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7 Best Supplements For Muscle Growth & Bodybuilding 2023

Mitchelle Morgan

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

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TestoPrime best muscle building supplements


  • Natural ingredients
  • 100% return on unopened capsules
  • Potent testosterone (T) booster

CrazyBulk D-Bal best muscle building supplements

CrazyBulk D-Bal

  • Boosts lean muscle formation
  • Minimal side effects
  • Money-back guarantee

PhenQ best muscle building supplements


  • Vegetarian, all-natural formula
  • Reputable brand
  • Money-back guarantee

Up To 50% Off When Buying In Bulk

There are many different types of dietary supplements available on the market. Some are designed exclusively for weight loss, others for muscle gain, others for relief of fatigue, and still others promise to do it all.

It’s no surprise, then, to come across unique supplements claiming to be the best supplements for building muscle after 60, 50, or even 30.

However, are they effective as they promise to be?

We’ll go over seven of the best muscle-building supplements available in this post. We’ll look at what they are, what ingredients they contain, a little about the brand, and more. So keep reading to find out more about all of these things.

Best Muscle Building Supplements On The Market In (May. 2023)

Do Pills Help Build Muscle & Grow Strength?

The answer to whether muscle-building supplements aid healthy muscle growth is yes, but only if the factors necessary for the supplement to work are present. These include your overall health and your food and lifestyle habits. You should be assessed by a physician and a dietitian, who are the only people who can give you the green light.

Even so, if you want to gain muscle mass, you’ll need to take genuine products in the correct dosages for the job. If hunger suppression is your primary goal, for example, don’t utilize muscle-building supplements. In this instance, the pills will not work.

Protein, amino acid, and other supplements contain components that promote muscle development, including growth, recuperation, and maintenance. However, for them to be totally useful, you must be in good health, practice healthy eating habits, and have a regular exercise program. 

7 Best Muscle Building Supplements For Bodybuilding


TestoPrime contains 12 substances that have been clinically proven to promote natural testosterone generation. This is one of the best workout supplements for men who are 30 and above and looking to boost their testosterone levels (T-levels) and build their lean muscle mass.

  • Lifetime 100% return policy on unopened bottles
  • May boost your energy levels
  • Supports protein synthesis
  • May enhance the fat-burning mechanism
  • A pricy option for a few users

As one of the better supplements for building muscle after 60, TestoPrime’s first active ingredient is a naturally-occurring amino acid called D-aspartic acid. It aids in the production of the luteinizing hormone (LH). This hormone increases testosterone creation in the testes’ Leydig cells in males. The pancreas produces LH; however, ingesting D-aspartic acid[1] can boost its synthesis, resulting in higher T levels.

In addition, TestoPrime contains ashwagandha extract, which is the purest form of ashwagandha. This substance has many health benefits, including assisting with weight loss, improving cognitive capacity, and developing muscle strength[2]. Further yet, ashwagandha extracts can help maintain and even improve[3] your current testosterone levels, guaranteeing that they do not decline as you mature.

Another essential element in the TestoPrime composition is black pepper extract, generally known as piperine[4]. This natural chemical can help your body absorb the other nutrients in the TestoPrime solution, ensuring that you get the maximum benefit from them.

The other nine ingredients are as follows:

Having four TestoPrime pills in the morning can give you the right amount of the formula’s elements to pump your system with testosterone.

CrazyBulk D-Bal

CrazyBulk D-Bal achieves commendable muscle-gaining results by establishing the ideal anabolic environment in your system.

  • Promotes the development of lean muscle mass
  • Has no reported adverse side effects
  • Money-back guarantee
  • Free-shipping
  • Legal to purchase and widely available
  • Some people may consider the price to be excessive
  • Exclusively accessible on the official website

CrazyBulk D-Bal’s foremost function is to boost protein synthesis[11] in your system. This process allows your muscles to get stronger by repairing muscle fibers after exercise. As a result, the supplement stimulates protein synthesis, resulting in faster muscle gains and more visible muscle growth.

