Resistance to antidepressants linked to metabolism

Often, clinical depression has company; it shows up in the brain alongside metabolic abnormalities, such as elevated blood sugar, in the body. ...

Positive activity’ as effective as ‘positive thinking’ in treating depression

A simple and inexpensive therapy is equally as effective at treating depression as the ‘gold standard’ of Cognitive Behavioural Therapy (CBT), scientists ...

Depression’s stigma can be a barrier to African-Americans seeking treatment, study finds

Athens, Ga. - The stigma attached to mental illness creates a barrier for many seeking treatment, but it has a particularly negative impact on the help-seeking behaviors of black Americans, a small in-depth qualitative study by researchers at the University of Georgia suggests. ... Full story

Half of patients with depression are inadequately treated

New UBC research shows that about 50 per cent of British Columbians with depression are not receiving even the most basic level of care. Authors say the findings highlight the challenges of accessing mental health services across Canada. ... Full story

Depression, adverse childhood events and sleep disturbances linked to changes in the immune system

Adverse childhood experiences and sleep disturbances interfere with immune system regulation, shows research from the University of Eastern Finland. These changes were observed in a population that already carried a significant burden of psychological symptoms such as depression. ... Full story

Higher doses of antidepressants are associated with better treatment response

In contrast to what has previously been claimed, low doses of antidepressants are clearly less effective than higher ones. This is the principal finding of a new study from the Sahlgrenska Academy at the University of Gothenburg in Sweden. The authors also suggest that antidepressants, when used at an optimal dose, are considerably more effective than usually assumed. ... Full story

Postpartum Depression Least Severe Form of Depression in Mothers

Time when pregnant woman first develops depression determines severity, treatment of it ... Full story

New Teen Study for Non-Drug Alternative to Treatment-Resistant Depression

A trial at the University of Cincinnati (UC) is looking at how to treat depression for adolescents age 12 to 21 who have not responded to traditional antidepressant treatment. ... Full story

Most antidepressant drugs ineffective for children and teens, study finds

But researchers warn that lack of available data from published and unpublished trials leads to great uncertainty around true effects ... Full story

Blood test to personalise depression treatment for the first time

Scientists at King’s College London have developed a blood test that accurately and reliably predicts whether depressed patients will respond to common antidepressants, which could herald a new era of personalised treatment for people with depression. ... Full story

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