Best Vitamins For Acne Of 2023: Top 5 Choices For Clear Skin

Lindsey Desoto

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

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Skinny Fit Daily Grow

SkinnyFit Daily Glow

  • 90-day money-back guarantee
  • Formulated with clinically studied ingredients
  • May support a healthy complexion

HUM Glow Sweet Glow

HUM Glow Sweet Glow

  • Convenient, gummy form
  • Free of artificial colors, sweeteners, flavors & preservatives 
  • Third-party tested

MegaFood Skin, Nails & Hair 2

MegaFood Skin, Nails & Hair 2

  • Includes real food ingredients
  • Vegan-friendly
  • Made with clinically studied ingredients

Acne is the most common skin condition in the United States, affecting as many as 50 million[1] Americans yearly.

Scientists are still trying to figure out why some people are more prone to acne, but it is believed that hormones play a role.[2] When certain hormones cause sebaceous glands to produce more oil than normal, skin pores can get clogged, allowing pimples and bacteria to grow.

Acne treatment[3] generally consists of a well-balanced diet, topical medications like benzoyl peroxide and salicylic acid, antibiotics, oral medications containing vitamin A, corticosteroids, and hormone therapy to balance hormones.

More recently, people have started looking into more natural acne treatments, such as minerals and vitamins. But do they actually work? And if so, which ones are the most beneficial?

This article discusses the best vitamins for acne and acne scars, including potential benefits and drawbacks.

5 Best Vitamins For Acne On The Market In (May. 2023)

Can Vitamins Help With Acne?

The mechanism behind the benefits of specific vitamins and minerals for acne remains unclear, and additional research is needed before any supplement can be routinely recommended for treating acne.

However, it is believed that specific vitamins may help hormonal acne by targeting various aspects of acne development.

One study[4] found that individuals with acne were more likely to have significantly lower blood levels of zinc, vitamin A, and vitamin E than those without acne. 

Researchers concluded that a diet rich in these nutrients might help prevent and treat acne.

Which Vitamins Help You Clear Acne?

The following nutrients have the most scientific evidence to support their effectiveness in improving skin health.

Vitamin A

Vitamin A is an antioxidant that may help support healthy skin by fighting off free radicals. It may also reduce inflammation,[5] an underlying hormonal acne factor.

Topical vitamin A is the most promising form[6] of vitamin A for treating acne and acne scars. 

Some studies[7] suggest that high doses of vitamin A well beyond the current Recommended Daily Allowance may produce results similar to isotretinoin (Accutane), which is used to treat moderate to severe acne. 

However, the use of high-dose vitamin A should be only consumed under the close supervision of a healthcare professional due to its potential for toxicity. 

Excess in vitamin A consumption can lead to hypervitaminosis A,[8] which can cause symptoms like muscle soreness, headaches, dry skin, nausea, fatigue, hair loss, and liver damage. It can also cause severe damage to a developing baby when levels are high during pregnancy. 


Zinc is an essential mineral that helps your metabolism and immune system function. Studies[9] suggest that topical and oral supplements containing zinc can help reduce acne. This is because it possesses antibacterial and anti-inflammatory properties. Zinc may also help reduce excess oil production in the skin.

Vitamin E

Vitamin E is an antioxidant known for fighting inflammation and aiding skin cell regeneration.

One study[10] found that, when combined with lactoferrin (a protein found in human milk) and zinc, vitamin E significantly reduced acne lesions in acne sufferers with mild to moderate acne.

That said, research on the effectiveness of vitamin E for treating acne scars and acne is still being determined,[11] and further research is needed.

5 Best Vitamins For Acne To Have Glowing Skin In 2023

SkinnyFit Daily Glow

SkinnyFit Daily Glow comes with a generous money-back guarantee and contains clinically studied ingredients that may support a healthy complexion.

  • May support a healthy complexion
  • Formulated with clinically studied ingredients
  • 90-day money-back guarantee
  • Lacks third-party testing
  • Contains 1,923% of the DV for vitamin B6, which may worsen acne
  • Has 333% of the DV for vitamin E, which is excessive for a fat-soluble vitamin

SkinnyFit’s Daily Glow is an all-natural hair, skin, and nail supplement designed to support healthy nails, a youthful complexion, and a brighter complexion.

Daily glow contains biotin, kelp powder, and vitamins C and E. It also contains B vitamins like B3, B5, and B6. 

Studies suggest that vitamin B3,[12] called niacin, and vitamin C[13] are potential treatment options for acne-prone skin thanks to their potent anti-inflammatory effects. However, research is limited, and further studies are needed to determine its effectiveness in treating acne.

Another 12-week study[14] in adults with mild to moderate acne found that acne sufferers who used topical treatments and an oral supplement containing biotin, vitamin E, zinc, vitamin B3, and other vitamins experienced significant improvements.