Second, CrazyBulk D-Bal can help you increase your insulin-like growth factor (IGF-1[12]) and testosterone levels, two essential hormones that help you grow muscle. The levels of these hormones gradually decrease as people get older. On the other hand, taking CrazyBulk D-Bal can help you regain muscle mass and improve your workout performance by restoring your hormones to their original elevated amounts.

Finally, this muscle-building substance can lower serotonin levels in the brain, reducing fatigue[13]. This muscle-building supplement can boost your adenosine triphosphate, ATP[14], levels at the same time. This chemical accumulates and transports energy in your muscle tissue. Increasing ATP levels can provide you with the stamina you need to finish high-intensity workouts.

The natural constituents in CrazyBulk D-Bal are as follows:



Up To 50% Off When Buying In Bulk

See PhenQ Reviews

The PhenQ weight loss formula advocates that the body’s metabolism may be supercharged to trigger thermogenesis, which is a process that burns calories.

  • Outstanding reputation
  • No synthetic additives added
  • Vegetarian
  • 60-day money-back guarantee
  • Discount on bulk orders
  • Available globally
  • Some people believe it to be prohibitively pricey
  • The results are subject to change from person to person

Thermogenesis allows the human body to burn fat in a manner comparable to that of an exercise. With exercise, results are faster.

Additionally, your body must cease generating and accumulating new fat before it can begin to lose the fat that already exists and build muscle mass. PhenQ may be able to assist you with this.

It does this by releasing a tiny proportion of enzymes that prevent fat storage.

Instead of instructing your body to store carbs as fat, it teaches it to transform them into helpful body energy, accelerating your metabolism. PhenQ enhances the rate at which your metabolism operates, causing your body to burn more calories than ever before. In that same way, your muscles fibers get to form faster since your metabolism rate is high.

This thermogenic environment created fosters an ecosystem in which the body can grow muscular mass.

Here is a list of all the ingredients used in PhenQ:


The product was created to raise T-levels which is vital to maintain muscle mass. The manufacturers claim that this muscle-building supplement is a scientifically proven and all-natural formula.

  • May increase the production of natural testosterone
  • Aids muscle growth and strength
  • Enhances libido, vitality, and mood
  • Ingredients are all-natural, high-quality, and well-researched
  • Safe and transparent
  • Only available on the official website
  • This product is not vegan-friendly

The manufacturers purport that it can increase muscle mass and endurance, promote weight loss, increase libido, and enhance mood. The supplement contains an anabolic support complex to build muscle and to maintain muscle strength. The most straightforward approach to see the best possible results from this muscle-building supplement, namely muscle development and weight loss, is to take your dosages throughout the day. Swallow one tablet first thing in the morning with breakfast, another one with a mid-morning snack, and one at lunchtime and supper, as advised by the manufacturer.

It also falls into the category of the best supplements for muscle building after age 60.

This all-natural recipe contains the following ingredients:

CrazyBulk Stack

CrazyBulk Stack muscle-building stack contains four distinct supplements: Trenorol, Testo-Max, D-Bal, and DecaDuro. This combination is meant to help you gain mass faster.

  • This package contains four different products
  • May help speed up the process of muscle gain
  • Boosts the metabolism of proteins
  • You need prior experience to use this stack

Trenorol can enable you to preserve nitrogen in your muscle cells and increase blood cell synthesis. Boosting your production of red blood cells can assist your muscles in seeming more polished and visible by giving them a much more venous look. It contains milk products so if you are sensitive to dairy, you will want to avoid this product.

The inclusion of D-aspartic acid in Testo-Max can boost your testosterone levels. This amino acid increases luteinizing hormone generation, which allows your body to create extra testosterone.

D-Bal contains chemicals that aid in the growth and maintenance of muscle mass. This mixture contains ingredients like ashwagandha, which increases lean muscle mass when bulking, and methylsulfonylmethane,( MSM)[22], which reduces muscular soreness.

