The PrELUDE Study (NSW PrEP Demonstration Project) is the largest study of its kind in Australia and will enrol 300 people with a focus on people at heightened risk of acquiring HIV.
“Several important clinical trials have established that PrEP is an effective HIV prevention strategy for both gay men and heterosexuals,” said Dr Iryna Zablotska-Manos, chief investigator of the study at the Kirby Institute. “But whether PrEP confers high rates of protection in real life situations and is a feasible strategy to implement still requires further investigation, and that is what we are seeking to do through PrELUDE.”
To date, TRUVADA® is the only antiretroviral medication that has been approved by the US Food and Drug Administration (FDA) for preventative use as PrEP among individuals at high risk for HIV. Although it is currently not licensed for this purpose in Australia, the NSW Government is committed through the NSW HIV Strategy 2012-2015 to considering how to most appropriately and efficiently implement PrEP as part of a combination approach to the prevention of HIV transmission.
Initially, the study will recruit participants in four large HIV and sexual health services in NSW which currently provide ARVs as treatment and as non-occupational post-exposure prophylaxis of HIV. These will include:
- Royal Prince Alfred Sexual Health (RPASH)
- St. Vincent’s Hospital (SVH)
- Sydney Sexual Health Centre (SSHC)
- Western Sydney Sexual Health Clinic
As recruitment evolves, other health providers in NSW will be engaged.
Media contact: Laurie Legere, +61 413 476 647