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Best HGH Supplements 2022: 4 Human Growth Hormone Boosters

Lisandra Fields

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Medically reviewed by Kathy Shattler, MS, RDN

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CrazyBulk HGH-X2 best HGH supplements

CrazyBulk HGH-X2

  • Doubles as an anti-viral for individuals with cystic fibrosis 
  • Aids in hepatitis treatment
  • Helps stimulate the pituitary gland

GenF20 Plus best HGH supplements

GenF20 Plus

  • Diminishes fine lines, wrinkles, and other age-related facial blemishes
  • Enhances emotional focus
  • Maximizes exercise efficiency

HyperGH 14X best HGH supplements

HyperGH 14X

  • Contains L-arginine, a powerful amino acid that triples HGH levels.
  • Replaces soft body fat with lean muscle mass
  • Offers faster and smoother recovery times

In the past few years, human growth hormone supplements have experienced an unprecedented surge in popularity. They’re primarily used by bodybuilders and anyone looking to shed some weight and improve muscle mass.

If you’re looking to boost your natural human growth hormone levels, you’re in the right place. This post will let you in on some of the best human growth hormone (HGH) supplements on the market and break them down in a detailed and straightforward manner. Keep reading to find out their ingredients, benefits, downsides, and basically everything there is to know about them. Let’s get into it, shall we?

Best HGH Supplements in (December. 2022)

What Is Human Growth Hormone?

The pituitary gland is responsible for the production of the human growth hormone (HGH). This hormone is responsible for regulating body composition and helping children/adolescents develop bone strength, lean muscle mass, and body fluids. The more you grow, the slower the production of the growth hormone. That’s where HGH supplements come in. They have even been proposed to provide anti-aging benefits[1] and to stimulate the immune system.

Try taking HGH supplements if you think you’re experiencing a drop in your growth hormone levels. These products will allow you to experience bigger and better gains in the gym, among other health benefits. They work with your pituitary gland to stimulate the secretion of more natural growth hormone levels.

Is It Good To Use?

Most natural HGH formulas are packed with healthy HGH releasers such as vitamins, proteins, and amino acids and are completely safe to use. Taking HGH supplements can help you build your own levels of human growth hormone up. However, using an HGH formula without recommendation by a clinical health professional could result in preventable side effects.

Is HGH Releaser Better than Synthetic HGH Injections?

Synthetic injections treat a plethora of medical conditions including short-bowel syndrome, Turner’s syndrome, short-stature, and Prader-Willis syndrome. Supplementation without synthetic HGH injections is possible in non-medical conditions. Human growth hormone releasers are sold via pill and vapor sprays but the injections are the only sure way[2] to increase the levels of human growth hormones in the body.

Human growth hormone supplement reviews are rather contradictory. One such review[3] stated that a personal trial with human growth hormone supplements promoted better sleep, and this user’s body became leaner, stronger, and bigger. Whether human growth hormone supplements work to stimulate the pituitary gland’s HCG production seems to vary by user and more research needs to be done.

The Line Up At A Glance

CrazyBulk HGH-X2

Best Overall

CrazyBulk HGH-X2

  • Doubles as an anti-viral for individuals with cystic fibrosis 
  • Aids in hepatitis treatment
  • Helps stimulate the pituitary gland

GenF20 Plus

Best For Anti-Aging

GenF20 Plus

  • Highly concentrated lab-grade CBD 
  • Full-spectrum CBD oil tinctures
  • Save 15% with recurring subscription

HyperGH 14X

Best For Muscle Building

HyperGH 14X

  • Contains L-arginine, a powerful amino acid that triples HGH levels.
  • Replaces soft body fat with lean muscle mass
  • Offers faster and smoother recovery times


Best For Testosterone Increase


  • Tackles unbearable effects of Andropause
  • Improves overall appearance and health
  • Enhances sex drive and physical stamina

4 Best HGH Supplements For Muscle Building 2022

CrazyBulk HGH-X2

HGH-X is a natural supplement that helps increase your body’s HGH naturally.

