Fact checkedExpert's opinion

The article is a subjective view on this topic written by writers specializing in medical writing.
It may reflect on a personal journey surrounding struggles with an illness or medical condition, involve product comparisons, diet considerations, or other health-related opinions.

Although the view is entirely that of the writer, it is based on academic experiences and scientific research they have conducted; it is fact-checked by a team of degreed medical experts, and validated by sources attached to the article.

The numbers in parenthesis (1,2,3) will take you to clickable links to related scientific papers.

Top 7 Best Nitric Oxide Boosters On The Market 2024

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

All articles are produced independently. When you click our links for purchasing products, we earn an affiliate commission. Learn more about how we earn revenue by reading our advertise disclaimer.

Transparent Labs BULK

Transparent Labs BULK

  • Evidence-based ingredients
  • No artificial ingredients
  • Supports lean muscle and testosterone

Jacked Factory N.O. XT Nitric Oxide Booster

N.O. X.T. Jacked Factory

  • Money-back guarantee
  • Affordable
  • Science-backed dosage

Onnit Total Nitric Oxide

Onnit Total Nitric Oxide

  • Helps build muscle
  • Fights fatigue
  • Stimulant-free

Nitric Oxide is becoming more and more popular in the athletic industry. This supplement can speed up muscle growth and blood flow to help those intense muscles pump. Increasing nitric oxide levels will enhance overall workout performance.

Best Nitric Oxide Supplement List (April. 2024)

  • Transparent Labs BULK – Editor’s Choice
  • N.O. X.T. Jacked Factory – Best Nitric Oxide Pills
  • Onnit Total Nitric Oxide– Most Affordable
  • Huge Nutrition Magnify – Most Advanced Formula
  • BlueEarth’s L-Arginine + L-Citrulline – Best Science-Backed Ingredients
  • Snap Nitric Oxide Organic Beets – Best Natural Supplement
  • Huge Pump Serum – Targeted For Men

7 Best Nitric Oxide Supplements Of 2024

Transparent Labs BULK

Nitric oxide boosters can be found in many different supplements. This pre-workout targets lean muscle growth and supports healthy testosterone levels. 

  • Great product reviews
  • Ingredient backed by scientific research
  • Supports lean muscle growth
  • Supports testosterone levels
  • Contains stimulants

Transparent Labs BULK supplement increases nitric oxide within your body through its 19 active ingredients. These ingredients help with muscle pumps, reduce fatigue, decrease muscle soreness, and help you reach peak exercise performance. 

For instance, reports have found[1] that betaine has the potential to increase your body’s nitric oxide production when orally ingested. This is just one of the active ingredients within this effective pre-workout. 

This supplement is designed to be taken before your workout. You should take PreSeries Bulk about twenty-thirty minutes before physical activity with water. It comes in multiple flavors for you to choose from, like watermelon and sour grape. Overall, the reviews for this product are positive, and many users recommend it. 

N.O XT Jacked Factory

One of the best nitric oxide supplements is manufactured right here in the United States. The key benefits of N.O EX nitric oxide booster are increasing nitric oxide production, increased blood flow to muscle tissue, and supporting muscle growth and recovery.

  • Affordable
  • Scientifically-dosed nitric oxide booster
  • Money-back guarantee
  • You have to take three capsules each time

This product promises to be the world’s first scientifically dosed supplement to boost nitric oxide levels. Let’s see if the ingredients back the benefits. This product contains L-citrulline, L-glutathione, Nitrosigine, and Bioperine (black pepper extract). 

Furthermore, evidence[2] has found that nitrosamine helps improve exercise performance by increasing blood flow in the muscles. Reports[3] have also found that L-citrulline improves blood flow during exercise and boosts nitric oxide. The black pepper extract is used to ensure your body absorbs the supplements fully.  It looks like the ingredients in this product back the claims. 

Additionally, this nitric oxide booster supplement comes in capsule form and contains no dyes, fillers, or stimulants. It also has excellent reviews from customers.

Onnit Total Nitric Oxide

Total Nitric Oxide is designed to support your body’s natural nitric oxide production. Its main goal is to promote workout performance to help with fast recovery and muscle growth.

  • Affordable
  • Stimulant free
  • Helps build muscle and fight fatigue
  • Proprietary blends make it hard to know the exact ingredient benefits

These nitric oxide boosters contain fermented beetroot, epiphyte grape seed extract, epiphyte apple extract, acerola cherry extract, L-citrulline DL-malate, arginine nitrate, and Careflow mango fruit powder.  Additionally, it is free from gluten, nuts, and soy. 

