Fact checkedFact Checked

This article is reviewed by a team of registered dietitians and medical doctors with extensive, practical clinical and public health experience.

 

Top 7 Best Pre-Workout Supplements To Buy in 2022

mitchelle-Morgan

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

All articles are produced independently. When you click our links for purchasing products, we earn an affiliate commission. Learn more about how we earn revenue by reading our advertise disclaimer.

Transparent Labs BULK Pre-Workout

Transparent Labs BULK

  • Gluten, additives, and synthetics-free.
  • May Improve exercise endurance.
  • Ingredients are science-backed.

Creatine (CrazyBulk)

Crazy Bulk

  • Promotes faster muscle recovery
  • The brand offers free shipping.
  • Contains five types of creatine

optimum nutrition

Optimum Nutrition

  • Contains whey protein isolate
  • Comes in a variety of flavors.
  • The brand has a good reputation

Every workout enthusiast wants an extra rush of energy to get through the challenging workouts, adding muscle mass and improving mental clarity. You boost physical and mental energy through the best pre-workout supplements. Companies offer many supplements that claim to provide some or all of these advantages.

Which one do you choose if you want to increase your muscle endurance, reduce muscle cramps and fatigue, lose weight, or increase your energy level?

The pre-workout nutrition supplements have been designed to be ingested fifteen to forty-five minutes before you start exercising. Studies[1] show that they are the most effective during this period.

In this article, we will discuss the best pre-workout supplement and more and provide seven of the best pre-workout supplements that can assist you in achieving meaningful workout benefits.

Best Best Pre-Workout Supplements on the market in (September. 2022)

What Is Inside Pre Workout Pill?

Stimulant-free pre-workout pills contain numerous ingredients, some of which may be organic and natural, while others are synthetic and inactive, such as flavoring, dyes, and coloring. This combination of active ingredients generally constitutes stimulants, amino acids, and plant extracts.

Here are some of the common ingredients that you will find in most good pre-working-out supplements:

  • Stimulants[2] like natural caffeine. These stimulants help boost energy-giving one the gusto to keep going and hitting the exercise routine one milestone after another.
  • Citrulline malate[3] is a kind of amino acid. It is believed that citrulline boosts nitric oxide production. Nitric oxide is a powerful chemical that stimulates blood flow to the working muscles.
  • Creatine[4] is also another kind of amino acid, also called Creapure. Creatine helps to increase the energy, power, and size of your muscles. In compliance with stringent quality and purity criteria, Creapure is a patented type of creatine manufactured artificially.
  • Amino acids with branched chains (BCAAs). The BCAAs[5] (branched-chain amino acids) – L-valine, L-leucine, and L-isoleucine—are essential for muscle rehabilitation and growth.
  • Rhodiola rosea[6] is a flowering plant. Rhodiola rosea, often referred to as the golden root extract, may help to reduce weariness after physical activity.

We shall look at more pre-workout ingredients as we cover each product below.

The Line Up At A Glance

Transparent Labs BULK Pre-Workout

Editor’s choice

Transparent Labs BULK

  • Gluten, additives, and synthetics-free.
  • May Improve exercise endurance.
  • Ingredients are science-backed.

Creatine (CrazyBulk)

Best Creatine pre-workout supplment

Crazy Bulk

  • Promotes faster muscle recovery
  • The brand offers free shipping.
  • Contains five types of creatine

optimum nutrition

Best whey protein supplement

Optimum Nutrition

  • Contains whey protein isolate
  • Comes in a variety of flavors.
  • The brand has a good reputation.

Jacked Factory NITRO SURGE Shred

Best pre-workout supplement for pumps

Jacked Factory NITRO SURGE Shred

  • Well researched elements.
  • Transparent labeling.
  • Affordable supplement

Best for beginners

Onnit Total Strength and Performance

  • Consists of 3 proprietary blends.
  • Beginner-friendly.
  • May enhance energy and performance.

15% Off Coupon: HEALTHCANAL15

nutrabio

Best pre-workout supplement for muscle gain

NutraBio

  • Contains 22 ingredients
  • Available in different flavors
  • Well-dosed

Huge Supplements Wrecked

Best tasting supplement

Huge Supplements Wrecked

  • Strongest pre-workout supplement.
  • Contains high doses of active ingredients.
  • It has incredible taste.

7 Best Pre-Workout Supplements and Powders 2022

Transparent Labs Bulk

This Transparent Labs BULK pre-workout pill may be the best on the market. It is gluten-free devoid of artificial ingredients, colors, and sugars.

  • It is a third-party lab-tested formula. 
  • It has brain-boosting ingredients.
  • It has muscle and exercise endurance-boosting ingredients.
  • It is free from synthetic additives like colors and dyes.
  • It is gluten-free.
  • It can help increase testosterone levels for men.
  • The price is a bit higher for most users.

Here is the entire ingredient profile that Transparent Labs BULK contains.

