04:20pm Monday 22 October 2018

Depression during pregnancy rises in a generation

Anxiety and depressive symptoms during pregnancy have risen by 51 per cent within a generation according to findings from a major study by the University of Bristol published last week [Friday 13 July].

Using unique data from two generations who took part in Bristol’s Children of the 90s longitudinal study, researchers examined responses to questions completed by the women during pregnancy to compare levels of depressive symptoms more than 20 years apart.

Looking at the responses of 2,390 of the original women who were recruited to the study in the early 1990s and then 180 of their daughter’s generation who became pregnant by the age of 24, researchers found that having high depressive symptoms was 51 per cent more common in the current generation.  Today 25 per cent of young mums have high depressive symptoms compared to 17 per cent in the 1990s according to the research published by JAMA Network Open.

If their mother was depressed in pregnancy, daughters were also more than three times as likely to be depressed in their pregnancy.

It is the first time that scientists have been able to compare mental health symptoms in pregnancy across generations and marks the beginnings of a new wave of health and social policy research that is planned using data from three generations.

This has been made possible by the unique data available in the Children of the 90s study and funding from the Medical Research CouncilWellcome TrustNational Institute for Health ResearchEuropean Research Council and US National Institutes of Health.

Dr Rebecca Pearson, Lecturer in Psychiatric Epidemiology in the Bristol Medical School [PHS], commented: “Thanks to the Children of the 90s data we can now make valuable comparisons between generations on the experienced levels of depression.  While there is a perception that mental health is rising, this may be due to greater awareness and less stigma. These new data give a more accurate picture of what our current population of young pregnant women are facing.

“Interestingly, however, the research shows that depression in today’s young women may be driven by rises in feeling overwhelmed and stress rather than feelings of being down and flat.

“Given that depression in pregnancy has substantial impact to both mother and child this is of key importance for health services. Our next steps will use this resource to look at the consequences of maternal depression on the 2nd generation from the Children of the 90s once they are born. Currently we have parents and their babies set up with head camera technology at home to more closely and realistically examine interactions between parents and babies and how these are influenced by mental health.”

Professor Deborah Lawlor, Principal Investigator for the Children of the Children of the 90s study, added: “We are so thankful to the families that have contributed to this unique study for nearly 30 years. This is a truly unique resource, which places Bristol firmly on the worldwide map as leaders of this kind of population health science research. As we continue to recruit more participants into the study we will be able to better understand how health and wellbeing are passed on down the generations and how to improve the health of future generations.”

Clare Dolman, Vice Chair of the Maternal Mental Health Alliance, said: “This is an important piece of research from the University of Bristol on depression in pregnancy showing that rates of depression have risen within a generation. It is vital now to go further and look at the possible causes of this increase to help devise interventions to break the intergenerational cycle.”

Paper:

‘Prevalence of Antenatal Depression Symptoms Among Two Generations of Pregnant Mothers: The Avon Longitudinal Study of Parents and Children’ by Rebecca M Pearson, Rebecca E Carnegie, Callum Cree, Claire Rollings, Louise Rena-Jones, Jonathan Evans, Alan Stein, Kate Tilling, Melanie Lewcock and Debbie Lawlor in JAMA Network Open

 

The University of Bristol 

 


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