However, some studies[4] find that L-arginine does not show a significant increase in nitric oxide levels. In contrast, beetroot juices[5] improve nitric oxide levels, which in turn create more blood flow to muscles. Beetroot juice can also help increase overall workout performance. 

As we mentioned above, L- citrulline is known to help enhance blood flow allowing more muscle pumps. 

This dietary supplement is a powder form. You take one scoop and mix it with at least eight ounces of water up to two times a day. It comes in a harvest fruit flavor with twenty servings.

Huge Nutrition Magnify

Magnify’s advanced nitric oxide formula is one of the best nitric oxide boosters on the market. It promises to offer the highest-dosed pump pills out there with scientifically-backed ingredients.

  • Scientifically-backed ingredients
  • The supplement can be stacked with other products
  • Made in the USA
  • You have to take a whopping five capsules before a workout

This formula includes the following ingredients L-arginine, beetroot extract, L-citrulline, Norvaline (green coffee bean extract, tart cherry, blueberry, broccoli, & kale), Bioperine, and Green Tea Extract. 

In contrast to what some reports claim, L-arginine is an amino acid that plays a big part in nitric oxide production. Consequently, this plays an essential role in regulating the body’s blood pressure and immune system. 

Furthermore, some evidence has shown[6] that L-arginine can help lower blood pressure. Therefore, L-arginine is a fantastic ingredient in this product. 

Additionally, this product has excellent reviews from real customers. Nitric Oxide advanced formula is made in the United States in an FDA-approved facility. 

BlueEarth’s L-Arginine + L-Citrulline

This dietary supplement blend is targeted for cardiovascular health, nitric oxide boosting, and supporting your blood pressure. Boosting nitric oxide levels within the blood vessel wall will help the blood vessels relax and lower blood pressure.

  • Cardio health formula
  • Blood pressure support
  • Affordable
  • Not FDA- approved

The main ingredients within this supplement are L-arginine and L-citrulline. These powerful ingredients are known for producing nitric oxide. It is made in the United States, comes in multiple flavors, and is easy to mix.  

You can also find additional vitamin nutrients within this supplement like vitamin D, vitamin C, and vitamin B12. Furthermore, customers are extremely satisfied with this product giving it a five-star review.

SNAP Nitric Oxide Organic Beets

Coming up next is the organic beets nitric oxide booster made by SNAP supplements. This supplement aims to support heart muscle function, help with cholesterol levels, support cardiovascular health, and increase energy levels.

  • Supports blood vessels
  • Non-GMO, gluten-free, and vegan
  • 90-day money-back guarantee
  • Includes proprietary blend

Organic beetroot can be found in many nitric oxide-boosting supplements. Some of the best nitric oxide supplements on the market contain beetroot. Beetroot helps widen blood vessels, which in turn enhances circulation and blood flow. Therefore, beetroot is a great natural supplement for reducing cardiovascular disease. 

You can find SNAP Nitric Oxide Booster powder supplements in a few different flavors. Just add one scoop to any beverage of choice and stir it up. 

Additionally, some users like to use Organic Beet as a pre-workout, and it does not contain caffeine, so you can avoid unwanted side effects from that.

Huge Pump Serum Pre-Workout

This stimulant-free pre-workout formula contains high-quality ingredients that work together to optimize muscle pumps, help with focus, and increase workout performance. 

  • Stackable with other products
  • Stimulant-free pre-workout
  • Helps with focus & endurance
  • Expensive
  • Only available online

In one scoop, you get a variety of excellent ingredients like beetroot extract, pomegranate extract, Bioperine, and Nitrosigine. As we know, beetroot extract is an ideal supplement for increasing nitric oxide. Additionally, some studies[7]have found that pomegranate extract is beneficial for increasing blood flow and expanding blood vessels.

This nitric oxide boosting supplement is popular with men and made in the United States. The company is proud of its ingredients and promises to only manufacture them in a GMP-certified facility that is FDA-approved. However, this product is expensive and has limited flavor options.

Are Nitric Oxide Supplements Safe?

Is this supplement too good to be true? Is it safe to consume? Nitric oxide supplements are generally safe. However, there is a risk of mild side effects with any supplement. Some individuals have experienced stomach discomfort and headaches. You must take the product as directed by the manufacturer for it to operate optimally.

Additionally, as mentioned above, you can naturally get nitric oxide benefits through your diet. So if you have any unwanted side effects from dietary supplements, then increased dietary intake is the best route to go.

