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Depression

Higher doses of antidepressants are associated with better treatment response

In contrast to what has previously been claimed, low doses of antidepressants are clearly less effective than higher ones. This is the ...

Postpartum Depression Least Severe Form of Depression in Mothers

Time when pregnant woman first develops depression determines severity, treatment of it ...

New Teen Study for Non-Drug Alternative to Treatment-Resistant Depression

A trial at the University of Cincinnati (UC) is looking at how to treat depression for adolescents age 12 to 21 who have not responded to traditional antidepressant treatment. ... Full story

Most antidepressant drugs ineffective for children and teens, study finds

But researchers warn that lack of available data from published and unpublished trials leads to great uncertainty around true effects ... Full story

Blood test to personalise depression treatment for the first time

Scientists at King’s College London have developed a blood test that accurately and reliably predicts whether depressed patients will respond to common antidepressants, which could herald a new era of personalised treatment for people with depression. ... Full story

Brain structure that tracks negative events backfires in depression

A region of the brain that responds to bad experiences has the opposite reaction to expectations of aversive events in people with depression compared to healthy adults, finds a new UCL study funded by the Medical Research Council. ... Full story

Antidepressants: rise in off-label prescriptions

Antidepressant use in North America has increased over the last 2 decades. A suspected reason for this trend is that primary care physicians are increasingly prescribing antidepressants for nondepressive indications, including unapproved (off-label) indications that have not been evaluated by regulatory agencies. ... Full story

Altered purine metabolism linked to depression

People suffering from major depressive disorder may have altered purine metabolism, according to a new study from the University of Eastern Finland and Kuopio University Hospital. Purines are nitrogenous compounds that serve as building blocks for DNA and they also play a role in cellular signalling, among other things. ... Full story

Raising Body Temperature Relieves Depression Symptoms, Small Study Finds

Madison, Wisconsin — Raising the body temperature of depressed volunteers to the equivalent of a mild fever improved their symptoms of major depression for as long as six weeks after a single treatment, results from a new study show. ... Full story

Can a smartphone application help treat anxiety and depression?

In a joint project between the Universities of Liverpool and Manchester, researchers have examined the initial trial of a smartphone application designed to help people manage their problems. ... Full story

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