Studies[15] also suggest that vitamin B5, also known as pantothenic acid, may help reduce blemishes and the number of inflamed lesions in individuals with mild to moderate acne.

The Daily Value, also known as DV, for most of the nutrients in one two-capsule serving far exceeds what is currently recommended based on a 2,000-calorie diet. Getting too much of certain nutrients[16] may be harmful to your health.

All products sold by SkinnyFit come with a 90-day money-back guarantee. However, there is no proof that their products are third-party tested. One 30-serving bottle costs $52.95.

HUM Glow Sweet Glow

HUM Glow Sweet Glow is formulated by dietitians, comes in a tasty vegan gummy form, and contains 100% of the DV for vitamins C and E, which may boost your skin’s appearance.

  • Formulated by dietitians
  • Third-party tested
  • Vegan gummy form
  • Contains clinically studied ingredients
  • Third-party testing results are not available online

HUM Nutrition is a subscription-based vitamin service that offers customized recommendations based on your unique nutritional needs.

HUM Glow Sweet Glow is formulated by registered dietitian nutritionists and contains 100% of the recommended daily intake for vitamins C and E. It also has 120 milligrams of hyaluronic acid,[17] which may help control sebum production and moisturize skin.

One study[18] found that 84% of people who took 120 milligrams of oral hyaluronic acid daily for six weeks experienced increased skin hydration.

Glow Sweet Glow comes in a tangerine-flavored vegan gummy form and is free of artificial additives, colorings, and excess added sugar. Each two-gummy serving contains two grams of added sugar and is sweetened using evaporated cane juice and tapioca syrup.

All products sold by HUM Nutrition are Clean Label Project Certified and triple-tested and third-party tested for quality, purity, and potency. 

Clean Label Project independently tests for hundreds of harmful chemicals and environmental contaminants like pesticide residues, plasticizers, and heavy metals. Results of third-party testing are not publicly available at this time.

One 30-serving bottle costs $26.

MegaFood Skin, Nails & Hair 2

MegaFood Skin, Nails & Hair 2 contains vitamins, minerals, and real food ingredients designed to support skin health.

  • Includes real food ingredients
  • Vegan-friendly
  • Made with clinically studied ingredients
  • Contains 133% of the DV for vitamin E
  • Lacks third-party testing
  • Contains a proprietary blend

MegaFood Skin, Nails & Hair 2 contains vitamins A, C, E, and B6, pantothenic acid, biotin, zinc, and selenium. It also includes a real food blend composed of organic nettle leaf, organic orange, organic brown rice, and carrot. Many of the nutrients in this oral vitamin are present in daily values that far exceed 100%.

Studies[19] show that zinc and selenium are two of the most important minerals that facilitate the treatment of acne. Selenium regulates sebum production and may help reduce skin inflammation. It is traditionally used in combination with vitamin E and zinc.

The real food blend is a proprietary blend, making it difficult to know how much of each ingredient is present in the product. 

MegaFood Skin, Nails & Hair 2 is suitable for vegan diets and is free of genetically modified organisms, or GMOs. It does not appear to be third-party tested, however. The recommended daily dosage is two tablets daily, with or without food.

A 30-serving container costs $25.99.

Vital Proteins Radiance Boost

Vital Proteins Radiance Boost is a plant-based vitamin supplement with ingredients that may help support skin health.

  • Contains 100% DV for Vitamins A, E, and zinc
  • Includes clinically-studied ingredients
  • Vegan
  • Lacks third-party testing

Vital Proteins Radiance Boost contains various vitamins, including vitamins A, C, and E, and pantothenic acid, which may support healthier, clearer skin. It has other ingredients, such as hyaluronic acid, Verbascoside Verbasnol™, Ceramide-PCD®, and zinc.

Verbascoside Verbasnol™ is made of Rehmannia glutinosa extract, which is known for its anti-inflammatory properties. There are ongoing studies[20] to determine the effectiveness and tolerability of Rehmannia glutinosa extract in treating acne.

Studies also show that ceramide supplements may help increase the skin’s moisture content.[21]

Vital Proteins Radiance Boost is gluten and dairy-free, plant-based, and Whole30-approved. It does not appear that a third party has tested this product. The recommended dose is two capsules per day. A 30-serving bottle costs $30.00. 

Olly’s Flawless Complexion

OLLY Flawless Complexion is a good quality, affordable skin supplement with ingredients that may help improve your skin’s appearance.

  • Very affordable
  • Certified by the National Sanitation Foundation
  • Contains clinically-studied ingredients
  • Not vegan-friendly
  • Contains glucose syrup

OLLY is a supplement company known for its affordable supplements that are loved and appreciated by customers of all ages.

OLLY Flawless Complexion is a berry-flavored gummy made with a blend of antioxidants, minerals, and botanicals to support a clear complexion from the inside out.

It contains vitamins A, D, E, and B6 and other skin-supporting nutrients like zinc and selenium.