  • 100% natural ingredients
  • Accelerates recovery period
  • Helps in the fat-burning process
  • Might bring about excessive muscle gains

HGH-X2 from CrazyBulk is ideal for health-conscious individuals who want to utilize a perfectly legal product with zero side effects and not rely on prescription HGH injections. HGH-X helps build muscle, reduce fat, boost energy levels, and offers anti-aging benefits.

HGH-X2 offers similar benefits to Somatropin (HGH injections that are illegal to take without prescription), except it’s perfectly legal and safe. It contains unique ingredients such as the Velvet Bean (scientifically known as Mucuna Pruriens), Hawthorn Berry Extract, and the Maca root that aid in the muscle-building process. It is, essentially, the natural alternative to injections.

The Velvet Bean helps with virility, owing to its dopamine content. Hawthorn Berry Extract helps treat heart issues, while Maca root enables you to adapt to new stressors and regimens. Each ingredient is safe and offers zero side effects. 

CrazyBulk HGH-X2  is available for purchase on their official website and comes with a money-back guarantee.

GenF20 Plus

GenF20 Plus is an HGH formula that comes in the form of a pill.

  • Promote better sleep
  • Decreases fat mass
  • Helps boost HGH levels
  • Some users report feeling anxious or jittery after use

GenF20 Plus is an HGH formula that comes in the form of a pill. It’s made with all-natural ingredients that boost muscle growth, reduce fat, and improve energy levels. GenF20 Plus also helps promote better sleep and improved overall health.

Other ingredients such as Colostrum, L-Ornithine, and Chromium help. carry out its functions effectively to ensure low body fat levels, slowed aging, and production of consistent HGH production.

HyperGH 14X

This advanced supplement utilizes advanced mechanisms that work with the pituitary gland to boost muscle growth while preventing the effects of aging

  • Better and longer erections
  • Faster muscle gains
  • Great for shredding and bulking
  • Takes a while before results become visible (up to 6 months)

This advanced supplement utilizes advanced mechanisms that work with the pituitary gland to boost muscle growth while preventing the effects of aging. Some of these ingredients include the Astragalus Root and Tribulus Terrestris. They’re quite unique and come with multiple health benefits such as boosting production of HGH, faster recovery periods after workouts, enhanced physique, better results from exercise, etc.

HyperGH 14X comes in oral tablets that should be taken twice every day for best results. Take the first dose in the morning to ensure you get the right amount of stamina and energy as you exercise. Take the second dose before bed to optimize HGH production as you sleep.


Provacyl is one of the top HGH supplements designed to help increase HGH and testosterone levels in the body. 

  • Contain D-Aspartic Acid that enhances testosterone levels
  • Optimizes the mind and body
  • Highly beneficial to your sex drive
  • The D-Aspartic Acid content makes it exclusively ideal for men 
  • Available only on the official website

Provacyl contains ingredients such as L-Tyrosine, L-Lysine, Longjack, Magnesium, L-glycine, Ginseng, Swedish flower pollen, essential vitamins (B6, K2, D3), among others. It’s basically a combination of vitamins, nutrients, and amino acids that work together to fight andropause[4](male menopause) and boost testosterone levels. 

This effective and easy-to-use formula also lowers the rate of aging and improves mental clarity.  

Provacyl also includes antioxidants and other essential nutrients for healthy hormone production. It contains ingredients like GABA, which increases HGH naturally.

Final Judgement

From the list above, it’s apparent that one of the best HGH supplements on the market is HGH-X2 by CrazyBulk. The brand itself has a proven track record of beneficial formulas and is designed to assist generally anyone with a desire to reshape their physical structure.

HyperGH 14X comes in oral tablets that should be taken twice every day for best results. Take the first dose in the morning to ensure you get the right amount of stamina and energy as you exercise. Take the second dose before bed to optimize HGH production as you sleep.

HGH-X is a natural growth hormone releaser that helps build muscle faster than other supplements. It contains an all-natural formula of amino acids and herbs that increase your body’s production of HGH. When used in conjunction with a healthy diet and regular exercise, HGH-X can help you reach your fitness goals much faster than you ever thought possible.

One of the main benefits of using CrazyBulk HGH-X is that it can help you achieve a significant increase in muscle mass. This is because it helps to promote protein synthesis and nitrogen retention, both of which are essential for muscle growth.

