Best Thermogenic Fat Burner 2022: Top 7 Fat Burning Supplements

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Medically reviewed by Kathy Shattler, MS, RDN

PhenQ Supplement

PhenQ

  • Boosts energy and improves mood
  • Five powerful weight loss pills in one
  • 60-day money-back guarantee
  • Backed by science

Up To 50% Off When Buying In Bulk

Leanbean

Leanbean

  • No harmful ingredients
  • Clinically proven glucomannan
  • Boosts energy and focus

instant knockout

Instant Knockout

  • Scientifically formulated 
  • High-quality, natural ingredients
  • Vegan-friendly

Losing weight and burning excess fat are important concerns both women and men have throughout their lives, and they typically are frustrated by a myriad of unsuccessful fad diets and failed weight-loss strategies. Naturally, as their frustration increases with each failure, they tend to reach for something stronger and much more promising: thermogenic fat burners. 

These supplements are popular due to their ease of use, convenience, as well as an abundant number of positive–if not spectacular–reviews posted on the internet. Still, for any particular person, some may be better than others, and it may be challenging to select one as the best personal choice.

Best Thermogenic Fat Burner in (May. 2022)

  • PhenQ – Editor’s choice
  • Leanbean – Most Protency
  • Instant Knockout – Best for Athletes
  • PhenGold – Best All-Natural
  • Trimtone – Most Convenient and User Friendly
  • PrimeShred – Best For Keeping Lean Muscle
  • Okinawa Flat Belly Tonic – Best For Changing Lifestyle Practices

What Is Thermogenic Fat Burner?

A thermogenic fat burner[1] is a weight loss supplement that both increases fat metabolism (disposing of fat) while burning it (energy expenditure), promoting fat loss and weight loss. They typically target stubborn fat areas– which can’t seem to trim up, even with consistent exercise and diet. 

Thermogenic fat burners help increase heat production in the body and suppress appetite, making weight loss and fat loss easier to achieve and maintain. Many increase your energy levels and improve your mood, too, helping you go through the weight loss journey much more easily and smoothly. 

Some brands have other unique ingredients such as specific superfoods that can favorably impact your blood pressure and blood sugar levels, promote liver and gut health, as well as fine-tune your body with antioxidants that fight off disease and neutralize cell-damaging free radicals. 

Without further ado, here are some of the best fat-burning supplements you can find on the market.

The Line Up At A Glance

PhenQ Supplement

Editor’s Choice

PhenQ

  • Boosts energy and improves mood
  • Five powerful weight loss pills in one
  • 60-day money-back guarantee
  • Backed by science

Up To 50% Off When Buying In Bulk

Leanbeanx

Most Potency

Leanbean

  • No harmful ingredients
  • Clinically proven glucomannan
  • Boosts energy and focus

instant knockout

Best For Athletes

Instant Knockout

  • Scientifically formulated 
  • High-quality, natural ingredients
  • Vegan-friendly

PhenGold

Best All-Natural

PhenGold

  • Clinically proven ingredients
  • Reduces cravings
  • Natural ingredients

Up to 55% Off When Buying in Bulk

Trimtone Glucomannan Supplement

Most Convenient and User Friendly

Trimtone

  • Natural ingredients
  • Boosts energy and focus
  • Convenient and easy to use (only one pill)

PrimeShred

Best For Keeping Lean Muscle

PrimeShred

  • Vegetarian & vegan friendly
  • Helps maintain muscle mass while burning fat
  • High potency formula with a 3-step approach

Okinawa Flat Belly Tonic

Best For Changing Lifestyle Practices

Okinawa Flat Belly Tonic

  • Made in an FDA approved and GMPfacility
  • Ease of use (one cup per day)
  • All-natural Japanese formula

How To Choose a Thermogenic Fat Burner?

