In the hunt for new antibiotics, also our own barriers to infections are becoming exploited. It seems apparent that if pathogens become resistant to our natural defense systems, the consequences may be much worse than if resistance develops against an antibiotic originating from, for example, soil bacteria or fungi. Regulatory frameworks have completely missed this risk. This calls for action both on the regulatory and the research side, argues Joakim Larsson, director of CARe in an article published in the International Journal of Antimicrobial Agents this week.
Reference to the study:
Larsson DGJ. (2018). Risks of using the natural defense of commensal bacteria as antibiotics call for research and regulation. Int J Antimicrob Agents. https://doi.org/10.1016/j.ijantimicag.2017.12.018