  • The amino acid beta-alanine[7] has a close correlation to stamina. This pre-workout BULK provides a massive four-gram dose. Beta-alanine causes a harmless tingling feeling on the skin, and four grams can be too much for those who don’t enjoy it.
  • Betaine[8] has been found to boost energy output in several trials using powerlifting activities such as squatting, bench press, and deadlift. There’s a 2.5-gram dosage in this pre-workout supplement.
  • BCAAs like leucine, isoleucine, and valine can help in muscle preservation, stamina, fat reduction, and concentration. BULK contains four grams, which is a good amount for a pre-workout.
  • There are 180 milligrams of anhydrous caffeine in this, which is around the same amount [9]as two 8 oz. cups of coffee.
  • Citrulline[10] is organically found in organ meats, beans, and watermelon, and it can improve energy output and exercise stamina. BULK includes 6 grams of citrulline malate, a combination of citrulline and malic acid that may aid absorption.
  • Tyrosine, taurine, and theanine can all help you stay focused during your workouts. This supplement contains 1.3 grams, 600 milligrams, and 360 milligrams, respectively.

This pre-workout supplement has 30 mg of 270% of the Daily Value (DV) for zinc[11], 75 mcg of the Vitamin D3[12] 380% of the DV, and three milligrams of boron[13] which has no DV established. Vitamin D and zinc are both connected to a healthy amount of testosterone.

Crazy Bulk

Creatine (CrazyBulk)

CrazyBulk USA is a terrific firm that supplies fitness supplements. They are known for having one of the most comprehensive bodybuilders and shaping supplements available. Creatine is the main ingredient in the product.

  • There are five different forms of creatine in the mix.
  • The brand has a positive image.
  • It improves endurance, strength, and stamina.
  • It helps you regain strength and hydration after an exercise.
  • For some people, it may be a little pricey.

Crazy Bulk is undoubtedly one of the best pre-workout supplements available for buying online. Given CrazyBulk’s fantastic reputation and the fact that it contains five types of creatine in high concentrations, it is the reason many bodybuilders adore this product.

CrazyBulk is different from the other supplements on our list in that it contains several different types of the same ingredient. CRN-5 is made up of five separate muscle-building compounds. Other beneficial constituents in CrazyBulk CRN-5 include potassium, sodium, and magnesium, the three essential components that give the body electrolytes. 

The three ingredients act together to allow the body to hydrate and restore strength after a rigorous workout.

Ingredients in CRN-5 include

  • Creatine citrate pyruvate[14] enhanced performance during intensive exercises in a double-blind, placebo-controlled study.
  • Aquamin Mg and Aquamin AG are two supplements that aid in protein synthesis and muscle building, which are essential after an exercise. As a result, it’s great for assisting you in quickly recovering[15] from strenuous activities.
  • Monohydrate creatine[16] aids in the body’s natural fat-free bulk and strength gains.
  • A study indicated that creatine hydrochloride, HCL, in the pre-workout supplement, greatly enhances[17] weightlifters’ bench press and leg press routines in a month.
  • According to one randomized, double-blind study[18], when creatine ethyl ester is combined with resistance exercise, it improves muscular strength and muscle mass in non-athletic men.
  • Potassium and Tri-Sodium help keep your body hydrated and give you extra energy during your workouts. When these two compounds are released, they naturally produce muscle exhaustion, but adding them to your diet[19] provides the muscle with additional power.
  • Tri-Creatine Malate[20] is essential for professional long-distance runners, as seen in a study. They claim that their running distance significantly increased once they were on it. They also improved their endurance and speed on the racetrack.

Optimum Nutrition

optimum nutrition

Optimum Nutrition is described on the official site as “one of the most trusted brands in the sports nutrition market.” And they have positive client reviews to support that claim.

The supplement comes in various flavors, including Blueberry Lemonade, Green Apple, Watermelon, and Fruit Punch.

  • L-citrulline, creatine, and L-carnitine are included in the composition.
  • Some vital vitamins are included in the formula.
  • The recipe has a pleasant aroma and flavor.
  • It’s from a well-known brand.
  • 175 milligrams per scoop of caffeine could be too much for some people.
  • It is not certain if it’s vegan or vegetarian friendly.

This supplement combines various ingredients, including amino acids, vitamins, and caffeine. Let’s take a look at some of the formula’s primary components.

  • A popular post-workout supplement in this blend is creatine monohydrate.
  • Vitamins B6 and B12[21] both aid in the standard release of energy and the reduction of exhaustion and fatigue.
  • Caffeine included in one scoop contains a total of 175 milligrams of caffeine. To put this in perspective, a standard cup of coffee should contain roughly 100 mg of caffeine.
  • Pantothenic acid, generally known as Vitamin B5, helps to maintain normal energy levels, reduce exhaustion and fatigue, and maintain typical mental performance.
  • Vitamin D is a necessary vitamin that our bodies produce naturally when our skin is exposed to UVB radiation from direct sunshine. Vitamin D is also found in some foods and as a supplement. Vitamin D is present in each pre-workout serving in the amount of 500 IU.
  • Beta-Alanine is a common pre-workout component, with 1.5 g in each serving of this pre-workout supplement.
  • The amino acid L-citrulline is found in watermelons. Gold Standard Pre-Workout includes 750 mg per serving. This is a far lower dosage than some comparable items.

NutraBio

nutrabio

This pre-workout supplement features a completely disclosed recipe, no synthetic chemicals, and a variety of excellent flavors featuring the new Blue Razz.

  • Available in 6 flavor varieties.
  • The product is well-dosed and easy to incorporate into your diet.
  • Effective pre-workout supplement that offers you a plethora of benefits.
  • It might not be beginner-friendly.

