03:18am Saturday 21 October 2017

Certain Obese People are not at High Risk of Heart Disease, Diabetes

The results will be presented Saturday at The Endocrine Society’s 92nd Annual Meeting in San Diego.

“Some obese persons have a normal cardiovascular risk profile, and they have no increased risk for heart and blood vessel disease [because of their weight],” said study co-author André van Beek, MD, PhD, of University Medical Center Groningen, Groningen, the Netherlands. “However, periodic evaluation of their risk profile remains essential.”

The Dutch study found that in a large population of obese individuals, only 6.8 percent were “metabolically healthy,” meaning they had no history of heart disease or stroke, no diabetes or high blood pressure, and no dyslipidemia (irregularities in blood fats, including cholesterol and triglycerides) or any use of cholesterol-lowering medications.

To conduct the research, the authors identified 1,325 obese individuals from 8,356 subjects participating in the Dutch PREVEND (Prevention of Renal and Vascular Endstage Disease) study, who ranged in age from 28 to 75 years. Only 90 obese subjects were metabolically healthy.

Over 7½ years, cardiovascular disease developed in just one of these 90 individuals. This percentage (1.1 percent) was not significantly higher than that in metabolically healthy subjects who were overweight (1.3 percent) or of normal weight (0.6 percent), the researchers reported.

These results indicate that metabolically healthy obese individuals appear to have protection against cardiovascular disease, van Beek said. However, he added, “They are a small subset of the total obese population. And they may still suffer from other obesity-associated diseases like muscle and joint complaints.”

 

 

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Founded in 1916, The Endocrine Society is the world’s oldest, largest, and most active organization devoted to research on hormones and the clinical practice of endocrinology. Today, The Endocrine Society’s membership consists of over 14,000 scientists, physicians, educators, nurses and students in more than 80 countries. Together, these members represent all basic, applied, and clinical interests in endocrinology. The Endocrine Society is based in Chevy Chase, Md. To learn more about the Society, and the field of endocrinology, visit our web site at www.endo-society.org. 

Contacts:
Arlyn G. Riskind      
Director, Media Relations     
Phone: (301) 941-0240      
Email: ariskind@endo-society.org

Aaron Lohr
Manager, Media Relations
Phone: (240) 482-1380
Email: alohr@endo-society.org


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