If you’re looking for a safe, all-natural way to boost your growth hormone levels and build muscle faster, then CrazyBulk HGH-X is the supplement for you! Not only does it work incredibly well, but it also comes with a 100% money-back guarantee, so there’s absolutely no risk involved.

Common Ingredients In HGH Supplements

Some of the best HGH supplements contain ingredients such as deer antler velvet, L-arginine, GABA, Ginseng, Glutamine, Maca root, and Growth Hormone Releasing Peptide-six (GHRP-six). Each of these ingredients has been shown to have various benefits for muscle growth and development. Let’s take a closer look at each one.


One of the most crucial amino acids for bodybuilders is glutamine. It helps preserve muscle mass as you cut calories, which can be crucial when trying to lose weight. Glutamine is also known for its ability to increase growth hormones. In fact, one study[5] showed that supplementing with glutamine increased HGH levels by more than 400%.

This is why many HGH booster supplements include it as one of their ingredients. Glutamine plays a vital role in protein synthesis[6], which is the process by which muscles grow and repair. It also helps reduce muscle soreness and fatigue, making it an essential part of any supplement regimen to build muscle mass.

Glutamine promotes muscle growth and supports the immune system. A recent study[7] looked at the effects of glutamine on young athletes who were undergoing intense training. The results showed that those supplemented with glutamine had less muscle soreness and better overall health than those who did not supplement it.

While more research is needed to determine the effects of glutamine on muscle growth and HGH levels, this study provides some evidence that it may be a beneficial ingredient in an HGH supplement. If you’re looking for a product containing glutamine, make sure to do your research to find one that has been tested and proven effective.

Glutamine has been shown to increase HGH levels when taken before bed. Natural growth hormone is released primarily during sleep. So if you’re looking for an effective HGH supplement, be sure to look for one that contains glutamine.

Deer Antler Velvet

Deer antler velvet is perhaps the most popular ingredient in HGH supplements. This ingredient is derived from the soft tissues that cover deer antlers. It is rich in nutrients like protein, collagen, and minerals like zinc, magnesium, and iron. Deer antler velvet has been shown to promote muscle growth and strength gains and increase endurance levels[8].


L-arginine is an amino acid that is found in any modern and natural HGH supplement. It is said to play a role in muscle growth and recovery, although there is limited evidence[9] to support this claim. L-arginine may also help improve blood flow and circulation.

L-arginine is an amino acid that plays a key role in the production of nitric oxide. Nitric oxide is a compound that helps dilate blood vessels, allowing more blood and oxygen to reach your muscles. This can help to improve muscle growth and strength.


GABA (gamma-aminobutyric acid) is a neurotransmitter that helps to regulate mood and stress levels. It has also been shown to promote muscle growth and fat loss. GABA can help keep you calm and focused during your workouts, leading to better results. This compound has been added to some HGH supplements, even though there is no evidence that it actually increases HGH levels. In fact, some experts believe that GABA may actually have the opposite effect and suppress HGH production[10].


GHRP-six is a peptide that helps to stimulate the release of growth hormones. Growth hormone plays a key role in muscle growth and development. GHRP-six has been shown[11] to increase muscle mass, strength, and endurance and reduce fat mass.

Maca Root

The maca root is a Peruvian plant that has been used for centuries as a natural way to boost energy, fertility, and libido[12]. It is also thought to help with anxiety and depression. 

Some of the benefits of maca root include: Increased energy levels, increased libido, improved fertility, reduced anxiety and depression symptoms, better overall mood, increased muscle mass, and faster recovery times after workouts.

These are some of the most common ingredients found in HGH supplements. Each of these ingredients has been shown to have various benefits for muscle growth and development. If you’re looking for a supplement that can help you achieve your fitness goals, then consider one that contains any or all of these ingredients.

Potential Side Effects

Although human growth hormone supplements can be effective for muscle growth, they also come with a few potential side effects. Some of the most common side effects include:

  • Joint pain
  • Muscle aches
  • Nausea
  • Headaches
  • Dizziness
  • Heart problems
  • Carpal tunnel syndrome

If you experience any of these side effects, stop taking the supplement and consult your doctor. Additionally, HGH supplements should not be taken by anyone under 18,  pregnant women, or those who are breastfeeding.

