To guarantee the absence of these bacteria, it is necessary to block batches for 24 to 48 hours before they are put on the market, which can be a handicap. After first developing a method to count bacteria of interest, scientists in the Laboratoire de Chimie Bactérienne (CNRS/Aix-Marseille Université), the Institut de Chimie des Substances Naturelles (CNRS) and the Institut de Chimie Moléculaire et des Matériaux in Orsay (CNRS/Université Paris-Sud) are now proposing a new technique to rapidly detect and concentrate cultivable Gram-negative bacteria1. This innovative process, which will enable the release of commercial batches within a day and be exploited by the start-up company Click4Tag, is described in PLOS ONE on 10 June 2015.
1 The term ‘culturable bacteria” refers to live bacteria that are capable of development. Their presence in a sample may be dangerous. Pathogens such as Escherichia coli or Salmonella typhimurium are Gram-negative bacteria.
Rapid and specific enrichment of culturable Gram negative bacteria using non-lethal copper-free click chemistry coupled with magnetic beads separation ; Emilie Fugier, Audrey Dumont, Annie Malleron, Enora Poquet, Jordi Mas Pons, Aurélie Baron, Boris Vauzeilles, Sam Dukan ; PLOS ONE ; 10 June 2015.
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