
Final Thought: Is Uqora Worth Trying?
Uqora products mainly target UTI prevention, with its three-part proactive regimen that can help target and control symptoms before they occur.
Because the Uqora target is UTI prevention, some of the additional benefits are the focus on education and a product that provides a variety of high-quality ingredients that can also be found in foods.
Uqora also has other products to help manage symptoms of a urinary infection while you wait to see a doctor. The Uqora website is also a good place for education on managing infections and steps to keep the urinary system healthy.
Like any dietary supplement, it’s recommended to first consult your physician before starting any new supplement.
Frequently Asked Questions
Uqora is made in consultation with health professionals, like urologists and scientists. Each physician may have their own opinion and would need to base a decision according to their own health goals.
It is meant to help the immune system reduce instances of urinary infections.
It depends on the supplement; in the proactive regimen, there are three dietary supplements, each with a blend of nutrients unique to each bottle.
It’s possible to manage symptoms by drinking lots of water and using cranberry juice or pills. But this is not guaranteed to get rid of urinary infections.
Men can use Flush and Defend to control and promote a healthy urinary system.
+ 7 sources
Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here
- Oghenekome Gbinigie, Spencer, E.A., Heneghan, C., Joseph H.W. Lee and Butler, C.C. (2020). Cranberry Extract for Symptoms of Acute, Uncomplicated Urinary Tract Infection: A Systematic Review. Antibiotics, [online] 10(1), pp.12–12. doi:https://doi.org/10.3390/antibiotics10010012.
- Ecfr.gov. (2023). eCFR :: 21 CFR Part 184 — Direct Food Substances Affirmed as Generally Recognized as Safe. [online] Available at: https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-184.
- Konstantinos Rizas, Sams, L.E. and Steffen Massberg (2023). Non-nutritional sweeteners and cardiovascular risk. Nature Medicine, [online] 29(3), pp.539–540. doi:https://doi.org/10.1038/s41591-023-02245-3.
- Nih.gov. (2015). Office of Dietary Supplements – Vitamin D. [online] Available at: https://ods.od.nih.gov/factsheets/Vitamind-HealthProfessional/#h8.
- Microbiology Spectrum. (2016). The Vaginal Microbiota and Urinary Tract Infection | Microbiology Spectrum. [online] Available at: https://journals.asm.org/doi/10.1128/microbiolspec.UTI-0025-2016.
- Fabio Parazzini, Ricci, E., Fedele, F., Chiaffarino, F., Esposito, G. and Cipriani, S. (2022). Systematic review of the effect of D‑mannose with or without other drugs in the treatment of symptoms of urinary tract infections/cystitis (Review). Biomedical Reports, [online] 17(2). doi:https://doi.org/10.3892/br.2022.1552.
- Lenger, S.M., Bradley, M.S., Thomas, D., Bertolet, M., Lowder, J.L. and Sutcliffe, S. (2020). D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology, [online] 223(2), pp.265.e1–265.e13. doi:https://doi.org/10.1016/j.ajog.2020.05.048.