Intermittent Claudication 2024: Symptoms, Causes & Treatment

Stephanie Nichols

Updated on - Written by
Medically reviewed by Brittany Ferri, Ph.D.

intermittent claudication

Do you experience pain or cramping in your legs during physical activity? If so, you may be suffering from a medical condition known as claudication. Claudication is caused by reduced blood flow to the muscles of the lower extremities due to arterial blockage or narrowing, typically caused by peripheral artery disease (PAD)[1]. While claudication symptoms can vary, pain or cramping in the legs, thighs, calves, or buttocks during physical activity is the most common symptom.

What Are the Symptoms of Claudication?

The symptoms of claudication[2] can vary from person to person, but the most common symptom is pain or cramping in the legs, thighs, calves, or buttocks. This pain usually occurs during physical activity and goes away with rest. Other symptoms may include numbness, tingling, weakness, or a feeling of heaviness in the legs.

The severity of claudication can also vary depending on the extent of arterial blockage or narrowing. In some cases, individuals may only experience mild discomfort, while in others, the pain can be severe enough to limit mobility and quality of life. The symptoms of claudication can worsen over time if left untreated.

It is essential to seek medical attention if you experience any symptoms of claudication, as early diagnosis and treatment can help prevent complications and improve outcomes. Treatment options for claudication may include lifestyle modifications, medication, or in severe cases, surgery or other procedures to improve blood flow to the affected area.

What Is Intermittent Claudication?

intermittent claudication
Woman with lower back and leg pain

Claudication[3] is a medical condition characterized by pain, discomfort, or cramping in the legs during physical activity, such as walking or climbing stairs. It occurs due to a reduction in blood flow to the muscles of the lower extremities, typically as a result of arterial blockage or narrowing. The most common cause of claudication is peripheral artery disease (PAD), which is caused by the buildup of plaque in the arteries supplying blood to the legs.

The severity of claudication can vary from person to person, and the symptoms can range from mild discomfort to severe pain that limits mobility and quality of life. The symptoms of claudication usually occur during physical activity and go away with rest. However, if left untreated, the symptoms can worsen over time, making it challenging to perform even simple activities.

Early diagnosis and treatment are the key to successfully managing intermittent claudication, preventing complications, and improving health outcomes. Treatment options for claudication may include lifestyle modifications, medication, or in severe cases, surgery or other procedures to improve blood flow to the affected area.

What Causes Claudication?

intermittent claudication
Woman with lower body pain

Claudication is caused by a reduced blood flow to the muscles in the lower extremities, usually as a result of arterial blockage or narrowing. The most common cause of claudication is peripheral artery disease (PAD), which occurs when the arteries that supply blood to the legs become narrowed or blocked by a buildup of plaque.

The buildup of plaque, known as atherosclerosis, can occur due to a variety of factors, including smoking, high blood pressure, high cholesterol, diabetes, and a sedentary lifestyle. These factors can damage the inner lining of the arteries, leading to the formation of plaque that can restrict blood flow. Find out about foods that can lower high blood pressure naturally!

Other causes[4] of claudication include blood clots, which can block blood flow to the legs, and vasculitis, which is inflammation of the blood vessels. Rarely, claudication may be caused by a structural abnormality in the blood vessels, such as an aneurysm or a narrowing due to a congenital condition.

Certain factors may increase the risk of developing claudication, including age, smoking, diabetes, high blood pressure, high cholesterol, and a family history of cardiovascular disease. Additionally, individuals who are overweight or obese and those with a sedentary lifestyle may be at increased risk.

What Are the Risk Factors For Claudication?

One of the most significant risk factors for claudication is peripheral artery disease (PAD). PAD is caused by a buildup of plaque in the arteries, which leads to a narrowing or blockage of blood flow. Other risk factors for claudication include age, smoking, high blood pressure, high cholesterol, diabetes, obesity, and a family history of cardiovascular disease.

Age is a significant risk factor for claudication, with the risk increasing as people get older. Smoking is another significant risk factor, as it damages the inner lining of the arteries, making it easier for plaque to form. High blood pressure, high cholesterol, and diabetes are also risk factors, as they can damage the arteries over time and lead to the development of plaque.