DecaDuro also promotes muscle development by letting your muscles store more nitrogen, which helps your system to generate more protein. Nitrogen retention also increases the number of O2 red blood cells in the bloodstream, allowing your muscle fibers to receive more oxygen.

Every day, Crazy Bulk suggests having Testo-Max in the morning, Trenorol and DecaDuro before your training, and D-Bal afterward.


PrimeShred is made with an apparent formula free of animal products, soy, dairy, and gluten. It is ideal for both vegans and vegetarians to use this muscle-building supplement.

  • Increase the rate of fat loss
  • It is an energy booster
  • Increase your concentration and mental clarity
  • May assist you in burning more calories to aid in losing weight
  • Company information is hard to find, raising concerns about brand credibility and authenticity

PrimeShred is also backed by a 100-day, no-questions-asked money-back guarantee. You can return any unopened capsules for a complete refund, minus shipping expenses, within 100 days of purchase.

It uses a three-pronged strategy to fat loss that can help your body’s natural fat-burning systems work more efficiently.

It can speed up your body’s natural calorie and fat-burning processes. The formula achieves this effect by accelerating your metabolic rate through thermogenesis.

It can also help you burn fat by activating fat-burning hormones in your body. Finally, this muscle-building supplement formula might help you feel more physically and mentally energized. This formula includes nootropics, which can help you stay engaged on your weight-loss and muscle gaining objectives and minimize brain fog. Nootropics are a class of substances that improve brain health, also called “smart drugs.”

It includes the following:

Crazy Nutrition Ultimate CRN-5

This muscle-building supplement is by far the most popular form of Crazy Nutrition Ultimate CRN-5 sells, and it is available in a variety of dosages. The 50-cent per 30-scoop bottle contains 10.2 grams of powder per scoop and provides the user with increased power, stamina, and vigor.

  • Includes five types of creatine
  • The brand has a good reputation
  • Boosts stamina, strength, and endurance
  • Restores strength and hydration post-workout
  • It may be a bit expensive for some users

In light of Crazy Nutrition’s stellar reputation and the fact that CRN-5 includes five kinds of Creatine in high concentrations, it is undoubtedly one of the best creatine supplements available for purchase online.

Crazy Nutrition CRN-5 varies from the other supplements on this list because it contains various kinds of one substance. Five different muscle-building chemicals are combined to make CRN-5, and they are:

CRN-5 also contains other valuable ingredients for the body’s health, such as potassium, sodium[29], and magnesium, which are the three vital components that provide the body with electrolytes. After a strenuous workout, the three chemicals work together to help the body rehydrate and regain strength.

Types Of Muscle-Building Supplements

There are a variety of supplements on the market today that promote muscle tissue growth. Each has its own array of advantages for muscle protein synthesis. The most popular types of these muscle gain supplements are as follows:


This substance used in muscle-building is a non-essential amino acid that can help you perform better in the gym and feel less tired. Beta-alanine occurs at minute levels in your body.

For these reasons, many athletes use beta-alanine supplements to improve muscle endurance and growth. It controls[30] how much of the carnosine molecule can be retained in your tissues. Carnosine decreases[31] muscular acidity, allowing your muscles to work more before becoming exhausted.

When taken in conjunction with weight-lifting, beta-alanine may help to enhance muscular mass, particularly lean body mass.

Branched-Chain Amino Acids (BCAAs)

Branched-Chain Amino Acid supplements can help you build muscle, reduce muscle soreness post-workout, reduce exercise weariness[32], and prevent muscle breakdown. These nutrients are three amino acids that are mainly obtained via diet since our bodies cannot synthesize them naturally.

Casein powder

Casein protein powder is a pleasant, handy, and high-intensity weight-lifting, quickly metabolized milk-based protein supplement.

Casein is broken down slowly, unlike whey protein powder, which causes a substantial jump in blood levels of amino acids shortly after consumption. As a result, it delivers a continuous, steady release of essential amino acids into the bloodstream for a while. This is one of the reasons people consume casein before going to bed to help speed up muscle repair[33].

