University of Adelaide researchers have developed a world-first optical sensor that can detect vitamin B12 in diluted human blood – a first step towards a low-cost, portable, broadscale vitamin B12 deficiency test. Vitamin B12 deficiency is associated with an increased risk of dementia and Alzheimer's disease.
When people are deprived of food, a number of biological mechanisms are set in motion to adapt the body’s metabolism to the conditions of scarcity. One of these processes has been revealed by a team of Belgian researchers, led by professor Karolien De Bosscher (VIB-Ghent University). The scientists discovered how three important proteins collaborate on a genetic level to provide a response to long-term fasting. The insights are published in the leading scientific journal Nucleic Acids Research, and could ultimately be put to use in clinical environments to treat metabolic diseases more efficiently.
Scientists at the German Cancer Research Center (DKFZ) have shown in mice that a low-protein diet increases fat and carbohydrate burning, thus raising energy expenditure. Changing the animals' diet to low-protein intake even led to the regression of insulin resistance – independent of their body weight and total energy intake. A temporary low-protein diet also lowered insulin and glucose levels in young human volunteers. This effect is regulated by a central stress response by liver cells.
BOSTON — Eating less may help us lead longer, healthier lives, according to the new results from a large, multicenter study, led by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University. The paper, published in Aging, reveals that restricting calories by 25 percent in healthy non-obese individuals over two years, while maintaining adequate protein, vitamin, and mineral intake, can significantly lower markers of chronic inflammation without negatively affecting other parts of the immune system.
BOSTON—Butter consumption was only weakly associated with total mortality, not associated with cardiovascular disease, and slightly inversely associated (protective) with diabetes, according to a new epidemiological study which analyzed the association of butter consumption with chronic disease and all-cause mortality. This systematic review and meta-analysis, published in PLOS ONE, was led by Tufts scientists including Laura Pimpin, Ph.D., former postdoctoral fellow at the Friedman School of Nutrition Science and Policy at Tufts in Boston, and senior author Dariush Mozaffarian, M.D., Dr.P.H., dean of the School.
A Mediterranean diet which is rich in vegetal fats (extra virgin olive oils, dried fruit and nuts, etc.) does not mean it comes with weight gain if compared to a low-fat diet, according to a study published in the medical journal The Lancet Diabetes & Endocrinology. This work suggests that lots of current guidelines on health giving advice on reducing fat and calories give a wrong idea of the effects of consuming Mediterranean diet fats, a diet with well known health benefits.