In order to choose the best out of all fat burner supplements on the market and those explored here, one needs to consider the following:

Sourcing of the ingredients

Are the ingredients all-natural, mostly natural, or a combination of both? Are they natural and synthetically made? Clinically proven ingredients: fat burner supplements aren’t cheap, so always look for those with ingredients such as green tea extract and green coffee bean extract, which have been clinically proven to have thermogenic effects[6] on the human body. 

Manufacturing process

You want a thermogenic fat-burner that is made in an FDA-approved and GMP facility to ensure the high quality, potency, transparency, and safety of all ingredients in the formula. 

Suitability for your diet

If you’re following a vegan or vegetarian diet, it’s important to choose between those thermogenic fat-burner supplements which are suitable for you, e.g., not containing any animal products or by-products.

Price

Even though most thermogenic fat-burning supplements are expensive, there are plenty that offers huge savings when you buy them in bundles of two or three. Also, you may find that focusing on only your primary goals may make less expensive choices as good as the more expensive ones.

Top 7 Best Thermogenic Fat Burner Brands 2022

PhenQ

PhenQ Supplement

Up To 50% Off When Buying In Bulk

PhenQ has been one of the best thermogenic fat burners on the market for years. It is made with 100% natural ingredients and targets fat burning and weight loss from many different angles. It’s the equivalent of five powerful weight loss pills but rolled into one.

  • Boosts energy and improves mood
  • Combines five powerful weight loss pills into one
  • 60-day money-back guarantee
  • Backed by science
  • More expensive when compared with other brands
  • Some ingredients may interact with medications you may already be taking

PhenQ is a well-known brand in the weight loss industry and definitely one that’s the most highly praised. Thousands of satisfied clients use it regularly and swear by its efficacy. 

Its formula is 100% natural and contains capsimax powder (a blend of capsicum, piperine, caffeine, and niacin), caffeine, chromium picolinate, nopal, and L-carnitine fumarate. These ingredients help stimulate heat production in the body and with it, promote fat burning while decreasing the production of new fat, helping maintain a target weight. 

The trademarked α-Lacys Reset® formula also boosts your energy and helps improve your mood, both effects amplifying the other. Phenq has been proven superior to placebo in clinical studies that prove its efficacy. 

Even though it’s a bit on the expensive side, Phenq does offer a 60-day money-back guarantee to reassure you’re choosing it over less expensive preparations.

LeanBean

One of the best appetite suppressant formulas on the market, Leanbean is the next best thermogenic fat burner, although it is specifically for women. It has no harmful ingredients.

  • No harmful ingredients
  • Clinically proven glucomannan
  • Boosts energy and focus
  • Fairly expensive compared to other brands
  • Limited options to choose from

Leanbean may seem “too-good-to-be-true”–a formula enthused by women around the world. Its ingredients promote fat burning and weight loss but focus mainly on appetite suppression. One of its ingredients, glucomannan, is a water-soluble dietary fiber extracted from the roots of konjac, or elephant yam, and this has been clinically proven[2] to suppress your appetite, helping you lose weight. 

Leanbean contains a high, 3-gram dose of glucomannan in each serving, which absorbs liquids in your stomach and makes you feel fuller for longer. In addition, the formula also contains choline, chromium, zinc, vitamins B6 and B12, chloride, green coffee, acai berry, turmeric, Garcinia cambogia, and piperine. All of these ingredients work in sync to promote fat burn, weight loss, a faster metabolism, increased focus, and higher energy.

Instant Knockout

If you’re big into a gym schedule but not seeing the wanted results, Instant Knockout may be the best thermogenic fat burner choice for you! Helps shred unwanted fat while defining your hard-earned muscles.

  • Scientifically formulated
  • High-quality, natural ingredients
  • Vegan-friendly 
  • Not for everyone–targeted primarily on athletes
  • Multiple caffeine-containing ingredients which might cause stimulation issues in some people

Instant Knockout has an amazing fat-burning formula that speeds up your metabolism, helps burn fat and lose weight, suppresses the appetite, and increases energy levels. It was developed specifically for professional mixed martial arts (MMA) fighters but works for everyone, men and women alike. 