What Is Nitric Oxide?

Nitric Oxide is a molecule produced naturally within the body that can be increased through dietary supplements. These supplements help dilate blood vessels, allowing blood flow and controlling healthy blood pressure levels.

Additionally, it is an essential factor for your immune system. Nitric oxide can be consumed naturally in foods like spinach, carrots, beetroot, and cauliflower. 

Benefits Of Nitric Oxide Supplements

Nitric Oxide supplementation is optimal for those who are working to support muscle growth. Not only is it great for muscle growth, but it is also great for cardiovascular health and controlling blood pressure. 

Believe it or not, nitric oxide supplements can also help with erectile dysfunction. For instance, evidence[8] has found that L-arginine and L-citrulline may help patients with erectile dysfunction.

Potential Side Effects

Although nitric oxide is typically healthy and safe for consumption, too much of anything can cause adverse effects. Some mild side effects may arise, such as diarrhea, stomach discomfort, headaches, and nausea. 

Additionally, it is crucial to check nitric oxide supplements for ingredients that may cause an allergic reaction. We highly recommend reaching out to your professional medical physician before starting any new supplement, especially taking other supplements or medications.  

Furthermore, ensure that you take the recommended dosage listed on the product. Do not exceed the recommended dose to avoid any adverse effects. 

How To Choose The Best Nitric Oxide Booster

It is important to choose a nitric oxide booster that is right for you. The best nitric oxide supplement will have quality ingredients that are scientifically backed by evidence. 

You should ensure that the supplement has enough of the ingredients to see results and be effective enough to increase nitric oxide production. 

Final Thought

Overall, boosting nitric oxide production seems beneficial for building muscle growth, enhancing blood vessel health, and improving muscle pumps in the gym. 

We recommend taking a look at the ingredients in the product to see that you are getting the best bang for your buck. Look at customer reviews for potential problems with the product or company or possible side effects not noted elsewhere.

Frequently Asked Questions

Does nitric oxide have to be taken as a supplement, or can you find it in food?

No! Nitric oxide can be found in many food sources, and these foods will increase nitric oxide levels within your body. Some of the most popular are beets, pomegranates, and dark leafy greens, like spinach.

Can I take nitric oxide supplements to help lower my blood pressure? 

Nitric oxide allows the blood vessels to relax, increase blood flow, and lower blood pressure. Therefore, yes, nitric oxide can help lower your blood pressure.

Do nitric oxide supplements cause you to gain weight?

No, taking nitric oxide supplements does not cause you to gain weight. You need to check the supplement before taking it, though, for added sugars or fillers that may cause weight gain.

Should you take nitric oxide supplements if you have high blood pressure?

When taking supplements with prescription medications, you risk the chance of having interactions. So if you have a medical condition, you must check with a medical professional before starting a nitric oxide supplement.

Do nitric oxide-boosting ingredients contain caffeine or other stimulants?

Yes and no. Not all products made to increase nitric oxide are made with caffeine or other added stimulants. Several supplements on the market are stimulant-free. This is great news for those sensitive to caffeine who want to avoid it altogether. 


+ 8 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Bloomer, R.J., Farney, T.M., Trepanowski, J.F., McCarthy, C.G. and Canale, R.E. (2011). Effect of betaine supplementation on plasma nitrate/nitrite in exercise-trained men. Journal of the International Society of Sports Nutrition, [online] 8(1). Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3066115/#:~:text=With%20regards%20to%20betaine%20and,nitrite%2C%20a%20surrogate%20marker%20of
  2. Rogers, J.M., Gills, J. and Gray, M. (2020). Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults. Journal of the International Society of Sports Nutrition, [online] 17(1). Available at: https://pubmed.ncbi.nlm.nih.gov/32093766/
  3. Gonzales, J.U., Raymond, A., Ashley, J. and Kim, Y. (2017). Doesl-citrulline supplementation improve exercise blood flow in older adults? Experimental Physiology, [online] 102(12), pp.1661–1671. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5999519/
  4. Alvares, T., Conte-Junior, C., Silva, J. and Paschoalin, V.M. (2012). Acute L-Arginine supplementation does not increase nitric oxide production in healthy subjects. Nutrition & Metabolism, [online] 9(1), p.54. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3489573/
  5. Domínguez, R., Cuenca, E., Maté-Muñoz, J., García-Fernández, P., Serra-Paya, N., Estevan, M., Herreros, P. and Garnacho-Castaño, M. (2017). Effects of Beetroot Juice Supplementation on Cardiorespiratory Endurance in Athletes. A Systematic Review. Nutrients, [online] 9(1), p.43. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5295087/
  6. McRae, M.P. (2016). Therapeutic Benefits of l-Arginine: An Umbrella Review of Meta-analyses. Journal of Chiropractic Medicine, [online] 15(3), pp.184–189. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5021928/
  7. Roelofs, E.J., Smith-Ryan, A.E., Trexler, E.T., Hirsch, Katie R. and Mock, M.G. (2016). Effects of pomegranate extract on blood flow and vessel diameter after high-intensity exercise in young, healthy adults. European Journal of Sport Science, [online] 17(3), pp.317–325. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5563971/
  8. Barassi, A., Corsi Romanelli, M.M., Pezzilli, R., Damele, C.A.L., Vaccalluzzo, L., Goi, G., Papini, N., Colpi, G.M., Massaccesi, L. and Melzi d’Eril, G.V. (2017). Levels of l -arginine and l -citrulline in patients with erectile dysfunction of different etiology. Andrology, [online] 5(2), pp.256–261. Available at: https://pubmed.ncbi.nlm.nih.gov/28178400/‌

