09:59pm Tuesday 12 December 2017

BJOG release: Are my twins identical?

Determining if same-sex twins are identical or non-identical  (from one egg or two; monozygotic or dizygotic) is not always straight forward, say the researchers. They looked at data from the Gemini study, a birth cohort of 2402 families with twins born in England and Wales in 2007.

Parents of same sex twins (1586) were asked if they knew whether their twins were identical or not and how they discovered that information.

The majority of parents (1302/82%) reported that they had been given the information by health professionals based on the formation of the placenta as seen on the prenatal scan. Of this group, as part of the Gemini data collection, all parents completed a validated zygosity questionnaire[i] when their twins were on average 8.2 months old. This questionnaire asks about the children’s height, eye colour, hair colour and overall confusability and has been found in a previous study to correctly assign zygosity in 95% of cases.

The researchers found that out of the 1302 parents, 191 (14.7%) were misinformed about their same sex twins’ zygosity (identical or non-identical).

In addition, 38% of parents said they were told after an antenatal scan that their twins shared a placenta and were therefore identical while 62% of parents were told their twins were non identical as they had two placentas.

However 25-30% of identical twins can have two placentas say the researchers. If the zygote splits within two days of fertilisation, separate placentas develop.

Jane Wardle, Health Behaviour Research Centre, Department of Epidemiology and Public Health, University College London and co-author of the commentary paper said:

“Finding out if your twins are identical or not is important to parents. However our data suggests that there may be a lack of knowledge among some health professionals about both identical and non identical twins having two placentas.

“Parents have the right to the relevant information if it is available. However most parents will understand that it is not always possible to give a specific answer.”

John Thorp, BJOG Deputy-Editor-in-Chief added:

“This paper highlights the uncertainty that can exist in finding out whether same sex twins are identical or not. Additional training may be required for health professionals to avoid giving out the wrong information to parents.”

[1] Price TS, Freeman B, Craig I, Petrill SA, Ebersole L, Plomin R. Infant zygosity can be assigned by parental report questionnaire data. Twin Res 2000;3:129-133.

Ends

For more information please contact Naomi Weston, PR Officer, Royal College of Obstetricians and Gynaecologists:  nweston@rcog.org.uk 020 7772 6357

Notes

BJOG: An International Journal of Obstetrics and Gynaecology is owned by the Royal College of Obstetricians and Gynaecologists (RCOG) but is editorially independent and published monthly by Wiley-Blackwell. The journal features original, peer-reviewed, high-quality medical research in all areas of obstetrics and gynaecology worldwide. Please quote ‘BJOG‘ or ‘BJOG: An International Journal of Obstetrics and Gynaecology’ when referring to the journal and include the website: www.bjog.org as a hidden link online.

Please include a link to the paper in online coverage: http://dx.doi.org/10.1111/j.1471-0528.2012.03281.x

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Reference

van Jaarsveld C, Llewellyn C, Fildes A, Fisher A, Wardle J. Are my twins identical: parents may be misinformed by prenatal scan observations. BJOG 2012; DOI: 10.1111/j.1471-0528.2012.03281.x.


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