The pre-workout supplement contains 22 science-backed ingredients. They are included in the following blends:

Power, Strength, and Endurance Complex

The most well-known and researched of the three BCAAs is leucine[22] dosed at 3.5 mg in this supplement. Leucine can minimize muscle atrophy caused by exercise, speed up the healing process, and increase muscle strength in addition to stimulating protein synthesis.

Beta-alanine, best known for its tingling feelings, is a beneficial endurance-boosting ingredient. Carnosine concentrations[23] in muscle cells are increased by beta-alanine, which strengthens your fibers’’ ability to cushion acidic ions. As a result, you’ll have more stamina and experience less “heat” in your muscles while exercising.

Creatine, 3 grams (g), helps you gain muscle mass, stamina, energy, and endurance. It also has some mental benefits and helps with hydration.

Betaine isn’t simply for strength; it also helps creatine work better. Betaine is a choline metabolite that acts as a methyl donor and osmolyte in the body. As a result, it helps prevent dehydration and converts homocysteine to methionine, a precursor of creatine.

Malic acid[24], 1.7 g, assists in the metabolism of carbohydrates, proteins, and lipids into valuable forms of energy throughout the Krebs cycle. Malic acid deficiency can decrease Krebs’s cycle function, causing you to become fatigued more quickly.

Creatine MagnaPower, 500 g, is a chelated magnesium-bound version of creatine that boasts better bioavailability and supposedly has superior mixability. 

Nitrix Matrix Pump:

  • 6 grams of L-citrulline
  • 1 gram of Agmatine[25]

Focus and Stim Matrix:

  • 1.5 grams of L-tyrosine
  • 500 milligrams of Choline Bitartrate
  • 350 milligrams of caffeine
  • 100 mcg of Huperzine A

Electrolyte and hydration optimizer:

  • 2 grams of Taurine[26]
  • 525 milligrams of Calci-K
  • 189 milligrams of Sodium Phosphate

Jacked Factory NITRO SURGE Shred

Jacked Factory NITRO SURGE Shred

Each serving of this supplement contains a fully transparent dose of seven scientifically proven ingredients, the majority of which aid in muscle growth. This is in addition to the fundamental pre-workout effects of better concentration, higher energy levels, and more blood flow to the muscle cells.

  • There are a lot of science-backed components.
  • The dosages of the ingredients are also science-backed.
  • The product has clear labeling.
  • It is competitively priced.
  • The citrulline levels are low.
  • The formula contains artificial tastes and sweeteners.

The pre-workout from Jacked Factory is inexpensive, comes in 13 flavors, and has fully-dosed substances that may aid muscular building. 

It has the following list of ingredients:

  • Citrulline[27]
  • 1.6 grams beta-alanine
  • 1.25 g anhydrous betaine[28]
  • 90 mg of theanine
  • 50 mg theobromine[29]
  • 180 mg Caffeine
  • 25 mg AstraGin®: a proprietary, 100% natural compound containing Astragalus Root Extract and San-qi Ginseng Root Extract. It promotes a healthy gut environment by promoting a healthy gut environment increasing nutrient uptake.
  • Sucralose and acesulfame potassium are the sweeteners included.

Sucralose is a controversial supplement with documented adverse effects[30] on the gut microbiome. It also adversely affects blood sugar when combined with carbohydrate-containing foods.

Huge Supplements Wrecked

Huge Supplements Wrecked

As the best tasting pre-workout supplements, everybody will enjoy having it in their daily protein shake. Favorite for beginners. Pre-workout servings should be used conservatively.

  • It is a very potent pre-workout supplement.
  • It contains high doses of pre-workout ingredients, making it a potent muscle gainer.
  • It tastes amazing.
  • Have high dosage, so its use should be sparingly. Excess dosage may be harmful.

This supplement contains the following list of pre-workout ingredients:

100 mg Di-Caffeine Malate

Caffeine[31] (75%) and Malic acid (25%) make up this supplement. As a result, digestion is improved, leading to a more consistent release of energy. Di-Caffeine Malate provides longer-lasting energy.

100mg Himalayan Pink Salt

Minerals including potassium, calcium, and magnesium abound in this sort of salt. It aids muscle contraction, performance, and cramp prevention.

S7 (100 mg)

S7 is a patented blend of seven natural plant extracts, including Green Tea, Tart cherry, Broccoli, Kale, Blueberry, Turmeric, and Green Coffee Bean extract.

100 mg hordenine HCl

A powerful stimulant that aids in enhancing energy, attention, and concentration.

75 mg N-Methyltyramine

This substance works as a stimulant and a focus enhancer. It will provide you with assistance during a strenuous and intensive workout.

50 mg theobromine

This is a naturally occurring substance with stimulant effects. It can aid in the development of energy, attention, and motivation.

50 mg Higenamine HCl[32]

Higenamine is a natural chemical that can be found in various Asian plants. It’s a stimulant that can help widen the blood vessels and expand the airways.

20 mg isopropylnorsynephrine[33]

Synephrine is a well-known stimulant that has been tweaked. Synephrine has been shown to improve muscle endurance during resistance training.

1mg Rauwolscine[34]

Rauwolscine is a stimulant comparable to Yohimbine; however, it is considered to be even more potent.