So before you start taking an HGH supplement, it’s important to understand the potential risks involved. However, with proper research and caution, HGH supplements can be an effective way to help you reach your muscle-building goals without having to rely on prescription injections.

How To Choose The Best HGH Pills?

There are a lot of different HGH supplements on the market, and it can be difficult to decide which one is right for you. Here are some tips on how to choose the best supplement for your needs:

  • Look for a supplement that contains natural ingredients. Some of the most common natural ingredients found in HGH supplements include deer antler velvet, L-arginine, and glycine.
  • Make sure the supplement is made by a reputable company. Look for a company that has been in business for several years and has a good reputation.
  • Look for a supplement that has been certified by an independent organization like the NSF or USP.
  • Make sure the supplement is backed by a money-back guarantee. This way, if you don’t see results, you can get your money back.
  • Check out customer reviews to get an idea if this particular supplementation is right for you – they could tell of positive or negative experiences while using it so far. 
  • Look for products that have been third-party lab tested for the safety of ingredients and guarantee that the quantities on the label are what is in the bottle.

Once you’ve chosen a good HGH supplement, follow the directions carefully and drink plenty of water. And be patient – it may take a few weeks before you start seeing results.

Human Growth Hormone For Sale

The best HGH supplements are available on the manufacturer’s website. Fake supplements abound and the only way to assure you are getting the real deal is to go to the actual site that sells the name brand supplement. Human growth hormone is considered a controlled substance by the FDA and does not come in pill form. Only supplements can be legally purchased to support lean muscle mass and to stimulate endogenous human growth hormone production.

Final Thought

If you are looking for a safe and effective way to increase your HGH levels, then a supplement may be the right choice for you. Supplements can help you build muscle, lose weight, and improve your overall health. 

Remember to always consult with a doctor before starting any new supplements. And be sure to follow the dosage instructions carefully. Taking too much of any supplement can be dangerous and could lead to adverse effects.

Start by doing your research and finding the right supplement for you. Then, start taking it as directed and see how it works for you. Supplements can be a great way to improve your overall health and fitness level.

Frequently Asked Questions

Are there any side effects associated with growth hormone supplements

Like with any supplement, it’s important to research the potential side effects before taking an HGH supplement. Some of the most common side effects include headaches, nausea, and joint pain. However, these side effects are usually mild and temporary.

What is the most effective HGH supplement?

There is no one-size-fits-all answer to this question, as the most effective HGH supplement will vary from person to person. However, some of the most popular and well-reviewed HGH supplements include GenF20 Plus, HyperGH 14x, and Somatroppine. Do your research before choosing a supplement and consult with a doctor if you have any concerns.

Do HGH supplements really work?

Yes, they do. Some of the key benefits of taking HGH supplements include increased muscle mass, decreased body fat, improved sleep quality, and better overall health. These supplements can also help improve cognitive function and memory.

What supplements increase HGH?

Some of the best HGH supplements include GenF20 Plus, HyperGH 14x, and Somatroppine. It’s important to do your research before choosing a supplement and to consult with a doctor if you have any concerns.

What is the safest HGH to take?

Different HGH supplements can have different effects on different people. However, it’s generally recommended that beginners start with a low dosage and work their way up if needed. It’s also important to do your research before choosing a supplement and to consult with a doctor if you have any concerns.

Should I take HGH supplements if I’m not experiencing any symptoms of low HGH?

There is no right or wrong answer to this question, as everyone’s body reacts differently to supplements. However, it is generally recommended that only people who are experiencing symptoms of low HGH take HGH supplements. If you have any concerns, it’s always best to consult with a doctor.

Are there any other ways to increase my HGH levels?

There are several things you can do to increase your HGH levels naturally, including exercise, getting adequate sleep, and reducing stress levels. If you’re looking for a more targeted approach, you can also try using HGH releasers or testosterone boosters. Growth hormones can be obtained through your doctor and include prescription HGH injections.

What is the best time of day to take an HGH supplement?