The ingredient list includes green tea extract, cayenne pepper seeds, glucomannan, caffeine, vitamins B6 and B12, chromium, zinc, piperine, and green coffee bean. To reap all the benefits, these are spread out in four capsules you take throughout the day. However, be aware of the higher levels of caffeine, which can have adverse effects.  

The form of caffeine used is anhydrous caffeine[3], a highly concentrated form of stimulant which usually is used to boost performance to an extremely intense level. Therefore, people may react differently to it than to natural forms of caffeine, and this can be especially serious if there’s a history of heart conditions, such as arrhythmias. 
Also, since the FDA recommends[4] a maximum daily caffeine intake of 400 mg, taking this fat-burner supplement may make it easy to exceed this limit.

PhenGold

PhenGold

Up to 55% Off When Buying in Bulk

PhenGold is a premium blend of vitamins, minerals, and extracts that are naturally sourced and designed to help you burn fat, lose weight and feel better overall.

  • Clinically proven ingredients
  • Reduces cravings
  • Natural ingredients
  • More expensive than others
  • High caffeine content

The all-natural, multi-action formula of PhenGold makes it very appealing to both men and women looking to shed those unwanted fat deposits. It consists of green tea extract, green coffee extract, L-theanine, L-tyrosine, Rhodiola, cayenne pepper, caffeine, DMAE (Dimethylaminoethanol), and vitamins B3, B6, and B12. 

A great thing about PhenGold is that it’s made in FDA-approved and GMP (Good Manufacturing Practice) certified facilities in the USA, ensuring its safety and trustworthiness. Thousands of satisfied customers have confirmed achieving great results with the PhenGold formula, helping them jumpstart their weight loss journey.

TrimTone

One of the most straightforward of all fat burner supplements, it takes only one pill to achieve results. TrimTone’s natural formula helps speed up metabolism, burn fat, and keep your blood sugar stable in a normal range.

  • Natural ingredients
  • Boost energy and focus
  • Convenient and easy to use (only one pill)
  • Targeted mostly towards women
  • Not suitable for vegans or vegetarians
  • High caffeine content

TrimTone has a 100% natural formula that helps burn fat, curb appetite, boost energy levels and focus, and then it does all that in just one pill. Easy to take before breakfast and fit into your morning routine, TrimTone is targeting busy women who are always on the go and can’t be bothered with setting their alarms to take four pills throughout the day. 

The ingredient list features glucomannan, anhydrous caffeine, green coffee extract, green tea extract, and grains of paradise (a very potent thermogenic herb). The formula might consist of only five ingredients, but together they’re a powerful bunch, helping to heal your body from the inside to burn body fat more efficiently, boost your metabolism, and reduce your appetite. 

Be wary of the caffeine content in this formula, though. Anhydrous caffeine is concentrated caffeine, and it can be dangerous if you’re sensitive to it or have heart conditions.

PrimeShred

One of the most straightforward of all fat burner supplements, it takes only one pill to achieve results. TrimTone’s natural formula helps speed up metabolism, burn fat, and keep your blood sugar stable in a normal range.

  • Vegetarian & vegan friendly
  • Helps maintain muscle mass while burning fat
  • High potency formula in a 3-step approach
  • On the expensive side (although it offers free shipping)
  • Not a lot of information about the company who manufactured the product
  • High caffeine content

PrimeShred is an extremely potent formula consisting of L-Theanine, L-Tyrosine, cayenne pepper, Rhodiola Rosea, green tea extract, green coffee bean extract, anhydrous caffeine, DMAE, Bioperine, and vitamin B complex. 

It’s the best thermogenic fat burner supplement that helps you preserve lean muscle mass while burning excess fat. It also supports your energy, mental clarity, and focus, helping you push through the most challenging parts of your weight-loss diet. 