9000 mg L-citrulline malate

The ingredient may aid in the enhancement of athletic performance and as an aide to strength training. It also raises nitric oxide levels, allowing more blood to pass into the muscles for a greater muscle pump. Thus, it may boost performance.

3200 mg Beta-Alanine

Muscle endurance, strength, and tiredness are all improved with this supplement. In clinical investigations, it has also been demonstrated to potentially improve lean muscle mass.

2000 mg Agmatine Sulfate

The key benefit of this substance is that it improves the transport of blood to tissues needing oxygen and nutrient supplies.1250 mg L-tyrosine

This is an amino acid that can aid in enhancing cognitive abilities.

600 mg Lion’s Mane Mushroom[35]

It’s thought to be a good nootropic (brain-boosting) substance. It may have certain advantages, such as lowering stress and cholesterol levels. Antioxidants are abundant as well.

255 mg VasoDrive-AP

A proprietary casein hydrolysate-derived substance that can enhance blood circulation and transport of nutrients.

250 mg Caffeine Anhydrous

Caffeine is a stimulant that helps you perform better in the gym. It will help you improve your workout performance by boosting the number of repetitions you do thus enhancing your strength training.

250 mg Inositol Hexanicotinate[36]

This is a form of niacin that is also referred to as the no-flush niacin. It aids in the dilation of arteries and arterioles so that more blood can flow through.

Onnit Total Strength + Performance

Onnit Total Strength + Performance

15% Off Coupon: HEALTHCANAL15

As a beginner, you always look for a pre-workout that is well-rounded. And Onnit is just that supplement. The ingredients in Onnit Total Strength Performance have been dosed at just the right researched amount, so much of it is effective.

  • It helps with power-boosting during workouts.
  • It improves strength.
  •  It optimizes your performance naturally.
  • There might be some tingly feeling.

The natural ingredients are divided into three primary proprietary blends. They are:

  • The Onnit Perform Blend contains branched-chain amino acids, glutamine[37], and beta-alanine.
  • The Onnit Support Blend contains red clover extract, luteolin, and resveratrol[38].
  • The Onnit Power Blend contains stinging nettle extract[39], D-aspartic acid[40], Eurycoma longifolia root extract[41], and Mucuna pruriens extract[42].
  • Organic Arabic gum, organic rice hull extract, sodium citrate, and Stevia[43] are among the other ingredients, along with 5 mg of black pepper extractions and various other natural flavors.
  • Vitamins B6 and B5, 10% of your daily magnesium intake, plus a small amount of sodium and calcium, round out the list of essential minerals.

How Do We Choose Best Pre-Workout?

Selecting the best pre-workout formula might be a bit daunting since there are so many pre-workout powders and capsules in the market.

Here is a list of things you may be on the lookout for the next time you buy the best pre-workout supplements for improved exercise performance.

Ingredients

There are numerous pre-workout ingredients, and each has its health benefits for gym-goers. When you are looking at the ingredient profile of a pre-workout supplement, ensure to align it with what you need and look for those with natural ingredients.

Are you in need of an energy boost? Or are you looking for a pre-workout to build muscle fast or fight muscle fatigue? Or perhaps you are looking for one that clears your mind and motivates you to work out more. Alternatively, one that helps with fat burning?

Find a pre-workout supplement that offers you what you need regardless of your need.

When it comes to getting the best pre-workout formula, a pro tip is to go with natural pre-workout supplements with no artificial additives.

Price

When it comes to the price tag, you need to ask yourself one question:

Can I afford these pre-workout products long-term?

If the answer to that question is yes, go ahead and purchase and use it to your pleasure. Suppose you cannot foot that bill, get any of the many preferred pre-workout supplements within your budget.

The best person to advise you on the best products should be your physician and trainer. They will suggest affordable pre-workout options that are still effective and good for your health.

Dosage

Many pre-workout supplements contain quantities that have been studied, but some brands do not use doses that have been studied. Others do not even disclose what ingredients they have included.

Citrulline, for instance, must be at least 5 grams. So, if you notice a pre-workout with the values surpassing 5 grams, you might be better off looking for another one.

It’s also worth noting that scientists have not yet researched exact minimal dosage in some cases, such as with tyrosine, so brands end up simply making an approximation.

Whatever the case, ensure that you look at the ingredient profile, check the individual dosing per element, and cross-check with proven studies of what you should take daily.

Customer Reviews

The best way to know the brand reputation is to search what people say about the company and product online. By checking past client reviews through various research and editorial teams’ articles online, you get a first-hand understanding of the experience of using these products.

You need to do an exhaustive search across any platform possible, including e-commerce platforms that sell these supplements. Search for the exact pre-workout product and scroll down to customer reviews. Then read both the good and the bad. If you find that the good remarks surpass the bad, then the product might be worth the money. But if it is the opposite, you may reconsider that product.

Despite the consumer comments, you still have to note that pre-workout supplements do not work for everyone. Everyone has different bodies with different needs. 

Benefits of Pre-Workouts

Significant workout benefits that you get from pre-workout supplements are

  • A boost in mental and physical energy.
  • Better athletic performance
  • Better muscle endurance.
  • Faster muscle recovery.
  • Less muscle fatigue.
  • Faster weight loss.
  • Boost in metabolic rate and protein synthesis.