There is no right or wrong answer to this question, as different people react differently to supplements. . To maximize effects, it has generally been recommended to take HGH releasers 30 minutes before bedtime to work with the body’s natural rhythm of producing the hormone at night.

+ 12 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Colon, G., Saccon, T., Schneider, A., Cavalcante, M.B., Huffman, D.M., Berryman, D., List, E., Ikeno, Y., Musi, N., Bartke, A., Kopchick, J., Kirkland, J.L., Tchkonia, T. and Masternak, M.M. (2019). The enigmatic role of growth hormone in age-related diseases, cognition, and longevity. GeroScience, [online] 41(6), pp.759–774. Available at: https://link.springer.com/article/10.1007/s11357-019-00096-w.
  2. MetroMD. (2015). MetroMD. [online] Available at: https://www.metro-md.com/do-hgh-supplements-actually-work/.
  3. MaleHealthReview. (2019). HyperGH 14X – The Real Deal or Hyper BS? You Won’t BELIEVE It! [online] Male Health Review. Available at: https://malehealthreview.com/hypergh-14x-review.
  4. Mousavi, M., Mahmoudi, M., Golitaleb, M., Khajehgoodari, M., Hekmatpou, D. and Vakilian, P. (2018). Exploratory Study of Andropause Syndrome in 40-65 Years in Arak: A Cross Sectional Study. Journal of family & reproductive health, [online] 12(3), pp.142–147. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571447/.
  5. Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R. and Newsholme, P. (2018). Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients, [online] 10(11), p.1564. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266414/.
  6. Lambertucci, A.C., Lambertucci, R.H., Hirabara, S.M., Curi, R., Moriscot, A.S., Alba-Loureiro, T.C., Guimarães-Ferreira, L., Levada-Pires, A.C., Vasconcelos, D.A.A., Sellitti, D.F. and Pithon-Curi, T.C. (2012). Glutamine Supplementation Stimulates Protein-Synthetic and Inhibits Protein-Degradative Signaling Pathways in Skeletal Muscle of Diabetic Rats. PLoS ONE, [online] 7(12), p.e50390. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519752/.
  7. ZIAEI V, AKBARNEZHAD A, KORDI R, AHMADINEZHAD Z, RAVASI A.A and MANSOURNIA M.A (2008). The Effects Of Weight Loss And Glutamine-Creatine Supplementation On Peripheral White Blood Cells In Elite Athletes. Www.sid.ir, [online] 10(3), pp.191–199. Available at: https://www.sid.ir/en/journal/ViewPaper.aspx?ID=140838.
  8. Chen, J.-C., Hsiang, C.-Y., Lin, Y.-C. and Ho, T.-Y. (2014). Deer Antler Extract Improves Fatigue Effect through Altering the Expression of Genes Related to Muscle Strength in Skeletal Muscle of Mice. Evidence-Based Complementary and Alternative Medicine, [online] 2014, pp.1–10. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950920/.
  9. McRae, M.P. (2016). Therapeutic Benefits of l-Arginine: An Umbrella Review of Meta-analyses. Journal of Chiropractic Medicine, [online] 15(3), pp.184–189. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021928/.
  11. Thomas, A., Kohler, M., Mester, J. and Thevis, M. (2010). Identification of the growth-hormone-releasing peptide-2 (GHRP-2) in a nutritional supplement. [online] ResearchGate. Available at: https://www.researchgate.net/publication/46580988_Identification_of_the_growth-hormone-releasing_peptide-2_GHRP-2_in_a_nutritional_supplement.
  12. Shin, B.-C., Lee, M.S., Yang, E.J., Lim, H.-S. and Ernst, E. (2010). Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complementary and Alternative Medicine, [online] 10(1). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928177/.
Lisandra Fields

Medically reviewed by:

Kathy Shattler

Lisandra Fields is a freelance medical writer from Pennsylvania who creates articles, blog posts, fact sheets, and website content for health-related organizations across North America. She has experience working with a wide range of clients, from health charities to businesses to media outlets. She has experience writing about cancer, diabetes, ALS, cannabis, personality psychology, and COVID-19, among many other topics. Lisandra enjoys reading scientific journal articles and finding creative ways to distill the ideas for a general audience.

Medically reviewed by:

Kathy Shattler

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