It does contain a high amount of caffeine, so be careful when taking this weight loss supplement for the first time or if you may have heart issues.

 Okinawa Flat Belly Tonic

Okinawa Flat Belly Tonic is an all-natural, stimulant-free fat burner that helps you lose weight and burn belly fat with only one cup per day.

  • Made in an FDA-approved and GMP facility
  • Ease of use (one cup per day)
  • All-natural Japanese formula
  • Stimulant-free
  • Only available online on their website
  • More expensive, but offers savings when you buy bundles

Okinawa Flat Belly Tonic offers more than just a fat-burning formula: it comes with a 21-day flat belly manual for its 3-week belly fat burning system, including essential dieting tips to help you lose weight the natural and healthy way. It also comes with an amazing digital recipe guide that offers smoothies to suppress the activation of the C-reactive protein (CRP)[5] which has been associated with weight gain and inflammation. 

Additionally, Okinawa Flat Belly Tonic comes with a digital nutrition guide to maintaining a healthy diet, as well as 100 fat-burning recipes that include energy-boosting smoothies. The fat-burning formula consists of piperine, EGCG (Epigallocatechin gallate), Hibiscus sabdariffa, inulin, mulberry, acai berry, Momordica charantia, and Aronia berry. 

In addition to burning fat and boosting your metabolism, these powerful ingredients help strengthen your immune system, increase energy levels, target visceral belly fat, control blood sugar levels, suppress appetite and calorie intake, help maintain cholesterol levels, and reduce the amount of fat absorbed after food consumption.

Potential Side Effects

All-natural fat burner brands claim their products cause no known negative side effects. Still, most of them do contain high doses of caffeine which may cause some side effects in those sensitive to caffeine or who have heart issues with caffeine stimulation. 

Additionally, if the brand you’re using doesn’t contain only natural ingredients, there’s always the risk of having a negative side effect to the synthetic compounds. 

Who Should Stay Away From Thermogenic Fat Burners?

Even with the most natural ingredients, herbs are still considered chemicals and thus can still be dangerous for some groups of people:

  • Pregnant women: the majority of all supplements are considered unsafe or potentially dangerous for pregnant women and/or their babies. It’s always best to stay away from these types of fat-burning supplements when in this blissful state. Taking anything out of the ordinary goes into two people–you and your baby.
  • Breastfeeding women: the same goes for breastfeeding women. There’s always a chance of the baby ingesting herbal ingredients through the breastmilk and potentially having negative side effects.
  • Those on specific medications: if you’re currently on any kind of medication, consult your doctor before taking thermogenic fat-burning pills as there might be some contraindications with the ingredients in your medication. Remember, the ingredients may be the same for all people, but not all people are the same for all the ingredients!

Diet and Exercise

Not even the best, all-natural fat burners can do the work alone. You have to include your diet and exercise in the picture as well. Staying away from processed foods and excess sugars, as well as making sure you’re taking in the right amount of protein, healthy fats, and carbohydrates (carbs) will help you lose fat and preserve muscle the fastest. 

The best type of exercise for you is the one you can stick to, and it’s the one you enjoy doing. If you hate running, there’s no point in making it a part of your daily regimen, as you will most likely feel miserable throughout each second, only aggravating your stress and inflammation. Misery is a recipe for failure; make diet and exercise choices you enjoy for a lifetime commitment.

Thus, choose the activity you enjoy to enhance the fat-burning process and bring more heat to all the areas of the body with which the thermogenic fat-burners work. The stubborn fat won’t go away by itself. It does need a booster! Indeed, you’ll find that all of these good habits strengthen the good achieved with the others. The sum is greater than the addition of the parts!

Thermogenic weight-loss supplements can be a great ally when combined with a high-quality diet and a decent amount of exercise, so using them together makes a powerful combination that will make you lose body fat much faster and help you keep it off in the future.