What To Consider Before Buying?

Before keying in your card details at the checkout point after selecting your preferred bodybuilding supplement to use before working out, please consider the following factors:

Third-Party Testing

Third-party testing of a dietary supplement is fundamental. These labs are independent labs that are not associated with the company making the brand, so the results are usually unbiased and unfiltered. If a brand is openly offering the result of these tests, then you can trust the workout supplement brand.

Ensure that the facilities are FDA-approved and GMP-compliant. GMP stands for good manufacturing practices and assures that the facilities comply with FDA regulations.

The Authenticity of the Seller

Sports nutrition is a multi-million industry, and thousands of dietary supplement vendors understand this. Unfortunately, some sellers are just in business to make an extra buck, even if it means duping the unsuspecting seller.

So they end up sourcing substandard pre-workout supplements and supplying them. The results are not always pleasant as the possibility of adverse reactions is higher since their constituents are not as the supplier intended.

To mitigate this, you have to buy your workout supplements from a trusted and verified seller. On that note, the best place to get authentic workout products is the manufacturer’s official website. And if you must use third-party e-commerce sites, ensure that they are verified and trusted. Most of these sites will have ratings on the vendor, so be keen to check this out.

The Type of Pre-Workout Supplement

There are many products in the pre-workout supplement space based on their ingredients. They are also categorized according to the need the consumer has.

Here are some of the kinds that you need to look at before going ahead and just buying the first that pops on an ad:

  • Pre-workout for women.
  • Pre-workout for men.
  • Pre-workout for weight loss.
  • Pre-workout for muscle gain.
  • Pre-workout for running.
  • Thermogenic pre-workout for fat burning.
  • Pre-workout for pumps.
  • Stim-free pre-workout supplements.
  • Vegan pre-workout supplements.
  • Natural pre-workout products.
  • Caffeine-free pre-workout supplements.
  • Creatine-free pre-workout supplements.

You will find many more in the market when looking for the best pre-workout bodybuilding. Other brands that we did not dive into, like Cellucor Pre-Workout Powder, Ladder Pre-workout, Pre-workout NSP Nutrition, and Steria Performance Blend, also have commendable features that you may need.

All in all, the catch is that you get an excellent pre-workout supplement aligned with what you require. You do not have to go for the most popular pre-workout supplements; go for what you need.

Your Health Status

Your overall health status is essential before buying a pre-workout supplement. For this part, you need a medical evaluation from a trained medical specialist on dietary supplements. This may be a licensed dietitian or your physician.

They shall carry out a few tests to see if you are fit to use any of the popular supplements advertised. After a comprehensive assessment, the health professional will suggest a few pre-workout supplements that may fit your body.

If they find that perhaps you have issues like high blood pressure that some ingredients may trigger and make worse, they will suggest an ingredient profile that is safe for you. Your health professional should also address any potential drug-nutrient interactions.

Final Thought

With the best pre-workout powders and pills, you are bound to gain more from intense workouts. Almost every company making a pre-workout supplement claims their product is the best. They might indeed be the best for another person, while for you, it is not. And this is why you need medical evaluations before proceeding to buy any.

The bodybuilding supplements and other pre-workout supplements work, but they do not work alone. You still need to change your eating habits and adapt to healthy habits such as exercising to see the results. That is the only way they work: diet and exercise!

Frequently Asked Questions

1. What does a pre-workout do?

A good pre-workout supplement contains ingredients that improve blood flow and supply oxygen and nutrients to muscle cells. This allows you to push through complex exercise sets, lift larger weights, and maintain good form. They improve stamina, cognitive health, and overall wellness.

2. Is pre-workout bad for you?

No, they are not. It can only be harmful if you use it for an unintended purpose or overdose to hasten the results.

3. How much caffeine is in a pre-workout?

Caffeine content in pre-workout supplements ranges from 150 milligrams to 300 milligrams per serving. There is about 96.5 mg of caffeine in one 8 oz. cup of coffee. If you’re caffeine sensitive, try taking a lower dose or looking for natural alternatives to enhance your vitality before a session.

4. Should I drink pre-workout before or during a workout?

Pre-workout supplements have been designed to be taken before you start exercising. They can boost your energy and stamina, allowing you to perform better during your exercise and maximize your endurance. That’s why pre-workout vitamins should be taken before, not during, activity.