Obesity is another risk factor for claudication, as it increases the workload on the heart and blood vessels, making it more difficult for blood to flow through the arteries. Finally, a family history of cardiovascular disease can increase the likelihood of developing claudication, as genetic factors may play a role in the development of the condition.

It is important to manage these risk factors to prevent the development of claudication. This may include lifestyle modifications such as quitting smoking, eating a healthy diet, exercising regularly, and managing any underlying health conditions such as high blood pressure, high cholesterol, or diabetes.

How Do You Diagnose Claudication?

Ankle-Brachial Index (ABI)

This test involves measuring the blood pressure in the arms and ankles to determine if there is a difference in blood pressure that could indicate peripheral artery disease (PAD). A low ABI[5] reading is suggestive of PAD and may indicate a need for further testing or treatment.

Doppler Ultrasound

Doppler Ultrasound[6] uses sound waves to produce images of the blood vessels in the legs and detect any narrowing or blockages. This test is painless and non-invasive, making it a popular option for diagnosing claudication.

Magnetic Resonance Imaging (MRI) or Computed Tomography (CT) Angiography

In some cases, a healthcare professional may also recommend a magnetic resonance imaging (MRI) or computed tomography (CT) angiography[7] to get a more detailed image of the blood vessels and identify any blockages or narrowing.

Ultimately, the diagnostic process for claudication will depend on the individual case and the healthcare professional’s judgment. Early diagnosis and treatment are essential to prevent complications and improve outcomes, so it is important to seek medical attention if you experience any symptoms of claudication.

How Do You Treat Claudication?

Lifestyle Modifications

Lifestyle modifications are often the first line of treatment for claudication. This may include quitting smoking, as smoking damages the blood vessels and increases the risk of developing peripheral artery disease (PAD). Regular exercise[8] can also improve blood flow and reduce symptoms of claudication. Patients may be advised to work with a physical therapist to develop an exercise program that is safe and effective for their individual needs.

Medication

Medication[9] may also be used to treat claudication. Drugs that reduce blood pressure or cholesterol levels, such as beta-blockers or statins, may be prescribed to help manage underlying cardiovascular risk factors that can contribute to the development of claudication. In some cases, antiplatelet drugs or blood thinners may be used to reduce the risk of blood clots that can further restrict blood flow.

Surgery

In severe cases of claudication, surgical or minimally invasive procedures may be necessary to restore blood flow to the affected area. These may include angioplasty, stenting, or bypass surgery, which can help open blocked or narrowed arteries and improve blood flow.

Ultimately, the best course of treatment for claudication will depend on the individual case and the underlying cause of the condition. Early diagnosis and treatment are essential to prevent complications and improve outcomes, so it is important to seek medical attention if you experience any symptoms of claudication.

Exercises For Intermittent Claudication

intermittent claudication
Exercise for intermittent claudication

Exercise[10] is an essential component of the management of intermittent claudication, a condition that causes pain and discomfort in the legs during physical activity due to reduced blood flow to the muscles in the lower extremities. Regular exercise can improve blood flow and reduce the severity of symptoms, allowing individuals with claudication to maintain a higher level of physical activity and improve their overall quality of life.

The recommended exercise program for individuals with claudication usually involves a combination of aerobic exercise and strength training. Aerobic exercise, such as walking, cycling, or swimming, can help improve cardiovascular fitness and increase blood flow to the legs. The goal is to gradually increase the amount and intensity of exercise over time, while monitoring symptoms and adjusting the program as needed. Those that experience pain after exercise will want to check out this CBD cream for pain

Strength training exercises, such as leg presses or calf raises, can help improve muscle strength and endurance, which can reduce the workload on the arteries during physical activity and decrease the severity of symptoms.

In some cases, supervised exercise programs may be recommended, which can help ensure that the exercise program is safe and effective for the individual’s needs. A physical therapist or exercise specialist can work with the individual to develop a personalized exercise program and provide guidance on proper technique and progression.

The Takeaway

In conclusion, claudication is a medical condition that causes pain and discomfort in the legs during physical activity, typically due to reduced blood flow to the muscles of the lower extremities, as a result of arterial blockage or narrowing.