Final Thought

Weight-loss supplements come in all forms, but those with thermogenic activity help heat up your body from the inside, targeting that stubborn body fat and aiding your weight loss journey. They’re not magic pills and they’re best used with a healthy, nutritious diet and with exercise, promoting a faster metabolism, shrinking those fat cells, increasing energy levels, sharpening your focus, and helping you become more confident in your toned body.

Frequently Asked Questions

What is a thermogenic fat burner?

A thermogenic fat burner is a weight-loss supplement with a specifically-designed formula that heats up the body from the inside, promoting fat-burning and weight loss while curbing your appetite, boosting energy levels, and improving your overall mood.

Are fat burners safe to use?

Anything introduced into the body can do anything to it, but if the formulas are made with completely natural ingredients, they are definitely safer to use than those with synthetic ingredients.

How long does one tub of fat-burning pills last?

This changes from brand to brand, but most have designed their packages to last for about a month. Some come in the form of only one pill, while others recommend taking three or four per day.

How fast can you see results?

This depends on the individual, but most people report noticing results in as little as two weeks after starting the program.

Do you have to diet and exercise?

Yes, fat-burners don’t really work on their own. Their magic lies in enhancing the effects of keeping a healthy diet and exercising, helping you shed body fat and burn calories.

Are natural fat-burners covered by insurance?

Unfortunately, no. Insurance companies typically won’t cover the price of fat-burning pills, which is curious, considering the expense these companies incur treating conditions directly related to obesity and sedentary lifestyles.


+ 6 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Jeukendrup, A.E. and Randell, R. (2011). Fat burners: nutrition supplements that increase fat metabolism. Obesity Reviews, [online] 12(10), pp.841–851. Available at: https://pubmed.ncbi.nlm.nih.gov/21951331/ [Accessed 14 Feb. 2022].
  2. Birketvedt GS;Shimshi M;Erling T;Florholmen J (2012). Experiences with three different fiber supplements in weight reduction. Medical science monitor : international medical journal of experimental and clinical research, [online] 11(1). Available at: https://pubmed.ncbi.nlm.nih.gov/15614200/ [Accessed 14 Feb. 2022].
  3. Trexler, E.T., Smith-Ryan, A.E., Roelofs, E.J., Hirsch, K.R. and Mock, M.G. (2015). Effects of coffee and caffeine anhydrous on strength and sprint performance. European Journal of Sport Science, [online] 16(6), pp.702–710. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803635/ [Accessed 14 Feb. 2022].
  4. Office (2021). Spilling the Beans: How Much Caffeine is Too Much? [online] U.S. Food and Drug Administration. Available at: https://www.fda.gov/consumers/consumer-updates/spilling-beans-how-much-caffeine-too-much [Accessed 14 Feb. 2022].
  5. Nehring, S.M., Goyal, A., Bansal, P. and Patel, B.C. (2021). C Reactive Protein. [online] Nih.gov. Available at: https://www.ncbi.nlm.nih.gov/books/NBK441843/ [Accessed 14 Feb. 2022].
  6. Dulloo, A.G., Duret, C., Rohrer, D., Girardier, L., Mensi, N., Fathi, M., Chantre, P. and Vandermander, J. (1999). Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. The American Journal of Clinical Nutrition, [online] 70(6), pp.1040–1045. Available at: https://academic.oup.com/ajcn/article/70/6/1040/4729179 [Accessed 14 Feb. 2022].

Medically reviewed by:

Karla is a published author, speaker, certified nutritionist, and yoga teacher, and she's passionate when writing about nutrition, health, fitness, and overall wellness topics. Her work has been featured on popular sites like Healthline, Psychology.com, Well and Good, Women's Health, Mindbodygreen, Medium, Yoga Journal, Lifesavvy, and Bodybuilding.com. In addition to writing about these topics, she also teaches yoga classes, offers nutrition coaching, organizes wellness seminars and workshops, creates content for various brands & provides copywriting services to companies.

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