+ 43 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Harty, P.S., Zabriskie, H.A., Erickson, J.L., Molling, P.E., Kerksick, C.M. and Jagim, A.R. (2018). Multi-ingredient pre-workout supplements, safety implications, and performance outcomes: a brief review. Journal of the International Society of Sports Nutrition, [online] 15(1). Available at: https://pubmed.ncbi.nlm.nih.gov/30089501/ [Accessed 19 Feb. 2022].
  2. Grgic, J., Trexler, E.T., Lazinica, B. and Pedisic, Z. (2018). Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. Journal of the International Society of Sports Nutrition, [online] 15(1). Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5839013/ [Accessed 19 Feb. 2022].
  3. Gonzalez, A.M. and Trexler, E.T. (2020). Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Journal of Strength and Conditioning Research, [online] 34(5), pp.1480–1495. Available at: https://pubmed.ncbi.nlm.nih.gov/31977835/ [Accessed 19 Feb. 2022].
  4. Kreider, R.B., Kalman, D.S., Antonio, J., Ziegenfuss, T.N., Wildman, R., Collins, R., Candow, D.G., Kleiner, S.M., Almada, A.L. and Lopez, H.L. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, [online] 14(1). Available at: https://pubmed.ncbi.nlm.nih.gov/28615996/ [Accessed 19 Feb. 2022].
  5. Fouré, A. and Bendahan, D. (2017). Is Branched-Chain Amino Acids Supplementation an Efficient Nutritional Strategy to Alleviate Skeletal Muscle Damage? A Systematic Review. Nutrients, [online] 9(10), p.1047. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5691664/ [Accessed 19 Feb. 2022].
  6. Ballmann, C.G., Maze, S.B., Wells, A.C., Marshall, M.R. and Rogers, R.R. (2018). Effects of short-term Rhodiola Rosea (Golden Root Extract) supplementation on anaerobic exercise performance. Journal of Sports Sciences, [online] 37(9), pp.998–1003. Available at: https://pubmed.ncbi.nlm.nih.gov/30371146/ [Accessed 19 Feb. 2022].
  7. Trexler, E.T., Smith-Ryan, A.E., Stout, J.R., Hoffman, J.R., Wilborn, C.D., Sale, C., Kreider, R.B., Jäger, R., Earnest, C.P., Bannock, L., Campbell, B., Kalman, D., Ziegenfuss, T.N. and Antonio, J. (2015). International society of sports nutrition position stand: Beta-Alanine. Journal of the International Society of Sports Nutrition, [online] 12(1). Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4501114/ [Accessed 19 Feb. 2022].
  8. Hoffman, J.R., Ratamess, N., Kang, J. and Faigenbaum, A. (2009). Effect of Betaine Supplementation on Power Performance and Fatigue. [online] ResearchGate. Available at: https://www.researchgate.net/publication/24145126_Effect_of_Betaine_Supplementation_on_Power_Performance_and_Fatigue [Accessed 19 Feb. 2022].
  9. Lab, P. (2021). Caffeine Anhydrous: Benefits, Weight Loss and Side Effects. [online] Performance Lab®. Available at: https://www.performancelab.com/blogs/stim/caffeine-anhydrous#:~:text=Q%3A%20How%20many%20cups%20of,short%20of%20300mg%20of%20caffeine. [Accessed 19 Feb. 2022].
  10. Gonzalez, A.M. and Trexler, E.T. (2020). Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Journal of Strength and Conditioning Research, [online] 34(5), pp.1480–1495. Available at: https://pubmed.ncbi.nlm.nih.gov/31977835/ [Accessed 19 Feb. 2022].
  11. PeaceHealth. (2015). Health Topics A-Z. [online] Available at: https://www.peacehealth.org/medical-topics/id/hn-3902000#:~:text=A%20double%2Dblind%20study%20of,blood%20flow%20to%20the%20muscles.&text=No%20other%20studies%20of%20the,exercising%20people%20have%20been%20done. [Accessed 19 Feb. 2022].
  12. Wiciński, M., Adamkiewicz, D., Adamkiewicz, M., Śniegocki, M., Podhorecka, M., Szychta, P. and Malinowski, B. (2019). Impact of Vitamin D on Physical Efficiency and Exercise Performance—A Review. Nutrients, [online] 11(11), p.2826. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6893541/ [Accessed 19 Feb. 2022].
  13. Aly, B., Majid Al Busafi and Mahfoodha Alkitani (2020). THE EFFECT OF BORON SUPPLEMENTATION ON FREE TESTOSTERONE ACTIVITY IN THE BLOOD DURING MUSCLE STRENGTH… [online] ResearchGate. Available at: https://www.researchgate.net/publication/342589565_THE_EFFECT_OF_BORON_SUPPLEMENTATION_ON_FREE_TESTOSTERONE_ACTIVITY_IN_THE_BLOOD_DURING_MUSCLE_STRENGTH_TRAINING_OF_VOLLEYBALL_PLAYERS [Accessed 19 Feb. 2022].
  14. Jäger, R., Metzger, J., Lautmann, K., Shushakov, V., Purpura, M., Geiss, K.-R. and Maassen, N. (2008). The effects of creatine pyruvate and creatine citrate on performance during high intensity exercise. Journal of the International Society of Sports Nutrition, [online] 5(1). Available at: https://pubmed.ncbi.nlm.nih.gov/18269769/ [Accessed 19 Feb. 2022].
  15. Singh, N., Aslam, M.N., Varani, J. and Chakrabarty, S. (2013). Induction of calcium sensing receptor in human colon cancer cells by calcium, vitamin D and aquamin: Promotion of a more differentiated, less malignant and indolent phenotype. Molecular Carcinogenesis, [online] 54(7), pp.543–553. Available at: https://pubmed.ncbi.nlm.nih.gov/26076051/ [Accessed 19 Feb. 2022].