Creatine Monohydrate

Many workout enthusiasts use creatine, a naturally occurring chemical present in muscle cells, to help them in building muscle mass and enhancing body composition[34]. Creatine monohydrate can also revitalize muscle cells, allowing you to finish more rigorous activities while putting less load on your muscles.

There are numerous types of creatine; however, monohydrate is one of the most powerful and effective. Creatine Monohydrate leads to increased muscle mass, along with a boost in workout performance and muscle strength[35].

Boosters Of Testosterone

Testosterone boosters are dietary supplements that help your body produce more testosterone naturally. Testosterone is important for muscle building[36 and weight loss[37].

If you are above the age of 30 and testosterone production declines with age[38], it may be beneficial to take these boosters to increase testosterone levels in the body.

Whey Protein Supplements

One of the vital amino acids found in dairy products is whey protein. This protein supplement is commonly found in muscle-building dietary products because it has been shown to boost muscle growth when combined with good fitness, a healthy diet, and a weight-lifting routine. Whey protein supplements also include leucine[39], an essential amino acid necessary for muscle protein synthesis[40].

Supplements For Pre-Workout

Pre-workout pills are often made of substances that excite you and increase your exercise stamina, making it simpler to complete intense workouts. Pre-workout supplements can include chemicals that increase nitric oxide production, contributing to faster muscular growth.

There are a variety of combinations that can help you improve your workouts, aid muscle development, lose weight, and help you get into shape fast without using anabolic steroids.

Supplements For After-Workout

People also use post-workout vitamins, which might help them recover faster and avoid muscle breakdown. These post-workout supplements can help you do weight-lifting workouts daily without having to rest your body in between sessions.

Potential Side Effects

 First of all, you will want to purchase authentic and legal dietary supplements for the safety of using the best supplements for muscle growth and body-building. These are the ones that have been regulated by bodies such as the Food and Drugs Administration[41] (FDA) in the U.S. In other countries, bodies such as the Medicines and Healthcare Products Regulatory Agency (MHRA) in the UK monitor the safety of supplements.

These bodies, like the FDA, usually compel the brands to offer a disclaimer on their product which indicates that any claim made has not been evaluated by the FDA. The FDA poses supplement regulations but does not oversee the quality of the finished product or evaluate claims made for the product. Regardless, here are the potential side effects of muscle-building supplements:

  • Aggression due to testosterone production in excess
  • Liver damage
  • Kidney damage
  • Increased blood pressure
  • Heart damage
  • Restlessness
  • Digestive discomforts
  • Irritated skin: flushing, yellowing, rushes
  • Headaches
  • Respiration complications
  • Light-headedness
  • Nausea and vomiting

Take note that these side effects may vary from person to person. However, to avoid all these, you should seek a healthcare provider’s advice to use a supplement to boost muscle growth.

Although if you are already using creatine supplements or a whey protein powder for these same purposes, and you experience any of the above, stop using the product immediately and consult your physician.

Choosing The Best Muscle Building Supplements

Whether your goal is to increase your lean muscle mass or fight muscle fatigue, here are the guidelines you should use to select the best muscle-building supplements.

List Of Ingredients

Ideally, it would be best to go for the best bodybuilding supplements with an ingredient profile of natural ingredients. And even if they have artificial additives, ensure that they are at a minimum. This helps you mitigate any side effects linked to synthetic additives, both short-term and long-term.

Also, consider going for No-Genetically Modified Organisms (GMO) options and building supplements without any allergens, supposing you are allergic to any.

Brand Transparency

It’s is a red flag when a company claims to make the best supplements for muscle gain and withholds the testing and research information about their product. Conversely, go for brands that openly offer you testing and research data on their website or upon request. This way, you are confident that the ingredients you are taking are legit and are in safe dosages.

On that same note, the labeling on the bottle must be clear.

Brand Refund Policy

These should answer what the company making the muscle growth supplements you bought will do; suppose the supplement does not work for you. The refund policy should ideally be fair. For instance, a return policy of 30-days and beyond is reasonable since you have time to use it and determine if the results are as you desire.