Medically reviewed by:

Kathy Shattler

Alycia Watts is a freelance writer with a Bachelor’s degree in Business Administration (BBA). She has a passion for all topics involving lifestyle, health, and nutrition. Her goal is to educate others and share her passion. When she is not reading or writing, she enjoys spending time with family and friends.

Medically reviewed by:

Kathy Shattler

Journal of Physical Education and Sport

Trusted Source

Go to source

SciELO - Scientific Electronic Library Online

Trusted Source

Go to source

African Journals Online

Non-profit Platform for African Journals

Trusted Source
Go to source

Journal of The American Board of Family Medicine

American Board of Family Medicine

Trusted Source
Go to source

Informit

RMIT University Library

Trusted Source
Go to source

European Food Safety Authority

Science, Safe food, Sustainability

Trusted Source
Go to source

OrthoInfo

American Academy of Orthopaedic Surgeons

Trusted Source
Go to source

American Academy of Family Physicians

Strengthen family physicians and the communities they care for

Trusted Source
Go to source

Agricultural Research Service

U.S. Department of Agriculture

Trusted Source
Go to source

The American Journal of Medicine

Official Journal of The Alliance for Academic Internal Medicine

Trusted Source
Go to source

National Institute on Alcohol Abuse and Alcoholism

Database From National Institute Of Health

Trusted Source
Go to source

Lippincott Journals

Subsidiaries of Wolters Kluwer Health, Inc.