  16. Antonio, J. and Ciccone, V. (2013). The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength. Journal of the International Society of Sports Nutrition, [online] 10(1). Available at: https://pubmed.ncbi.nlm.nih.gov/23919405/ [Accessed 19 Feb. 2022].
  17. França, E. de, Avelar, B., Yoshioka, C., Santana, J.O., Madureira, D., Rocha, L.Y., Zocoler, C.A., Rossi, F.E., Lira, F.S., Rodrigues, B. and Caperuto, É.C. (2015). Creatine HCl and Creatine Monohydrate Improve Strength but Only Creatine HCl Induced Changes on Body Composition in Recreational Weightlifters. Food and Nutrition Sciences, [online] 06(17), pp.1624–1630. Available at: https://www.scirp.org/journal/PaperInformation.aspx?PaperID=62283 [Accessed 19 Feb. 2022].
  18. Arazi, H., Eghbali, E. and Mahmood Karimifard (2019). Effect of creatine ethyl ester supplementation and resistance training on hormonal changes, body… [online] ResearchGate. Available at: https://www.researchgate.net/publication/337453524_Effect_of_creatine_ethyl_ester_supplementation_and_resistance_training_on_hormonal_changes_body_composition_and_muscle_strength_in_underweight_non-athlete_men [Accessed 19 Feb. 2022].
  19. MCKENNA, M. (1995). Effects of training on potassium homeostasis during exercise. Journal of Molecular and Cellular Cardiology, [online] 27(4), pp.941–949. Available at: https://pubmed.ncbi.nlm.nih.gov/7563106/ [Accessed 19 Feb. 2022].
  20. Tyka, A.K., Chwastowski, M., Cison, T., Palka, T., Tyka, A., Szygula, Z., Pilch, W., Strzala, M. and Cepero, M. (2015). Effect of creatine malate supplementation on physical performance, body composition and selected hormone levels in spinters and long-distance runners. Acta Physiologica Hungarica, [online] 102(1), pp.114–122. Available at: https://pubmed.ncbi.nlm.nih.gov/25804393/ [Accessed 19 Feb. 2022].
  21. Tardy, A.-L., Pouteau, E., Marquez, D., Yilmaz, C. and Scholey, A. (2020). Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients, [online] 12(1), p.228. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7019700/ [Accessed 19 Feb. 2022].
  22. Raveena Saharan, Pathak, R., Awasthi, M. and Awasthi (2019). Effect of leucine supplementation in muscle growth in gym goers. [online] ResearchGate. Available at: https://www.researchgate.net/publication/333651781_Effect_of_leucine_supplementation_in_muscle_growth_in_gym_goers [Accessed 19 Feb. 2022].
  23. Culbertson, J.Y., Kreider, R.B., Greenwood, M. and Cooke, M. (2010). Effects of Beta-Alanine on Muscle Carnosine and Exercise Performance: A Review of the Current Literature. Nutrients, [online] 2(1), pp.75–98. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3257613/ [Accessed 19 Feb. 2022].
  24. Trichez, D., Clément Auriol, Baylac, A. and Walther, T. (2018). Engineering of Escherichia coli for Krebs cycle-dependent production of malic acid. [online] ResearchGate. Available at: https://www.researchgate.net/publication/326429669_Engineering_of_Escherichia_coli_for_Krebs_cycle-dependent_production_of_malic_acid [Accessed 19 Feb. 2022].
  25. Canakis, J. (2017). The Efficacy and Safety of Six-Weeks of Pre-Workout The Efficacy and Safety of Six-Weeks of Pre-Workout Supplementation in Resistance Trained Rats Supplementation in Resistance Trained Rats. [online] Available at: https://scholarworks.wm.edu/cgi/viewcontent.cgi?referer=&httpsredir=1&article=2011&context=honorstheses [Accessed 19 Feb. 2022].
  26. Kurtz, J.A., VanDusseldorp, T.A., J. Andrew Doyle and Otis, J.S. (2021). Taurine in sports and exercise. [online] ResearchGate. Available at: https://www.researchgate.net/publication/351883483_Taurine_in_sports_and_exercise [Accessed 19 Feb. 2022].
  27. Gonzalez, A.M. and Trexler, E.T. (2020). Effects of Citrulline Supplementation on Exercise Performance in Humans: A Review of the Current Literature. Journal of Strength and Conditioning Research, [online] 34(5), pp.1480–1495. Available at: https://pubmed.ncbi.nlm.nih.gov/31977835/ [Accessed 19 Feb. 2022].
  28. Arumugam, M.K., Paal, M.C., Donohue, T.M., Ganesan, M., Osna, N.A. and Kharbanda, K.K. (2021). Beneficial Effects of Betaine: A Comprehensive Review. Biology, [online] 10(6), p.456. Available at: https://pubmed.ncbi.nlm.nih.gov/34067313/ [Accessed 19 Feb. 2022].
  29. Martínez-Pinilla, E., Oñatibia-Astibia, A. and Franco, R. (2015). The relevance of theobromine for the beneficial effects of cocoa consumption. Frontiers in Pharmacology, [online] 6. Available at: https://pubmed.ncbi.nlm.nih.gov/25750625/ [Accessed 19 Feb. 2022].
  30. gilmerm (2021). Is Sucralose (Splenda) Bad for You? [online] Cleveland Clinic. Available at: https://health.clevelandclinic.org/is-sucralose-splenda-bad-for-you/ [Accessed 19 Feb. 2022].
  31. Canakis, J. (2017). The Efficacy and Safety of Six-Weeks of Pre-Workout The Efficacy and Safety of Six-Weeks of Pre-Workout Supplementation in Resistance Trained Rats Supplementation in Resistance Trained Rats. [online] Available at: https://scholarworks.wm.edu/cgi/viewcontent.cgi?article=2011&context=honorstheses [Accessed 19 Feb. 2022].