Secondly, consider the brand’s conditions for returning the mass-building supplement. Some allow the return of opened products, while others only allow closed packages. But how will you know how it works if it is closed? Unless you just want a refund.

Regardless, a company that allows opened packages makes more sense.

Some companies will pay for shipping, while others will not. Select one that you are comfortable with.

Brand Reputation

On brand reputation, you need to read as many best supplements for muscle growth for men reviews that you can find online before deciding. These reviews will help you decide if you want to make a purchase based on what the product does, what it contains, and how these nutrients work. Reading these reviews gives you first-hand information about how the muscle-building supplement aids in muscle gain, muscle recovery, and eventually effectively promotes your body-building journey.

So much so, read articles on supplements for muscle growth and even go to merchant sites like Amazon and read what actual clients are saying about the product.

Lastly, are there any pending or past warning letters or lawsuits against the brand on brand reputation? Things like FDA-warning letters, recalls, and cancellations should also be on your list of things to prove the credibility of a brand. So ensure you cross-check for these too.

Your Budget

Frankly, the best supplements for muscle growth available have a wide price range. But one thing we can all agree on is that they are not cheap!

That said, you need to set up a long-term budget that you are willing to spend. The reason is that you just do not use one for a month, and that is it. You may have to keep going for at least six months or more to see significant changes.

So can your financial status support its use? If yes, do not hesitate to use any of the seven mentioned above.

Pro-tip: Once you are confident that that brand works for you, consider taking advantage of discounts and stack buying. It would help if you also considered using coupons and purchasing during shopping holidays such as Black Friday.

Final Thought

It’s not a good idea to take someone’s word for it that the supplement they’re using to gain muscle mass is the right one for you. Sure, it may be ideal for them, but it may be the worst experience for you. It would be best to go beyond their advice and conduct some research.

Even so, the first thing you should do is make an appointment with your doctor. The results of your physical examination will help you decide which of the many protein synthesis muscle-building supplements to purchase.

After that, you go ahead and buy it from a merchant you know and trust. However, the quest to gain muscle mass involves different activities such as training. You must maintain healthy habits like eating a well-balanced diet and exercising under supervision for better monitoring. You must also preserve your integrity and consume only the portions you have been instructed to consume. This implies you should never raise the amount of protein in your protein shakes just to gain weight or bulk up faster.

Too much change in the body has consequences. As a result, please stick to the prescribed dosages. That’s how you ensure you’re going to get the best results out of a muscle-building supplement!

Frequently Asked Questions

Which protein is the most effective for muscle growth?

Whey protein supplements are the optimum since they are quick to digest and include branched-chain amino acids (BCAAs). They can aid in the development and maintenance of muscle mass, recovery after intense exercise, and the improvement of muscle strength in response to strength training.

Is it beneficial to utilize supplements when building muscle?

Body-building supplements are an excellent approach to encouraging muscular growth and development. They are used for muscle repair and growth, both of which are essential for your overall body-building program. Protein supplements are beneficial since they supply your body with the necessary amounts of protein.

Is it possible to gain muscle beyond 50?

At 50 or older, it is entirely possible to restore or increase muscle mass. Nutrition and food should be emphasized when trying to gain muscle growth. Ensuring you’re getting the correct quantity of protein is crucial for muscular development.

Is it possible to gain muscle using only supplements?

If your nutrition and training plans aren’t up to par, supplements won’t be able to help you gain the most muscle. It would help if you consumed enough calories and protein to grow muscle along with an exercise program, preferably with weights.

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Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

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Mitchelle Morgan

Medically reviewed by:

Kathy Shattler

Mitchelle Morgan is a health and wellness writer with over 10 years of experience. She holds a Master's in Communication. Her mission is to provide readers with information that helps them live a better lifestyle. All her work is backed by scientific evidence to ensure readers get valuable and actionable content.

Medically reviewed by:

Kathy Shattler

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