03:43pm Sunday 17 December 2017

Interleukin-27: Can a Cytokine with Both Pro- and Anti-Inflammatory Activity Make a Good Drug Target?

The article is available free on the JICR website until November 20, 2014.

Christopher Wynick, Carlene Petes, and Katrina Gee, Queen’s University, Kingston, Canada, explain how IL-27 can contribute to the control of both anti- and proinflammatory responses depending on the predominant type of immune response elicited in the body, the disease type, and the disease severity. They focus primarily on the proinflammatory activity of the cytokine in the article “Interleukin-27 Mediates Inflammation During Chronic Disease.”

“IL-27 is emerging as a significant determinant of the character of inflammatory response and this review provides an important perspective,” says Co-Editor-in-Chief Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation, Ohio.

About the Journal
Journal of Interferon & Cytokine Research (JICR), led by Co-Editors-in-Chief Ganes C. Sen, PhD, Chairman, Department of Molecular Genetics, Cleveland Clinic Foundation, and Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation, is an authoritative peer-reviewed journal published monthly online with Open Access options and in print that covers all aspects of interferons and cytokines from basic science to clinical applications. JICR is an official journal of the International Cytokine & Interferon Society. Complete tables of content and a sample issue may be viewed on the Journal of Interferon & Cytokine Research website.

About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Viral Immunology, AIDS Research and Human Retroviruses, and DNA and Cell Biology. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry’s most widely read publication worldwide. A complete list of the firm’s 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.


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