Trusted Source
Go to source

National Institute on Aging

Database From National Institute Of Health

Trusted Source
Go to source

Translational Research

The Journal of Laboratory and Clinical Medicine

Trusted Source
Go to source

Cell

An All-science Publisher

Trusted Source
Go to source

Journal of Translational Medicine

BioMed Central

Part of Springer Nature
Go to source

Federal Trade Commission

Protecting America's Consumers

Trusted Source
Go to source

National Human Genome Research Institute

Database From National Institute Of Health

Trusted Source
Go to source

Food Production, Processing and Nutrition

BioMed Central

Part of Springer Nature
Go to source

BMC Gastroenterology

BioMed Central

Part of Springer Nature
Go to source

ACS Publications

A Division of The American Chemical Society

Trusted Source
Go to source

Annual Reviews

Independent, Non-profit Academic Publishing Company

Trusted Source
Go to source

PubChem

National Center for Biotechnology Information

National Library of Medicine
Go to source

PLOS Journals

Nonprofit Publisher of Open-access Journals

Trusted Source
Go to source

Thieme E-books & E-Journals

Peer-reviewed & Open Access Journal

Trusted Source
Go to source

European Journal of Agriculture and Food Sciences

Peer-reviewed International Journal Publishes

Trusted Source
Go to source

Royal Society of Chemistry Publishing Home

Chemical Science Journals, Books and Database

Trusted Source
Go to source

Frontiers

Publisher of Peer-reviewed Articles in Open Acess Journals

Trusted Source
Go to source

De Gruyter

German Scholarly Publishing House

Trusted Source
Go to source

Hindawi

Open Access Research Journals & Papers

Trusted Source
Go to source

Oilseeds and Fats, Crops and Lipids

EDP Sciences

Trusted Source
Go to source

Cambridge Core

Cambridge University Press

Trusted Source
Go to source

FoodData Central

U.S. Department Of Agriculture

Trusted Source
Go to source

Journal of the American Heart Association

Peer-reviewed Open Access Scientific Journal

Trusted Source
Go to source

National Center for Complementary and Integrative Health

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

The Americans with Disabilities Act

U.S. Department of Justice Civil Rights Division

Trusted Source
Go to source

Journal of the Academy of Nutrition and Dietetics

Organization of Food and Nutrition Professionals

tr
Go to source

Sage Journals

Database From Sage Publications

Trusted Source
Go to source

National Institute of Drug Abuse

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

The ClinMed International Library

A Repository and an Open Access Publisher for Medical Research

Trusted Source
Go to source

The Royal Society Publishing

United Kingdom's National Academy of Sciences

Trusted Source
Go to source

APA PsycNet

Database From American Psychological Association

Trusted Source
Go to source

The Pharma Innovation Journal

Peer-reviewed And Refereed Journal

Trusted Source
Go to source

Asian Journal of Pharmaceutical Research and Development

Peer-reviewed Bimonthly Journal

Trusted Source
Go to source

British Pharmacological Society

Journals - Wiley Online Library

Trusted Source
Go to source

American Psychological Association

Scientific and Professional Organization of Psychologists

Trusted Source
Go to source

AAP Publications

Database From American Academy of Pediatrics

Trusted Source
Go to source

Karger Publishers

Academic Publisher of Scientific and Medical Journals and Books

Trusted Source
Go to source

Cambridge University Press & Assessment

Database From Cambridge University

Trusted Source
Go to source

National Institute of Mental Health

Database From National Institute Of Health

U.S. Department of Health and Human Services
Go to source

MDPI

Publisher of Open Access Journals

Trusted Source
Go to source

Bulletin of the National Research Centre

Part of Springer Nature

Trusted Source
Go to source

The New England Journal of Medicine

Massachusetts Medical Society

Trusted Source
Go to source

Economic Research Service

U.S. DEPARTMENT OF AGRICULTURE

Trusted Source
Go to source

MedlinePlus

Database From National Library of Medicine

U.S Department of Health and Human Services
Go to source

National Institute of Health

An agency of the U.S. Department of Health and Human Services

Trusted Source
Go to source

Trusted Source

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

The BMJ

Weekly Peer-reviewed Medical Trade Journal

The British Medical Association
Go to source

The British Psychological Society

The British Psychological Society is a charity registered in England

Database From Wiley Online Library
Go to source

National Heart, Lung, and Blood Institute

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

PubMed

Database From National Institute Of Health

U.S National Library of Medicine
Go to source

DailyMed

Database From National Institute Of Health

U.S National Library of Medicine
Go to source

Google Scholar

Go to source

Science.gov: USA.gov for Science

Government Science Portal

Go to source

ResearchGate

Social Network Service For Scientists

Find and share research
Go to source

American Heart Association

To be a rentless force for a world of longer, healthier lives

Go to source

BioMed Central

Research in progress

Go to source

JAMA Network

Home of JAMA and the Specialty Journals of the American Medical Association

Go to source

Springer Link

Database From Springer Nature Switzerland AG

Springer - International Publisher Science, Technology, Medicine
Go to source

ODS

Database from Office of Dietary Supplements

National Institutes of Health
Go to source

Federal Trade Commission

Bureaus of Consumer Protection, Competition and Economics
Go to source

Trusted Source

Database From U.S. Department of Health & Human Services

Governmental Authority
Go to source

Oxford Academic Journals

Oxford University Press

Trusted Source
Go to source

Taylor & Francis Online

Peer-reviewed Journals

Academic Publishing Division of Informa PLC
Go to source

WHO

Database from World Health Organization

Go to source

Journal of Neurology

Peer-reviewed Medical Journal

American Academy of Neurology Journal
Go to source

ScienceDirect

Bibliographic Database of Scientific and Medical Publications

Dutch publisher Elsevier
Go to source

Wiley Online Library

American Multinational Publishing Company

Trusted Source
Go to source

Centers for Disease Control and Prevention

U.S. National Public Health Agency

U.S Department of Health and Human Services
Go to source

Trusted Source

Database from U.S. National Library of Medicine

U.S. Federal Government
Go to source

U.S. Food & Drug Administration

Federal Agency

U.S Department of Health and Human Services
Go to source

PubMed Central

Database From National Institute Of Health

U.S National Library of Medicine
Go to source
Feedback

Help us rate this article

Thank you for your feedback

Keep in touch to see our improvement