The most common cause of claudication is peripheral artery disease (PAD). The symptoms of claudication can vary, but the most common symptom is pain or cramping in the legs, thighs, calves, or buttocks, which usually occurs during physical activity and goes away with rest. Other symptoms may include numbness, tingling, weakness, or a feeling of heaviness in the legs. It is essential to seek medical attention if you experience any symptoms of claudication, as early diagnosis and treatment can help prevent complications and improve outcomes.

Treatment options for claudication may include lifestyle modifications, medication, or in severe cases, surgery or other procedures to improve blood flow to the affected area. Managing risk factors such as quitting smoking, eating a healthy diet, exercising regularly, and managing underlying health conditions such as high blood pressure, high cholesterol, or diabetes, are important in preventing the development of claudication. Ultimately, early diagnosis and treatment are essential to prevent complications and improve outcomes for individuals with claudication.


+ 10 sources

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  1. Meru, A.V., Shivani Mittra, Thyagarajan, B. and Chugh, A. (2006). Intermittent claudication: An overview. [online] 187(2), pp.221–237. doi:https://doi.org/10.1016/j.atherosclerosis.2005.11.027.
  2. Meru, A.V., Shivani Mittra, Thyagarajan, B. and Chugh, A. (2006). Intermittent claudication: An overview. [online] 187(2), pp.221–237. doi:https://doi.org/10.1016/j.atherosclerosis.2005.11.027.
  3. Meru, A.V., Shivani Mittra, Thyagarajan, B. and Chugh, A. (2006). Intermittent claudication: An overview. [online] 187(2), pp.221–237. doi:https://doi.org/10.1016/j.atherosclerosis.2005.11.027.
  4. P. Abdulhannan, Russell, D.M. and Shervanthi Homer-Vanniasinkam (2012). Peripheral arterial disease: a literature review. [online] 104(1), pp.21–39. doi:https://doi.org/10.1093/bmb/lds027.
  5. Fan, H., Hu, X.-H., Yu, W., Cao, H., Wang, J., Li, J., Liu, B., Yuan, Y. and Zhang, Q. (2013). Low ankle-brachial index and risk of stroke. [online] 229(2), pp.317–323. doi:https://doi.org/10.1016/j.atherosclerosis.2013.05.014.
  6. Creager, M.A. (1997). Clinical Assessment of the Patient with Claudication: The Role of the Vascular Laboratory. doi:https://doi.org/10.1177/1358863×9700200312.
  7. LWW. (2023). Dynamic Effects on the Lumbar Spinal Canal: Axially Loaded… : Spine. [online] Available at: https://journals.lww.com/spinejournal/Abstract/1997/12150/Dynamic_Effects_on_the_Lumbar_Spinal_Canal_.21.aspx.
  8. Watson, L., Ellis, B.E. and Leng, G. (2008). Exercise for intermittent claudication. [online] doi:https://doi.org/10.1002/14651858.cd000990.pub2.
  9. Hiatt, W.R. (2001). Medical Treatment of Peripheral Arterial Disease and Claudication. [online] 344(21), pp.1608–1621. doi:https://doi.org/10.1056/nejm200105243442108.
  10. Watson, L., Ellis, B.E. and Leng, G. (2008). Exercise for intermittent claudication. [online] doi:https://doi.org/10.1002/14651858.cd000990.pub2.
Stephanie Nichols

Medically reviewed by:

Brittany Ferri

Dr. Stephanie Nichols is a licensed Naturopathic Doctor in Arizona. She’s passionate about helping women resolve their anxiety, depression, and chronic stress through restoring balance to their hormones, and digestive functioning. She also approaches autoimmune conditions from a whole-person standpoint and uncovers the deeper issues through advanced laboratory testing. Dr. Stephanie assesses her patients from a Naturopathic as well as a Traditional Chinese Medicine viewpoint. Her treatment plans are unique in that they are completely customized to suit each patient on a mental, emotional, and physical level. Dr. Stephanie earned her bachelor’s degree in Nutrition and Food Sciences, with honors, from the University of Alberta. After recognizing the ability of food choices to impact several chronic diseases, she then pursued her Doctorate in Naturopathic Medicine from the Southwest College of Naturopathic Medicine, graduating with honors.She is a consultant and nutraceutical formulator for a number of companies as well as a freelance medical blog writer.

Medically reviewed by:

Brittany Ferri

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