  32. Perishable (2019). Higenamine: What Athletes Need to Know to Compete Clean | USADA. [online] U.S. Anti-Doping Agency (USADA). Available at: https://www.usada.org/spirit-of-sport/education/higenamine-what-athletes-need-to-know-to-compete-clean/ [Accessed 19 Feb. 2022].
  33. Mercader, J., Wanecq, E., Chen, J. and Carpéné, C. (2011). Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. Journal of Physiology and Biochemistry, [online] 67(3), pp.443–452. Available at: https://pubmed.ncbi.nlm.nih.gov/21336650/ [Accessed 19 Feb. 2022].
  34. opss. (2020). Rauwolscine and Rauwolfia: Read your label carefully. [online] Available at: https://www.opss.org/article/rauwolscine-and-rauwolfia-read-your-label-carefully [Accessed 19 Feb. 2022].
  35. Syed, Ali, S., Ye, L. and Safdar Ali Wahocho (2018). Lion’s mane mushroom; new addition to food and natural bounty for human wellness: A review. [online] ResearchGate. Available at: https://www.researchgate.net/publication/329781583_Lion’s_mane_mushroom_new_addition_to_food_and_natural_bounty_for_human_wellness_A_review [Accessed 19 Feb. 2022].
  36. Dr Vasudeva Murthy (2011). Efficacy and safety of IHN ( Inositol hexanicotinate) in healthy volunteers with isolated low HDL: A pilot… [online] ResearchGate. Available at: https://www.researchgate.net/publication/261795127_Efficacy_and_safety_of_IHN_Inositol_hexanicotinate_in_healthy_volunteers_with_isolated_low_HDL_A_pilot_study [Accessed 19 Feb. 2022].
  37. Coqueiro, A.Y., Rogero, M.M. and Tirapegui, J. (2019). Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition. Nutrients, [online] 11(4), p.863. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6520936/ [Accessed 19 Feb. 2022].
  38. Baltaci, S.B., Mogulkoc, R. and Baltaci, A.K. (2016). Resveratrol and exercise. Biomedical Reports, [online] 5(5), pp.525–530. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5103661/ [Accessed 19 Feb. 2022].
  39. Toldy, A., Stadler, K., Mária Sasvári and Radak, Z. (2005). The effect of exercise and nettle supplementation on oxidative stress markers in the rat brain. [online] ResearchGate. Available at: https://www.researchgate.net/publication/7875112_The_effect_of_exercise_and_nettle_supplementation_on_oxidative_stress_markers_in_the_rat_brain [Accessed 19 Feb. 2022].
  40. Melville, G.W., Siegler, J.C. and Marshall, P.W.M. (2017). The effects of d-aspartic acid supplementation in resistance-trained men over a three month training period: A randomised controlled trial. PLOS ONE, [online] 12(8), p.e0182630. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5571970/ [Accessed 19 Feb. 2022].
  41. Chen, C., Ooi, F., Abu Kasim, N. and Asari, M. (2019). Effects of Eurycoma Longifolia Jack supplementation combined with resistance training on isokinetic muscular strength and power, anaerobic power, and urinary testosterone: Epitestosterone ratio in young males. International Journal of Preventive Medicine, [online] 10(1), p.118. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6639844/ [Accessed 19 Feb. 2022].
  42. Lampariello, L.R., Cortelazzo, A., Guerranti, R., Sticozzi, C. and Valacchi, G. (2012). The Magic Velvet Bean of Mucuna pruriens. Journal of Traditional and Complementary Medicine, [online] 2(4), pp.331–339. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3942911/ [Accessed 19 Feb. 2022].
  43. Ashwell, M. (2015). Stevia, Nature’s Zero-Calorie Sustainable Sweetener. Nutrition Today, [online] 50(3), pp.129–134. Available at: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4890837/ [Accessed 19 Feb. 2022].
mitchelle-Morgan

Medically reviewed by:

Mitchelle Morgan is a health and wellness writer with over 10 years of experience. She holds a Master's in Communication. Her mission is to provide readers with information that helps them live a better lifestyle. All her work is backed by scientific evidence to ensure readers get valuable and actionable content.

Medically reviewed by:

Harvard Health Publishing

Database from Health Information and Medical Information

Harvard Medical School
Go to source

Trusted Source

Database From Cleveland Clinic Foundation

Go to source

Trusted Source

Database From U.S. Department of Health & Human Services

Governmental Authority
Go to source

WHO

Database from World Health Organization

Go to source

Neurology Journals

American Academy of Neurology Journals

American Academy of Neurology
Go to source

MDPI

United Nations Global Compact
Go to source

Trusted Source

Database From National Institute for Occupational Safety & Health

U.S. Department of Health & Human Services
Go to source

Trusted Source

Database from U.S. National Library of Medicine

U.S. Federal Government
Go to source

Trusted Source

Database From Department of Health and Human Services

Governmental Authority
Go to source

PubMed Central

Database From National Institute Of Health

U.S National Library of Medicine
Go to source