HOUSTON – Regardless of an individual’s dietary and lifestyle risk factors, living in a poorer or more socioeconomically deprived neighborhood may increase a person’s risk for death, according to data presented at the American Association for Cancer Research Conference on Frontiers in Cancer Prevention Research, held Dec. 6-9, 2009.
Researchers conducted the NIH-AARP Diet and Health Study and found that people living in poorer neighborhoods, as determined by U.S. Census data, reported higher health risks, including heart disease and cancer, and were more likely to die sooner regardless of lifestyle and other risk factors.
“We were expecting that once we controlled for these lifestyle and medical risk factors, the differences would go away,” said Chyke Doubeni, M.D., M.P.H., assistant professor of family medicine and community health and assistant vice provost for diversity at the University of Massachusetts Medical School. “We weren’t surprised by the unadjusted differences, but we were surprised that the differences persisted after controlling for lifestyle factors such as smoking, diet, exercise and medical risks.”
Previous data have demonstrated that people from lower socioeconomic groups have poorer health outcomes. Doubeni and colleagues prospectively evaluated whether people living in more deprived neighborhoods have a higher mortality risk.
Through the NIH-AARP study, they collected diet, lifestyle and medical history data from a prospective cohort of 565,697 participants, aged 50 to 71, from six U.S. states and two metropolitan areas during 1995 to 1996. Participants’ mean age was 62 years, and the cohort consisted of 60 percent men, 91 percent non-Hispanic whites, 4 percent non-Hispanic blacks and 9 percent had a history of cancer.
Results revealed that a larger percentage of participants living in the most deprived neighborhoods reported poorer general health, higher average body mass index and lower Mediterranean diet scores, meaning that their diets were unhealthy. After Doubeni and colleagues controlled for dietary and lifestyle factors, the risk for death increased as the levels of deprivation in the neighborhood increased.
“We, as practitioners, either in the health care systems or clinics, should be alert to the needs of people from these backgrounds,” Doubeni said. “We need to target public health interventions to these neighborhoods that are deprived by improving health resources and the physical environments in those areas.”
Doubeni and colleagues are currently evaluating how living in a socioeconomically deprived neighborhood may influence overall cancer incidence and mortality, specifically focusing on colorectal cancer.
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The mission of the American Association for Cancer Research is to prevent and cure cancer. Founded in 1907, the AACR is the world’s oldest and largest professional organization dedicated to advancing cancer research. The membership includes 30,000 basic, translational and clinical researchers; health care professionals; and cancer survivors and advocates in the United States and nearly 90 other countries. The AACR marshals the full spectrum of expertise from the cancer community to accelerate progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. It funds innovative, meritorious research grants, research fellowship and career development awards. The AACR Annual Meeting attracts more than 16,000 participants who share the latest discoveries and developments in the field. Special conferences throughout the year present novel data across a wide variety of topics in cancer research, treatment and patient care. The AACR publishes six major peer-reviewed journals: Cancer Research; Clinical Cancer Research; Molecular Cancer Therapeutics; Molecular Cancer Research; Cancer Epidemiology, Biomarkers & Prevention; and Cancer Prevention Research. The AACR also publishes CR, a magazine for cancer survivors and their families, patient advocates, physicians and scientists. CR provides a forum for sharing essential, evidence-based information and perspectives on progress in cancer research, survivorship and advocacy.
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