Scientists have begun the first human clinical trial of EDP-788, an investigational oral antibiotic intended to treat methicillin-resistant Staphylococcus aureus (MRSA) infections. The Phase 1 trial, which will enroll as many as 64 healthy men and women ages 18 to 45, will evaluate the investigational drug’s safety as well as how it is broken down and processed in the body. The trial is being conducted by the Massachusetts-based biotechnology company Enanta Pharmaceuticals through contract funding from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. NIAID funded Enanta’s earlier preclinical testing and development of EDP-788.
Information about this clinical trial is available at ClinicalTrials.gov using the identifier NCT01999725.
NIAID Director Anthony S. Fauci, M.D.; Helen F. Schiltz, M.S., Ph.D., program officer in the Drug Development Section of NIAID’s Office of Biodefense, Research Resources and Translational Research; and Gregory A. Deye, M.D., medical officer in NIAID’s Division of Microbiology and Infectious Diseases, are available to discuss the clinical trial.
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NIAID conducts and supports research—at NIH, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at www.niaid.nih.gov.
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