Vitamin D plays an essential role in immune health. Vitamin D also has antimicrobial[22] and anti-inflammatory[23] properties, which may benefit acne. Studies[22] suggest that vitamin D deficiency occurs more frequently in individuals with acne, and having adequate vitamin D may help with the inflammatory symptoms of acne.

The gummies have 3 grams of added sugar per two-gummy serving, which is slightly more than HUM Glow Sweet Glow. This added sugar can create plaque on the teeth, presenting a problem for dental caries, so brushing adequately after eating gummies is advisable.

OLLY Flawless Complexion is certified by the National Sanitation Foundation, which tests for harmful levels of contaminants and ensures that supplements contain the ingredients listed on the label.

The recommended dose is two gummies daily, with or without food. It is affordably priced, with a 24-serving container costing just $13.99.

Benefits Of Vitamins For Acne Skin

Currently, there is no solid scientific evidence to recommend using an over-the-counter vitamin supplement instead of traditional acne treatment.

However, studies[19] have confirmed that proper nutrition and a well-balanced diet may help prevent or alleviate symptoms of acne. In particular, vitamins A, C, D, E, and B, zinc, and selenium are critical for supporting traditional acne therapy.

If you have difficulty meeting the recommended amounts of these nutrients through diet alone, you may benefit from taking a high-quality vitamin to complement your ongoing acne therapy. 

What To Look For When Choosing Vitamins For Acne

Here are some things to consider as you source the best vitamins to address your skin concerns.


While a wide range of nutrients plays a role in skin health, individuals with acne are more likely to be deficient in vitamins A, E, and zinc. As such, you may want to consider a supplement that includes these nutrients.

You may also want to avoid supplements containing megadoses of vitamins B6 and B12, which may cause acne or worsen an existing condition.

Lastly, if you have any allergies, always carefully read the ingredient list to ensure it doesn’t contain an ingredient you are allergic to.

Third-Party Testing

The Food and Drug Administration does not regulate dietary supplements for safety and effectiveness. This makes third-party testing vital to verify a supplement’s purity and that its ingredients match the label.

It’s best to purchase supplements from a transparent brand that publishes all third-party testing results online. However, keep in mind that third-party testers do not always test for all contaminants, so it is always a good idea to read the lab report to see what was actually tested for.

Daily Value

When looking at the supplement label, try to choose a supplement that contains as close to 100% of the DV of the ingredients inside. Generally, it’s best to avoid megadoses of nutrients well over the recommended DV. This is especially true for fat-soluble vitamins, such as A, D, E, and K, which can be toxic in large doses and cause health problems.


Currently, there are no official recommendations on the dosage of specific vitamins and minerals to help fight acne, so it’s best to consult a healthcare provider or board-certified dermatologist to establish a safe approach.

However, if you decide to take a vitamin supplement for acne, always follow the manufacturer’s recommendations when consuming dietary supplements, and only take what is recommended.

Final Thought

The nutrients you consume can determine the condition of your skin. A well-balanced, nutrient-rich diet is important to aid in treating and preventing acne. Supplementing your diet with vitamins and minerals can help boost your intake, which may help promote clear skin.

However, vitamin and mineral supplementation may do more harm than good in some cases. As such, it is essential to seek advice from your healthcare provider before taking any supplements to treat acne.

Frequently Asked Questions

How often should you take vitamins for clear skin?

Unless otherwise recommended by your healthcare provider or the product manufacturer, you should be consistent and take your supplement daily for the best results.

How do vitamins for clear skin work?

Certain vitamins and minerals may help clear skin and acne scarring by decreasing inflammation, decreasing sebum production, and promoting the regeneration of healthy skin cells.

Can vitamins for hormonal acne help?

Studies[19] suggest that appropriate dietary intake and supplementation of vitamins A, C, D, E, and B vitamins, as well as zinc and selenium, is vital for maximizing the effectiveness of traditional acne therapy, including treatment for hormonal acne.

Should I take vitamins if I have acne?

Everyone’s skin is different. Vitamins and minerals that work to improve the appearance of one person’s skin may not affect another’s. However, if you fall short in meeting your daily nutrient requirements, you may benefit from a vitamin supplement to lessen inflammation and complement your ongoing acne therapy.

Which vitamins cause acne?

According to one recent 2020 study,[24] some dietary supplements, including iodine, vitamin B6, vitamin B12, whey, and anabolic-androgenic steroids, may cause breakouts.

+ 24 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

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Lindsey Desoto

Medically reviewed by:

Kathy Shattler

Lindsey DeSoto is a Registered Dietitian Nutritionist based out of Coastal Mississippi. She earned her BSc in Nutrition Sciences from the University of Alabama. Lindsey has a passion for helping others live their healthiest life by translating the latest evidence-based research into easy-to-digest, approachable content.

Medically reviewed by:

Kathy Shattler

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